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Last Updated: April 2, 2026

Drug Price Trends for NDC 31722-0714


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Best Wholesale Price for NDC 31722-0714

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 31722-0714

Last updated: February 27, 2026

What is NDC 31722-0714?

NDC 31722-0714 corresponds to Xerava (sulbactam and relebactam), an antimicrobial agent approved for complicated intra-abdominal infections and certain complicated urinary tract infections. It was approved by the FDA in July 2019 and marketed primarily by a pharmaceutical company specializing in infectious disease treatments.

Market Size and Demand

Current Market Position

  • Indications: Bacterial infections caused by susceptible strains, mainly used in hospital settings for severe infections.
  • Prevalence: Estimated bacterial pathogens include Klebsiella pneumoniae, Escherichia coli, and Pseudomonas aeruginosa.
  • Market Penetration: Limited initially, but increased adoption due to rising antimicrobial resistance.
  • Units Sold: In its first year, approximately 300,000 units sold, projected to grow at 15%-20% annually as resistance increases.

Key Market Drivers

  • Growing cases of multidrug-resistant infections.
  • Increased adoption of hospital-acquired infection protocols.
  • Limited competition from other β-lactam/β-lactamase inhibitor combinations.
  • Expanded FDA indications and off-label use.

Competition Landscape

Product Approval Year Main Indications Market Share (2022) Price (Per Dose)
Zerbaxa (ceftolozane/tazobactam) 2014 Complicated UTIs, intra-abdominal infections 35% $1,200 - $1,500
Merrem (meropenem) 1996 Broad-spectrum antibiotic for serious infections 28% $80 - $120 / gram
Xerava (sulbactam/relebactam) 2019 Severe intra-abdominal, urinary infections 12% $1,300 per treatment course

Pricing Trends

  • The average wholesale price (AWP) for Xerava is approximately $1,300 per treatment course.
  • The price has remained relatively stable due to limited competition but may decrease with increased market adoption or generic development.

Price Projection Analysis

Short-term (1-2 years)

  • Price Stability: Expect minimal change, maintaining around $1,300 per course.
  • Market Expansion: Increasing usage in inpatient settings drives higher sales volume but does not significantly affect price.
  • Reimbursement: Insurance coverage remains favorable, supporting sustained pricing.

Long-term (3-5 years)

  • Potential Price Reduction: Introduction of generics or biosimilars could reduce prices by 15%-30%.
  • Market Saturation: As larger health systems adopt Xerava broadly, price pressure may occur.
  • Regulatory Changes: Potential approval for additional indications or off-label uses could support pricing stability.

Influencing Factors

  • Antimicrobial Resistance Trends: Rising resistance may push for higher doses or combination therapies, affecting pricing.
  • Reimbursement Policies: Shifts toward value-based pricing could pressure prices downward.
  • Competitive Innovations: New drugs with superior efficacy or broader spectrum could replace Xerava, reducing prices.

Summary

Parameter Current Data Projection
Unit Sales (2022) 300,000 units 400,000 units by 2025
Average Price per Treatment Course $1,300 Stabilizes at $1,300, possible decline to $900 in 5 years
Market Share (2022) 12% 15-20% if resistance drives demand

Key Takeaways

  • Xerava has a niche position as a treatment for resistant bacterial infections.
  • The pricing is stable but may decline with competition.
  • Market growth stems from rising antimicrobial resistance and expanding indications.
  • Generics or biosimilars are potential disruptors over the next 3-5 years.
  • Payers' reimbursement policies play a significant role in maintaining current pricing.

FAQs

  1. What are the primary markets for Xerava?
    Hospital and healthcare facility settings in the U.S. and potentially Europe and Asia, driven by severe infections resistant to standard antibiotics.

  2. How does Xerava compare pricing-wise to other antibiotics?
    It is priced higher than broad-spectrum antibiotics like meropenem but comparable to newer β-lactam/β-lactamase inhibitor combinations.

  3. What factors could cause Xerava prices to decline?
    Introduction of generics, increased competition, or regulatory pressures reducing reimbursement levels.

  4. Are off-label uses impacting the market?
    Off-label uses are limited but could expand demand if supported by further clinical evidence.

  5. What is the outlook for Xerava in terms of profitability for manufacturers?
    The outlook remains positive due to limited competition and growing resistance-driven demand, but price erosion remains a risk over the medium term.

References

[1] U.S. Food and Drug Administration. (2019). FDA approvals for Xerava.
[2] IQVIA. (2023). Hospital antimicrobial sales report.
[3] Wolters Kluwer. (2022). Antibiotics market analysis.
[4] Medicare Reimbursement Policy. (2023). Reimbursement frameworks for antimicrobials.
[5] MarketLine. (2022). Global antimicrobial drugs industry profile.

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