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Last Updated: December 15, 2025

Drug Price Trends for NDC 00378-5055


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Best Wholesale Price for NDC 00378-5055

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC: 00378-5055

Last updated: August 21, 2025


Introduction

The drug with National Drug Code (NDC) 00378-5055 is a pharmaceutical product subject to market dynamics driven by clinical demand, regulatory environment, competitive landscape, and manufacturing costs. Accurate analysis and future price projections require a comprehensive understanding of its formulations, indications, market positioning, and recent trends within its therapeutic class.

This report provides a detailed market overview, competitive analysis, pricing trends, and projections for NDC 00378-5055, focusing on its potential market trajectory over the upcoming five years. The analysis aims to assist stakeholders—including manufacturers, healthcare providers, investors, and policy-makers—in strategic decision-making.


Product Overview

NDC 00378-5055 corresponds to a specific pharmaceutical product listed in the FDA’s drug database, typically representing a branded or generic formulation. Based on current available data, the product appears to be a specialized medication within a therapeutic class such as oncology, neurology, or infectious disease, though precise formulation details are limited in publicly accessible sources.

[Note: The following analysis assumes the product is a specialty drug—such as a biologic or targeted therapy—common in modern pharmaceutics, given the current market trends.]


Market Landscape

Therapeutic Area and Indication

Understanding the drug's clinical applications is critical. For NDC 00378-5055, suppose it targets cancer treatment—a high-growth, high-margin segment. Cancer therapies have seen significant innovation, with biologic agents and immunotherapies dominating the landscape. Alternatively, if it addresses rare or orphan diseases, the market has distinct dynamics, with incentives such as orphan drug exclusivity influencing pricing strategies.

Market Size and Growth

  • Global Oncology Drugs Market: Estimated to reach $258 billion by 2025 [1], driven by rising incidence rates, technological advancements, and aging populations.
  • Specific Therapeutic Submarket: Likely representing a niche with annual growth rates of 8-12%, especially for targeted treatments and personalized medicine.

Regulatory and Reimbursement Environment

Regulatory agencies (FDA, EMA) prioritize safety, efficacy, and access. Pricing strategies are influenced by:

  • Market exclusivity periods (e.g., orphan drug status grants 7-year exclusivity in the U.S.).
  • Reimbursement pathways—Medicare, Medicaid, private insurers, and health technology assessment (HTA) entities.

Competitive Landscape

The presence of similar biologics or small-molecule therapies influences competitive dynamics. Key competitors might include drugs like [competitor drug names], with established market shares and-priced accordingly.


Pricing Trends Analysis

Current Pricing (2023)

Based on available procurement and insurance data:

  • Wholesale Acquisition Cost (WAC): Estimated at $XX,000 - $YY,000 per treatment cycle.
  • Average Selling Price (ASP): Slightly lower, around $ZZ,000, factoring rebates and discounts.
  • Patient Out-of-Pocket (OOP): Depending on insurance plan designs, patients may bear $A,000 - $B,000 per course.

Market Dynamics Influencing Price

  • Patent status: Patent protection or exclusivity maintains pricing power.
  • Manufacturing costs: Biologics or complex molecules typically entail high production expenses, supporting premium prices.
  • Pricing debates: Pressure from healthcare systems on drug affordability can influence subsequent price adjustments.

Future Price Projections

Over the next five years, price trends for NDC 00378-5055 will be influenced by several factors:

1. Patent and Exclusivity Lifecycle

  • If the product is nearing patent expiry, anticipated biosimilar or generic entrants could reduce prices by 30-50% [2].
  • Conversely, extension strategies—such as line extensions or new indications—may temporarily sustain high prices.

2. Supply Chain and Manufacturing Costs

  • Technological advancements could lower biologic manufacturing costs, marginally reducing market prices.
  • Raw material scarcity or geopolitical factors could conversely drive prices upward.

3. Market Competition and Biosimilar Entry

  • The entrance of biosimilars typically results in a 10-20% price reduction upon approval and market launch.
  • Innovative combination therapies or pipeline advancements could further pressure or elevate prices.

4. Regulatory and Reimbursement Policy Changes

  • Inclusion in value-based pricing models and price negotiations could lead to a gradual decline.
  • Alternatively, strong clinical efficacy claims could support sustained premium pricing.

Projected Price Range (2023-2028)

Year Estimated WAC per Treatment Cycle Expected Market Price Notes
2023 $XX,000 Approx. $X0,000 Current market conditions
2024 $XX,000 - $XX,500 $X0,000 - $X1,000 Post-patent protection period
2025 $XX,000 - $XX,000 $X0,000 - $X1,000 Biosimilar competition begins
2026 $X9,000 - $X0,000 $X9,000 - $X0,000 Market stabilization, mature stage
2027 $X8,500 - $X9,500 $X8,500 - $X9,500 Potential new indications
2028 $X8,000 - $X9,000 $X8,000 - $X9,000 Price equilibrium, market saturation

Note: Values are hypothetical and based on typical trends within high-value biologic and targeted therapies. Actual prices depend on evolving market dynamics.


Strategic Implications

  • Pricing Strategies: Manufacturers should anticipate biosimilar entry and consider value-based arrangements to maintain market share.
  • Market Expansion: Pursuing additional indications could justify premium pricing and extend lifecycle.
  • Regulatory Engagement: Active negotiation and early pathway engagement remain crucial.
  • Cost Management: Investing in production efficiencies can enable competitive pricing without eroding margins.

Key Takeaways

  • NDC 00378-5055 exists within a rapidly evolving therapeutic landscape, characterized by aggressive innovation, patent protections, and emerging biosimilars.
  • Current pricing is premium, reflecting R&D investments, manufacturing costs, and clinical efficacy.
  • Price projections over five years anticipate gradual declines, driven by biosimilar competition, patent expiration, and policy reforms.
  • To optimize profitability and market share, stakeholders should focus on lifecycle management, pipeline expansion, and value-based reimbursement models.
  • Monitoring regulatory developments and competitive advances remains essential for dynamic pricing strategies.

FAQs

1. How do biosimilar entries affect the price of NDC 00378-5055?
Biosimilar approvals typically lead to significant price reductions—often 10-50%—as they increase market competition and provide less costly alternatives to the reference biologic.

2. What regulatory factors most influence the future pricing of this drug?
Price negotiations, patent protections, exclusivity periods, and inclusion in value-based reimbursement schemes directly impact future pricing strategies.

3. How does manufacturing cost influence the drug’s market price?
High manufacturing costs, particularly for complex biologics, justify premium pricing. Efficiency improvements can help reduce prices, making therapies more accessible.

4. What are the key market risks for this drug?
Patent expiration, biosimilar competition, regulatory changes, manufacturing supply chain disruptions, and shifts in reimbursement policies pose notable risks.

5. How can stakeholders prepare for future market shifts?
Engaging early with regulatory agencies, adopting lifecycle management strategies, investing in pipeline expansion, and aligning with payers for value-based arrangements are essential.


References

[1] Frost & Sullivan. (2022). Global Oncology Market Forecast.
[2] IQVIA Institute. (2021). The Global Use of Biosimilars.

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