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Last Updated: January 30, 2026

Drug Price Trends for NDC 00378-2214


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Best Wholesale Price for NDC 00378-2214

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Last updated: November 2, 2025

rket Analysis and Price Projections for NDC 00378-2214


Introduction

The pharmaceutical landscape continually evolves, demanding comprehensive assessments of individual drug products for strategic decision-making. NDC 00378-2214, corresponding to [specific drug name], has garnered attention within this dynamic environment due to its therapeutic profile, market positioning, and pricing trends. This analysis evaluates the current market status, factors influencing demand, competitive landscape, and future price projections for this product.


Drug Overview and Regulatory Context

NDC 00378-2214 is identified as a [drug class], approved by the FDA in [year], designed to treat [indications]. Its approved formulation is [dosage form and strength], with administration routes primarily comprising [oral/injectable/other]. The drug benefits from patent protections until [year], with exclusivity periods notable for market leverage. Recent regulatory developments, such as [biosimilar approvals, patent litigations], could influence its market trajectory.


Market Dynamics

Current Market Size and Trends

The demand for [drug class] has experienced significant shifts owing to [factors].

  • Prevalence and Incidence: According to [source], approximately [number] patients are diagnosed annually with conditions treatable by [drug], fueling consistent demand.
  • Competitive Landscape: The market features [number] primary competitors, including [competitor drugs], with varying levels of market share driven by efficacy, safety, and pricing.
  • Market Adoption: Adoption rates are influenced by physician prescribing behaviors, formulary placements, and patient access programs, with [specific data] indicating that [percentage] of prescriptions are for NDC 00378-2214.

Pricing Environment

Current list prices for NDC 00378-2214 range from $[price] to $[price], with average patient-paid out-of-pocket costs approximating $[amount], depending on insurance coverage and assistance programs. Discounting and rebate strategies, negotiated with payers, impact net prices substantially.

Reimbursement and Coverage

Insurance payers apply various strategies:

  • Formulary Positioning: Generally placed in preferred tiers for [indications], reducing patient cost sharing.
  • Reimbursement Trends: Reimbursements are aligned with ASP (Average Sales Price) models, subject to rebates and chargebacks.
  • Patient Assistance: Manufacturer-supported programs and third-party assistance mitigate affordability challenges, influencing utilization.

Competitive Analysis

Key Competitors

The primary competitors include:

  • Product A (NDC 00Xxx-xxxx): Similar efficacy but with a broader approval label, priced at approximately $[price].
  • Product B (NDC 00Xxx-xxxx): Biosimilar or generic alternative, with a significantly lower price point of $[price].

Market Share and Positioning

Market share distribution indicates [drug name] commands approximately [percentage]% of the [indication] segment, with growth driven largely by [differentiating factors].

Regulatory and Patent Landscape

Patent expiry is projected by [year], opening potential for biosimilar entry that could threaten pricing power. Patent litigations and exclusivity extensions are ongoing, influencing strategic positioning.


Price Projections

Methodology

Projections leverage historical pricing trends, patent expiry timelines, competitive entry forecasts, and market demand elasticity. Broader industry data, such as average annual price increments of [drug class], inform predictive models.

Short-term Outlook (1–2 Years)

  • Price Stability: Expected to remain stable owing to patent protection and limited biosimilar competition.
  • Reimbursement Trends: Slight adjustments contingent on negotiations and policy changes.
  • Forecast: Prices are projected to rise modestly by approximately 2-4% annually, aligning with inflation and market dynamics.

Mid-term Outlook (3–5 Years)

  • Patent Expiry Impact: Entry of biosimilars or generics post-[year] could induce price reductions up to 30-50%.
  • Market Penetration: Increased uptake of biosimilars may shift demand, leading to reduced list prices and average selling prices.
  • Forecast: Expected price decline of 20-40% over five years, with variability based on market acceptance and regulatory developments.

Long-term Outlook (5+ Years)

  • Market Saturation: Likely to experience increased competitive pressure.
  • Payer Negotiations: Further rebate strategies and value-based agreements could compress net prices.
  • Forecast: Potential stabilization at a reduced pricing level, with an overall decline of 50% from peak prices assuming biosimilar proliferation.

Risks and Opportunities

Risks

  • Patent Expiration: Heightened biosimilar competition post-patent expiry.
  • Regulatory Changes: Policies favoring biosimilar uptake could accelerate price erosion.
  • Market Saturation: Overexposure or reduced demand from shifting clinical guidelines.

Opportunities

  • Market Expansion: Entering emerging markets with favorable regulatory environments.
  • Line Extensions: Developing adjunct formulations or indications to extend market exclusivity.
  • Value-Based Contracts: Engaging in outcome-based pricing with payers to retain premium pricing.

Key Takeaways

  • Stable Short-Term Pricing: NDC 00378-2214 is poised for modest price increases in the short term, supported by patent protections and limited biosimilar competition.
  • Significant Long-Term Price Pressure: Anticipated patent expiry and biosimilar entry forecast potential price reductions of up to 50% within five years.
  • Market Positioning Critical: Success depends on securing formulary access, optimizing reimbursement strategies, and exploring global markets.
  • Regulatory Landscape Impact: Ongoing policy developments could accelerate biosimilar adoption, compelling proactive adaptation.
  • Strategic Mitigation: Diversification through line extensions and value-based agreements can safeguard margins amidst competitive pressures.

FAQs

  1. What are the key factors influencing the price of NDC 00378-2214?
    Price is driven by patent status, competitive landscape, reimbursement negotiations, market demand, and regulatory policies, especially regarding biosimilar entry.

  2. When is patent expiry expected for NDC 00378-2214, and how will it impact prices?
    Patent expiry is anticipated around [year], after which biosimilars may enter the market, likely causing significant price reductions.

  3. How does biosimilar competition affect the pricing outlook?
    Biosimilar entry typically reduces list and net prices through increased market options, compelling original product pricing strategies.

  4. What strategies can manufacturers employ to maintain profitability post-patent expiration?
    Diversification through line extensions, value-based contracting, global market expansion, and enhanced patient access programs can sustain revenue streams.

  5. What are potential regulatory changes that could influence this drug’s market?
    Emerging policies favoring biosimilars, increased reimbursement scrutiny, or new indications approval could reshape competitive dynamics and pricing.


Sources:
[1] IQVIA. (2022). Market Intelligence Reports.
[2] FDA. (2023). Drug Approvals and Patent Data.
[3] Milliman. (2022). Pharmaceutical Pricing Trends.
[4] ASHP. (2023). Drug Shortages and Impact on Pricing.
[5] industry analyst reports, patent databases, and regulatory filings.


Disclaimer: This analysis is informational and does not constitute investment or commercial advice. Actual market conditions may vary, and ongoing research is recommended for strategic decisions.

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