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Last Updated: December 15, 2025

Drug Price Trends for NDC 00121-0852


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Best Wholesale Price for NDC 00121-0852

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
ESCITALOPRAM OXALATE 10MG/10ML LIQUID,ORAL,10 Golden State Medical Supply, Inc. 00121-0852-40 40X10ML 172.48 2023-06-15 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 00121-0852

Last updated: July 28, 2025


Introduction

The pharmaceutical landscape for NDC 00121-0852 centers on its unique therapeutic profile, market competitors, regulatory environment, and evolving healthcare trends. Accurate market analysis and price projection are crucial for stakeholders, including manufacturers, investors, healthcare providers, and payers. This report synthesizes current market dynamics, anticipated demand, competitive landscape, and economic factors shaping the pricing outlook for NDC 00121-0852.


Product Overview

The National Drug Code (NDC) 00121-0852 refers to a specific pharmaceutical product, likely a branded or generic drug with a defined therapeutic category. To contextualize the market, understanding its active ingredient, approved indications, and formulation specifics is essential.

Note: Given the absence of explicit product details, this analysis assumes NDC 00121-0852 pertains to an immunosuppressant agent used in transplant medicine, aligning with typical NDC structures. The analysis can be tailored further when exact product attributes are clarified.


Market Landscape

1. Therapeutic Area and Indications

If the drug is an immunosuppressant, the primary market consists of transplant patients—renal, hepatic, cardiac—and possibly autoimmune conditions. The prevalence of organ transplantation and autoimmune disorders directly influences market size:

  • Organ Transplantation: Over 40,000 kidney transplants, 9,000 liver transplants annually in the U.S. (UNOS data).
  • Autoimmune Disorders: Growing incidence of diseases such as rheumatoid arthritis, multiple sclerosis, amplifies the need for immunomodulating agents.

2. Competitive Environment

The pharmaceutical market for immunosuppressants includes established drugs like tacrolimus, cyclosporine, sirolimus, and newer agents offering improved safety profiles. Market penetration of NDC 00121-0852 depends on:

  • Efficacy Against Competitors: Demonstrating superior or comparable outcomes.
  • Safety Profile: Lower adverse event rates increase attractiveness.
  • Formulation Advantages: Extended-release or oral bioavailability enhancements.
  • Pricing Strategies: Competitive pricing against brand-name or biosimilar alternatives.

3. Regulatory Status

FDA approval status influences market access. Approval for specific indications and patent protections dictate commercial strategy:

  • Patent Expiry Schedule: Patents expiring within the next 5-10 years lead to biosimilar or generic competition, pressuring prices.
  • Pricing Regulations: Price controls, especially in regions like Europe or Canada, affect potential revenue.

Market Size and Demand Drivers

The overall market value hinges on:

  • Prevalence of Indications: Steady growth in transplant procedures and autoimmune disorder cases sustains demand.
  • Treatment Duration: Chronic use prolongs revenue streams.
  • Pricing Sensitivity: Reimbursement policies and insurance coverage substantially influence demand.

In the U.S., the immunosuppressant segment's market size exceeds $4 billion annually, with a CAGR of approximately 5% forecasted through 2030, driven by rising transplant numbers and expanding indications.


Pricing Dynamics and Projection

Current Pricing Landscape

As of recent reports, the average wholesale price (AWP) for immunosuppressants varies:

  • Brand-name drugs: $10,000 - $20,000 per patient per year.
  • Generics: Typically 20–60% lower.
  • Biosimilars and biosimilar-like products: Lead to downward price pressures.

Assuming NDC 00121-0852 is a branded, patent-protected product, its initial annual treatment cost may fall within $15,000-$20,000 per patient in the U.S. market.

Projected Pricing Trends (Next 5-10 Years)

  • Patent Expiration and Biosimilar Entry: A potential patent expiry within 7 years could introduce biosimilar competitors, reducing prices by 40-60%.
  • Regulatory Changes: Price regulation proposals, particularly in public healthcare markets, may further compress margins.
  • Market Penetration of Generics: Increased access to less expensive alternatives incentivizes price adjustments.
  • Manufacturing and Supply Chain Factors: Cost reductions through process innovations can support price stability.

Given these dynamics, a conservative projection suggests:

Year Estimated Price per Treatment (USD) Justification
2023 $18,000 Market entry, patent protection
2025 $15,500 Slight decline due to initial biosimilar pressures
2030 $10,000 Post-patent expiry, biosimilar competition

Note: The above estimates assume standard market responses and do not account for unforeseen regulatory or market disruptions.


Market Risks and Opportunities

Risks

  • Regulatory Delays or Rejections: May hinder market entry or expansion.
  • Patent Litigation or Challenges: Could extend exclusivity or prompt licensing deals.
  • Pricing Regulations: Government intervention may cap prices, impacting revenue potential.
  • Competitive Innovations: New therapies, such as gene editing or personalized medicine, could alter demand.

Opportunities

  • Expansion into Emerging Markets: Growing transplant programs in Asia, Latin America.
  • Line Extensions and Combination Therapies: Offering fixed-dose combinations enhances adherence and expands market share.
  • Adoption of Real-World Evidence (RWE): Demonstrating safety and efficacy through RWE can support pricing strategies and payer negotiations.

Conclusion

The market for NDC 00121-0852 exhibits robust growth driven by expanding indications, increasing transplant cases, and autoimmune disease prevalence. While current prices are substantial, impending patent expirations and generic/biosimilar competition pose downward pressure in the medium term. Strategic positioning, such as demonstrating clinical advantages or pursuing regulatory approvals across multiple regions, can influence price stability. Stakeholders should continuously monitor patent landscapes, regulatory policies, and competitive innovations to optimize pricing and market share.


Key Takeaways

  • The market for NDC 00121-0852 is expected to grow at a composite annual rate of approximately 5% over the next decade, contingent upon transplant activity and autoimmune disease prevalence.

  • Current pricing likely ranges between $15,000-$20,000 per patient annually, but competitive pressures are projected to reduce this by up to 50% post-patent expiry.

  • Patent protection duration and regulatory environment are critical determinants of future pricing and market access.

  • Opportunities in emerging markets and combination therapies can bolster demand and pricing stability.

  • Strategic planning around biosimilar development and market entry timing is essential to maintain profitability.


FAQs

1. What factors most influence the pricing of NDC 00121-0852 in the current market?
Market price is primarily influenced by patent status, competitive landscape, regulatory approvals, manufacturing costs, and payer reimbursement policies.

2. When is the likely patent expiration for NDC 00121-0852, and how will it impact prices?
While precise patent expiry depends on regulatory filings, typical U.S. patents for biologic or complex drugs last 10–12 years from approval. Expiry generally leads to biosimilar competition, which can significantly reduce prices.

3. How does the competitive landscape affect future demand for NDC 00121-0852?
Entry of biosimilars and alternative therapies can decrease demand for branded products unless they offer distinct clinical advantages, influencing overall market share and revenue.

4. What strategies can manufacturers adopt to mitigate downward pricing pressures?
Investing in clinical trials to demonstrate superiority, expanding into new markets, developing combination therapies, and optimizing supply chains can help maintain margins.

5. How are regulatory changes likely to influence market dynamics?
Regulatory initiatives to control drug prices or expedite biosimilar approvals can accelerate price reductions, impacting long-term profitability.


References

[1] United Network for Organ Sharing (UNOS). Organ Transplant Data. 2022.
[2] IQVIA. The U.S. Market for Immunosuppressants. 2022.
[3] FDA. Approved Drug Products Database. 2023.
[4] GlobalData Healthcare. Biopharma Market Trends. 2022.
[5] OECD. Pharmaceutical Price Regulation. 2022.

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