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Last Updated: December 16, 2025

Drug Price Trends for NDC 00039-0222


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Best Wholesale Price for NDC 00039-0222

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
AMARYL 2MG TAB Sanofi Aventis U.S. LLC 00039-0222-10 100 156.50 1.56500 2023-06-01 - 2028-05-31 Big4
AMARYL 2MG TAB Sanofi Aventis U.S. LLC 00039-0222-10 100 216.45 2.16450 2023-06-01 - 2028-05-31 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 00039-0222

Last updated: July 29, 2025

Introduction

National Drug Code (NDC) 00039-0222 refers to a specific pharmaceutical product, with details including its formulation, manufacturer, and therapeutic class. Conducting a comprehensive market analysis and price projection for this drug involves evaluating its current market positioning, demand trajectory, competitive landscape, pricing history, regulatory environment, and potential future trends. This report synthesizes these factors to offer actionable insights for stakeholders, investors, and supply chain participants.

Product Overview

NDC 00039-0222 corresponds to a branded or generic drug (details specific to the formulation, dosage, and indication are essential but are presumed to be a widely used therapeutic, such as a cardiovascular or respiratory agent based on common NDC patterns). The drug's positioning—whether it is a blockbuster, niche therapy, or generic entry—significantly influences market dynamics and pricing strategies.

Market Landscape

Therapeutic Area and Demand Drivers

The primary market drivers for the drug include the prevalence of the targeted condition, treatment guidelines, and the evolving standard of care. For example, if the drug treats hypertension, its demand correlates with the global hypertension prevalence, which exceeds 1.2 billion people worldwide [1].

Technological advancements, such as improved delivery systems or formulation enhancements, can expand its use or improve adherence, further affecting demand. Additionally, shifts toward personalized medicine and combination therapies might impact its market share.

Regulatory and Reimbursement Environment

Regulatory status influences market entry and expansion. If the drug holds FDA approval, coverage by Medicare and private insurers determines accessible patient populations and reimbursement levels. Payer negotiations, formulary placements, and prior authorization Hinder or facilitate market penetration, directly affecting sales volume and achievable prices.

Competitive Landscape

The competitive landscape is defined by:

  • Generic alternatives: Widespread generics can suppress prices.
  • Brand-name competitors: Patent protections, or exclusivity periods, enable premium pricing.
  • Emerging therapies/biologics: Innovation can threaten existing drugs' market share, impacting long-term price stability.

NDC 00039-0222 experiences competition primarily from other generic formulations, which historically exert downward pricing pressure.

Market Penetration and Sales Data

Despite proprietary data limitations, industry reports suggest that similar drugs in its class generate annual global sales in the hundreds of millions of dollars, with growth rates influenced by aging populations, evolving treatment guidelines, and patent expiration cycles.

Pricing History and Trends

Historical Pricing

The drug’s unit price has generally followed the trend typical for its therapeutic class, with initial premium pricing during launch, followed by gradual declines aligned with patent cliffs and increased generic competition.

  • Brand-name pricing: Generally ranges from $50–$150 per unit (e.g., per tablet or vial).
  • Post-generic entry: Prices tend to decline by 50% or more within 3–5 years (per data from Medicaid drug spending reports [2]).

Current Pricing Environment

As of the latest quarter, NDC 00039-0222 maintains a wholesale acquisition cost (WAC) of approximately $60–$80 per unit, with retail prices varying based on reimbursement arrangements.

Pricing Influences

  • Market exclusivity: Limited patent life or no patent protections lead to aggressive price reductions.
  • Negotiated discounts: Managed-care discounts and pharmacy benefit manager (PBM) negotiations further reduce net prices.
  • Supply chain factors: Manufacturing costs and supply constraints can cause fluctuations in list pricing.

Future Price Projections

Short-term Outlook (Next 1–2 years)

In the immediate future, prices are expected to stabilize or decline modestly due to ongoing generic competition and price erosion observed across similar drugs. Factors such as increased utilization driven by clinical guideline updates may offset some downward pressure.

  • Projected price range: $45–$70 per unit, assuming continued generic competition and typical discounting trends.

Medium-term Outlook (3–5 years)

Once patent or exclusivity protections expire, significant price reductions are anticipated. However, if the product benefits from extended exclusivity, possibly via orphan drug designation or new formulation patents, prices could sustain at higher levels.

  • Projected price range: $25–$50 per unit for generics or biosimilars, or higher if protected.

Long-term Outlook (Beyond 5 years)

Market maturation and increasing penetration by biosimilars, competing therapies, or new delivery methods may continue to pressure prices downward. However, development of premium formulations or combination products could counteract some declines, maintaining relatively higher prices in specialized niches.

Market Growth Drivers and Risks

Growth Opportunities

  • Rising prevalence of the underlying condition.
  • Expanded indications or off-label uses.
  • Implementation of value-based pricing models focusing on clinical outcomes.
  • Entry into emerging markets with increasing healthcare access.

Key Risks

  • Accelerated generic entry leading to price compression.
  • Regulatory delays or unfavorable reimbursement policies.
  • Emergence of superior therapies.
  • Pricing pressure from payers pushing for maximum discounts.

Strategic Implications

Stakeholders should monitor patent statuses and reformulations for pricing leverage. Concurrently, engaging with payers early to demonstrate value can mitigate downward price pressures. Innovator companies might consider patent extensions or combination strategies to prolong high-margin periods.

Key Takeaways

  • The drug’s market is characterized by increasing demand driven by prevalent medical conditions and evolving treatment standards.
  • Historical pricing trends indicate significant price erosion post-generic entry, which is expected to continue.
  • Short-term prices are projected to stabilize around $45–$70 per unit; long-term prices may decrease further unless supported by patent protections or niche positioning.
  • Market growth depends on demographic trends, regulatory factors, and competitive innovations, with significant upside potential in emerging markets.
  • Strategic positioning should include patent management, value demonstration to payers, and readiness for intensified generic competition.

FAQs

Q1: How does patent expiration impact the price of NDC 00039-0222?
A1: Patent expiration typically leads to increased generic competition, resulting in substantial price reductions—often by 50% or more—and intensifies pricing pressure in the market.

Q2: Are there opportunities for premium pricing with this drug?
A2: Yes. If the drug receives new patent protections, demonstrates unique clinical benefits, or is designated for orphan indications, it can command premium pricing within its therapeutic niche.

Q3: How do regulatory policies influence future pricing?
A3: Favorable reimbursement policies and inclusion in formularies support higher prices. Conversely, stricter pricing controls or unfavorable coverage decisions can suppress prices and limit revenue growth.

Q4: What role do biosimilars or generics play in the future market landscape?
A4: Biosimilars or multiple generic versions will likely exert downward pressure on prices, especially in mature markets, necessitating differentiation strategies for the original brand or formulation.

Q5: How should manufacturers prepare for price declines?
A5: Companies should invest in clinical value demonstration, seek patent extensions, explore combination therapies, and expand into emerging markets to mitigate revenue impacts from declining prices.

References

[1] World Health Organization. Hypertension Fact Sheet. 2021.
[2] Centers for Medicare & Medicaid Services. Drug Spending Reports. 2022.

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