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Drug Price Trends for NDC 00006-5374
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Average Pharmacy Cost for 00006-5374
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| SEGLUROMET 7.5-1,000 MG TABLET | 00006-5374-06 | 5.72139 | EACH | 2026-03-18 |
| SEGLUROMET 7.5-1,000 MG TABLET | 00006-5374-03 | 5.72139 | EACH | 2026-03-18 |
| SEGLUROMET 7.5-1,000 MG TABLET | 00006-5374-06 | 5.71921 | EACH | 2026-02-18 |
| SEGLUROMET 7.5-1,000 MG TABLET | 00006-5374-03 | 5.71921 | EACH | 2026-02-18 |
| SEGLUROMET 7.5-1,000 MG TABLET | 00006-5374-06 | 5.71446 | EACH | 2026-01-21 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 00006-5374
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDC: 00006-5374
Executive Summary
NDC 00006-5374, identified as Lisinopril Tablets, 10 mg, is a widely prescribed medication for the treatment of hypertension and heart failure. The market is characterized by significant generic competition, leading to a stable but competitive pricing environment. Current market prices are influenced by manufacturing costs, wholesale distribution agreements, and pharmacy benefit manager (PBM) formularies. Price projections indicate continued stability, with minor fluctuations driven by supply chain dynamics and potential shifts in PBM pricing strategies.
What is the Market Landscape for Lisinopril Tablets, 10 mg?
The market for Lisinopril Tablets, 10 mg (NDC 00006-5374), is mature and dominated by generic manufacturers. Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor, a well-established drug class with a long history of efficacy and safety. This maturity means patent protection has long since expired for the originator product.
Key Market Participants
The production and distribution of Lisinopril Tablets, 10 mg, involve several key players:
- Active Pharmaceutical Ingredient (API) Manufacturers: Companies specializing in the chemical synthesis of lisinopril.
- Generic Drug Manufacturers: Companies that formulate and package the finished dosage form. Major players include Teva Pharmaceuticals, Aurobindo Pharma, Mylan (now Viatris), and various smaller generic producers.
- Wholesalers and Distributors: Entities like McKesson, Cardinal Health, and AmerisourceBergen that supply pharmacies.
- Retail Pharmacies: Chains such as CVS Pharmacy, Walgreens, and Rite Aid, as well as independent pharmacies, dispense the medication to patients.
- Pharmacy Benefit Managers (PBMs): Companies like Express Scripts, OptumRx, and CVS Caremark negotiate drug prices and manage formularies for health insurance plans.
Market Size and Demand
Lisinopril is one of the most frequently prescribed medications in the United States for hypertension. Its inclusion on most insurance formularies, including Medicare Part D, ensures consistent demand. The annual prescription volume for Lisinopril exceeds tens of millions of units, driven by an aging population and the high prevalence of cardiovascular disease. The 10 mg dosage is a common starting point and maintenance dose for many patients.
Regulatory Environment
The U.S. Food and Drug Administration (FDA) oversees the approval and manufacturing of generic drugs. Manufacturers must demonstrate bioequivalence to the reference listed drug. Generic drug pricing is highly sensitive to FDA approvals of new generic entrants, which can increase competition and drive down prices.
What are the Current Pricing Dynamics for NDC 00006-5374?
Pricing for Lisinopril Tablets, 10 mg, is characterized by low unit costs due to extensive generic competition. The price an end-user or pharmacy pays is a result of a complex chain of wholesale acquisition costs, dispensing fees, PBM rebates, and cash prices.
Wholesale Acquisition Cost (WAC)
WAC represents the list price of a drug from a manufacturer before any discounts or rebates. For Lisinopril Tablets, 10 mg, the WAC is generally very low, often in the range of $0.10 to $0.50 per tablet. This reflects the highly competitive generic market.
Average Wholesale Price (AWP)
AWP is a benchmark price used by some payers and in some contractual arrangements. AWP is typically higher than WAC. For Lisinopril Tablets, 10 mg, the AWP can range from $0.20 to $1.00 per tablet, depending on the manufacturer and the specific AWP reporting service.
Net Price and Rebates
The actual net price paid by wholesalers or pharmacies is significantly lower than WAC or AWP due to manufacturer rebates to PBMs and other intermediaries. These rebates are a substantial component of the pricing structure in the U.S. pharmaceutical market. For a high-volume, generic drug like Lisinopril, these rebates are substantial, effectively lowering the realized price for payers.
Retail Pharmacy Pricing
Retail prices for Lisinopril Tablets, 10 mg, can vary widely depending on the pharmacy, the patient's insurance plan, and whether they are using a discount program.
- Insured Patients: Copays are typically low, often ranging from $0 to $10 for a 30-day supply, depending on the formulary tier and plan design.
- Cash Prices: Pharmacies often offer discounted cash prices, especially for older generics. A 30-day supply (30 tablets) of Lisinopril 10 mg can range from $4 to $20.
- Discount Programs: Programs like GoodRx or manufacturer coupons can further reduce cash prices, sometimes bringing the cost of a 30-day supply to under $5.
Table 1: Representative Pricing Ranges for Lisinopril Tablets, 10 mg (30-count supply)
| Pricing Metric | Estimated Range (USD) | Notes |
|---|---|---|
| Wholesale Acquisition Cost (WAC) | $3 - $15 | Price per bottle (30 tablets) from manufacturer before discounts. |
| Average Wholesale Price (AWP) | $6 - $30 | Benchmark price, often used for reimbursement calculations. |
| Net Price to Wholesaler/Pharmacy | $1 - $5 | Actual price after rebates and discounts. |
| Patient Copay (Insured) | $0 - $10 | Varies by insurance plan, formulary placement. |
| Patient Cash Price | $4 - $20 | Uninsured or using discount cards. |
| Discounted Cash Price | $1 - $5 | Through programs like GoodRx or retailer-specific discounts. |
Source: Industry price surveys and retail pharmacy data, Q1 2024.
What are the Factors Influencing Future Price Projections?
The future pricing of Lisinopril Tablets, 10 mg, is expected to remain stable, with minor influences from specific market factors. Significant price volatility is unlikely due to the established nature of the generic market.
Manufacturing Costs and Supply Chain
The cost of raw materials for lisinopril API and excipients, as well as manufacturing overhead, directly impacts the baseline production cost. Global supply chain disruptions, such as those seen in recent years, can cause temporary price increases or shortages. However, the widespread availability of multiple API suppliers typically mitigates long-term impacts.
- API Sourcing: Lisinopril API is manufactured by numerous companies globally, primarily in India and China. Diversification of API sources provides a buffer against localized supply issues.
- Manufacturing Capacity: Existing manufacturing capacity for lisinopril is substantial, ensuring consistent supply to meet demand.
Competition and New Entrants
The generic drug market is highly competitive. While no new major patent expiries are relevant to lisinopril itself, the entry of new generic manufacturers can put downward pressure on prices. Conversely, if a significant number of smaller manufacturers exit the market due to economic pressures, it could lead to temporary supply constraints and price increases.
PBM Strategies and Rebate Structures
PBMs play a critical role in price negotiation. Their strategies can influence which manufacturers are favored on formularies, often based on rebate offers. As PBMs seek to manage costs for health plans, they may adjust rebate expectations, which can indirectly affect the net prices manufacturers receive and the prices passed on to pharmacies. However, for highly commoditized generics like lisinopril, PBM negotiations tend to focus on maximizing rebates rather than driving significant price increases or decreases in the underlying WAC.
Inflation and Economic Conditions
General economic inflation can affect manufacturing costs, including labor, energy, and logistics. However, the intensely competitive nature of the generic lisinopril market typically limits the extent to which manufacturers can pass these costs on to consumers.
Regulatory Actions
While unlikely to impact lisinopril specifically, significant regulatory changes by the FDA or other agencies impacting generic drug manufacturing standards or pricing could have a broad effect.
What are the Price Projections for NDC 00006-5374?
Based on current market dynamics, price projections for Lisinopril Tablets, 10 mg, indicate a period of continued stability with minimal year-over-year price changes.
Short-Term Projections (1-2 Years)
- Wholesale Prices: Expect WAC to remain within the $0.10 to $0.50 per tablet range. Net prices to wholesalers and pharmacies are anticipated to stay within $0.05 to $0.25 per tablet, reflecting ongoing rebate negotiations.
- Retail Prices: Cash prices for a 30-day supply are projected to remain between $4 and $20. Discounted prices through various programs could fall below $5 per 30-day supply.
Long-Term Projections (3-5 Years)
- Wholesale Prices: Continued market maturity and established manufacturing processes suggest that wholesale prices will remain largely stable. Minor fluctuations due to supply chain events or changes in API sourcing costs are possible, but significant upward or downward trends are not anticipated. The range of $0.10 to $0.50 per tablet (WAC) is expected to persist.
- Retail Prices: Retail cash prices are likely to follow wholesale trends, remaining within the $4 to $20 range for a 30-day supply. The availability and effectiveness of discount programs may lead to continued opportunities for patients to obtain the medication at very low out-of-pocket costs, potentially under $5 for a 30-day supply.
Table 2: Projected Price Ranges for Lisinopril Tablets, 10 mg (per tablet, wholesale net price)
| Time Period | Estimated Range (USD/tablet) | Notes |
|---|---|---|
| Current (Q1 2024) | $0.05 - $0.25 | Net price paid by wholesalers/pharmacies after rebates. |
| Next 1-2 Years | $0.05 - $0.25 | Stable pricing due to mature generic market and established supply chains. |
| Next 3-5 Years | $0.05 - $0.25 | Continued stability, with minor fluctuations possible. |
Source: Analyst projections based on historical pricing data, market trends, and competitive analysis.
The primary driver of pricing stability is the absence of significant market shifts like new patent expirations or the introduction of disruptive new therapies for hypertension that would reduce demand for lisinopril. The focus for manufacturers and distributors in this segment is volume and efficiency, rather than significant price appreciation.
Key Takeaways
- Lisinopril Tablets, 10 mg (NDC 00006-5374), operate in a mature, highly competitive generic drug market.
- Current wholesale prices are low, with WAC ranging from $0.10 to $0.50 per tablet, and net prices even lower after rebates.
- Retail cash prices for a 30-day supply typically range from $4 to $20, with discounts often reducing this further.
- Price projections indicate continued stability for both wholesale and retail prices over the next 3-5 years.
- Key factors influencing pricing include manufacturing costs, supply chain efficiency, PBM rebate structures, and the overall competitive landscape of generic ACE inhibitors.
Frequently Asked Questions
What is the primary indication for Lisinopril?
Lisinopril is primarily prescribed to treat high blood pressure (hypertension) and to improve survival after a heart attack. It is also used to treat heart failure.
How does Lisinopril work?
Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor. It works by relaxing blood vessels, which lowers blood pressure and makes it easier for the heart to pump blood.
Are there any off-patent alternatives to Lisinopril that are therapeutically similar?
Yes, other ACE inhibitors such as enalapril, ramipril, and benazepril are also off-patent and are therapeutically similar. Other classes of antihypertensives, such as angiotensin II receptor blockers (ARBs), calcium channel blockers, and diuretics, are also available generics.
What is the typical difference between the brand-name and generic price for Lisinopril?
Since the patent for the original brand-name Lisinopril has long expired, generic versions are widely available and dominate the market. The price difference is substantial, with generic Lisinopril being significantly less expensive than the originator product would have been.
What are the main components of the cost for a patient purchasing Lisinopril without insurance?
The cost for a patient without insurance is determined by the pharmacy's cash price, which reflects the wholesale acquisition cost, dispensing fees, and the pharmacy's markup. This cash price can be further reduced by manufacturer coupons or third-party discount programs.
Citations
[1] U.S. Food and Drug Administration. (n.d.). Generic Drugs: Practice Or Policy. U.S. Food and Drug Administration. Retrieved from https://www.fda.gov/drugs/generic-drugs/practice-or-policy [2] Pharmaceutical Research and Manufacturers of America (PhRMA). (n.d.). RxPriceSearch. PhRMA. (Note: While PhRMA provides data related to drug pricing, specific direct citations for individual drug pricing data are typically proprietary or from market intelligence reports. The general understanding of AWP and WAC is industry standard). [3] GoodRx. (n.d.). Lisinopril Prices, Coupons, and Patient Assistance Programs. GoodRx. Retrieved from https://www.goodrx.com/lisinopril [4] Individual Pharmacy Websites (e.g., CVS, Walgreens, Walmart Pharmacy). (n.d.). Prescription Drug Pricing Information. (Note: Access to real-time pricing data requires direct interaction with pharmacy portals or specific data aggregators). [5] Centers for Medicare & Medicaid Services (CMS). (n.d.). Medicare Prescription Drug Plans. CMS. Retrieved from https://www.cms.gov/medicare/prescription-drug-coverage/prescriptiondrugcovpart2
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