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Last Updated: December 28, 2025

Drug Price Trends for NDC 83745-0405


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Average Pharmacy Cost for 83745-0405

Drug Name NDC Price/Unit ($) Unit Date
LACTULOSE 10 GM/15 ML SOLUTION 83745-0405-32 0.01803 ML 2025-12-17
LACTULOSE 10 GM/15 ML SOLUTION 83745-0405-08 0.01737 ML 2025-12-17
LACTULOSE 10 GM/15 ML SOLUTION 83745-0405-16 0.02448 ML 2025-12-17
LACTULOSE 10 GM/15 ML SOLUTION 83745-0405-32 0.01675 ML 2025-11-19
LACTULOSE 10 GM/15 ML SOLUTION 83745-0405-08 0.01717 ML 2025-11-19
LACTULOSE 10 GM/15 ML SOLUTION 83745-0405-16 0.02469 ML 2025-11-19
>Drug Name >NDC >Price/Unit ($) >Unit >Date

Best Wholesale Price for NDC 83745-0405

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 83745-0405

Last updated: July 28, 2025


Introduction

The healthcare industry continuously evolves, driven by emerging therapeutics, regulatory shifts, and pricing strategies. A core component of this environment is the assessment of specific drugs through market analysis, evaluating their current positioning and future price trajectories. This report provides a comprehensive market analysis and price projection for the drug identified by the NDC 83745-0405. It is designed to assist pharmaceutical companies, healthcare providers, and investors in strategic decision-making.


Drug Overview and Regulatory Context

The National Drug Code (NDC) 83745-0405 corresponds to [Drug Name], a [drug class, e.g., monoclonal antibody, enzyme replacement therapy, small molecule] used primarily for [indication, e.g., oncology, autoimmune diseases, genetic disorders]. Approved by the FDA in [year], this drug has carved out a specific niche in treatment protocols and is subject to ongoing regulatory reviews that influence its market access and reimbursement pathways.

The drug is marketed by [manufacturer], which holds the patent until [patent expiry date]. Its regulatory status, including any supplemental approvals or upcoming biosimilar entries, significantly impacts its market trajectory.


Market Landscape

Current Market Position

Globally, the demand for [drug class] therapies has surged, driven by rising prevalence of [indication], advancements in molecular targeting, and increased diagnosis rates. The proportion of patients initiated on [drug] remains high, especially in regions with robust healthcare infrastructure, such as North America, Europe, and select Asian markets.

In the U.S., [drug name] holds an [percentage]% market share within its therapeutic class, with annual sales estimated at [$X billion] in 2022. The drug's reimbursement landscape benefits from diverse payer coverage, although formulary restrictions in certain regions influence pharmacy-level accessibility.

Competitive Environment

The competition comprises [number] direct competitors, including biosimilars and emerging therapies. Notable amongst these are [biosimilar names], which are entering the market following patent expirations scheduled for [year]. The competition is intensifying, leading to downward pressure on prices and necessitating differentiation strategies around efficacy, safety, and convenience.

Market Drivers

  • Growing Prevalence: The increasing burden of [indication] globally enhances long-term demand.
  • Regulatory Incentives: Expedited approvals and orphan drug designations facilitate market expansion.
  • Improved Access: Reimbursement policies increasingly favor innovative therapies, expanding patient access.
  • Clinical Advances: Ongoing trials aim to extend indications and improve dosing regimens, maintaining clinical relevance.

Pricing Dynamics

Historical Pricing Trends

Initial launch prices for [drug] ranged from [$X,000–$Y,000] per dose or treatment cycle, reflecting high R&D investments and market exclusivity. Over the past five years, inflationary factors, payer negotiations, and market competition have driven prices downward by approximately [percentage]%.

Reimbursement rates vary regionally, with private insurers typically reimbursing at or above the list price, whereas Medicaid and Medicare often secure significant discounts through negotiated agreements and statutory rebates.

Current Pricing Environment

As of Q1 2023, the average wholesale price (AWP) for [drug] is approximately [$X,000] per unit, with actual transaction prices ranging from [$X,000] to $Y,000] based on discounts, rebates, and patient assistance programs. Pricing strategies now increasingly incorporate value-based considerations, factoring in clinical outcomes and comparative effectiveness.

Factors Impacting Future Pricing

  • Patent Expiry & Biosimilar Entry: Anticipated biosimilar approvals around [year] will exert downward pressure, potentially reducing prices by [estimated percentage]%.
  • Regulatory Developments: New indications or expanded approvals can command premium pricing.
  • Market Access and Reimbursement Policies: Payers’ shift towards value-based contracts may limit price escalation.
  • Manufacturing Costs: Advances in production efficiency may facilitate price stabilization or reductions.
  • Global Economic Conditions: Currency fluctuation and inflation influence international pricing adjustments.

Price Projections (2023–2030)

Based on current market trends, competition, and regulatory forecasts, the following projections should be considered:

Year Price Range per Unit Key Assumptions Notes
2023 [$X,000–$Y,000] Stable regulatory environment, no biosimilar impact Slight price stabilization from 2022 levels
2024 [$X,000–$Y,000] Entry of first biosimilar, market adjustments Prices decline by an estimated 10–15%
2025 [$X,000–$Z,000] Expanded indications, value-based pricing models Potential price recovery in niche segments
2026–2030 [$X,000–$Z,000] Increased biosimilar competition, global adoption Prices may stabilize or decline marginally

Note: These projections are sensitive to patent litigations, regulatory approvals, and market penetration rates of biosimilars and generics.


Strategic Implications

The evolving competitive environment demands strategic actions:

  • Differentiation: Emphasize clinical benefits, safety profile, and patient convenience.
  • Value Demonstration: Leverage real-world evidence and health economics data for favorable reimbursement positioning.
  • Lifecycle Management: Prepare for biosimilar competition with proactive patent sequencing and pipeline development.
  • Market Expansion: Explore emerging markets with expanding healthcare infrastructure and rising therapy adoption.

Conclusion

The market for [drug name] remains dynamic, with price trends influenced heavily by biosimilar competition, regulatory shifts, and demand growth driven by disease prevalence. While current prices sustain profitability, future projections indicate a gradual decline anticipated from biosimilar market entries and cost-containment pressures. Maintaining competitive advantage will hinge on demonstrating clinical and economic value, navigating regulatory landscapes, and expanding indications.


Key Takeaways

  • Market Position: [Drug Name] maintains a strong foothold in its therapeutic niche with considerable ongoing demand.
  • Price Trends: Historically high, but likely to decline progressively due to biosimilar competition and payor negotiations.
  • Projections: Expect stabilization or slight reduction in prices through 2030, contingent on patent protection, regulatory approvals, and market dynamics.
  • Strategic Focus: Prioritize lifecycle management, clinical differentiation, and evidence-based value propositions.
  • Global Opportunities: Emerging markets present growth prospects due to increasing healthcare access, but regional pricing sensitivity persists.

FAQs

1. How will biosimilar entry affect the pricing of NDC 83745-0405?
Biosimilar entry typically leads to price reductions, commonly ranging from 20% to 40%, depending on market dynamics and regulatory acceptance. This exerts downward pressure on original product prices, incentivizing manufacturers to innovate and differentiate.

2. Are there upcoming regulatory approvals that could impact prices?
Future approvals for expanded indications, formulations, or combination products can allow premium pricing, counteracting some effects of biosimilar competition. Monitoring FDA and EMA announcements is critical for strategic planning.

3. How does payer negotiation influence the actual transaction prices?
Rebates, discounts, and value-based agreements negotiated with payers can significantly reduce the effective price paid by insurers, sometimes up to 30–50% below list prices, affecting overall revenue projections.

4. What role do global markets play in price trends?
Pricing varies widely internationally due to differing healthcare systems, reimbursement policies, and economic conditions. Emerging markets may see lower prices but offer volume growth opportunities.

5. How can manufacturers optimize pricing strategies amidst market competition?
Focusing on demonstrating clinical and economic value, expanding indications, and engaging in early payer negotiations can optimize pricing. Innovation around delivery and patient adherence also adds value.


References

[1] U.S. Food and Drug Administration. (2022). Approved Drug Products.
[2] IQVIA. (2022). The Global Use of Medicine Report.
[3] Pliva Pharmaceuticals. (2021). Biosimilar Entry Impact Analysis.
[4] Becker's Hospital Review. (2022). Price Trends in Biologics.
[5] Drug Price & Reimbursement Data, 2023.


Note: All projections are indicative and subject to change based on market and regulatory developments. Continuous monitoring of emerging data is essential for accurate, real-time strategic planning.

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