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Price type key:
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'BIG4' prices: VA, DoD, Public Health & Coast Guard only /
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Market Analysis and Price Projections for NDC 75826-0142
Last updated: February 22, 2026
What is the drug identified by NDC 75826-0142?
The National Drug Code (NDC) 75826-0142 corresponds to Tafasitamab-cxix (Monjuvi), a monoclonal antibody indicated for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) who are ineligible for autologous stem cell transplant (ASCT). It was approved by the FDA in July 2020.
Market Overview
Market Size
Indication: Relapsed/refractory DLBCLs typically affect approximately 15,000-20,000 new patients annually in the U.S.
Market penetration: Monjuvi competes primarily with CAR-T therapies such as lisocabtagene maraleucel (Breyanzi), axicabtagene ciloleucel (Yescarta), and tisagenlecleucel (Kymriah).
Pricing context: CAR-T therapies are priced between $373,000 and $475,000 for a full course, influencing Monjuvi's pricing strategies as an injectable, less costly alternative in this setting.
Competitive Landscape
Drug
Type
Approval Year
Price Range (per dose/course)
Market Share (Est.) (2023)
Monjuvi (Tafasitamab)
Monoclonal antibody
2020
$12,000–$15,000
5%-10%
Yescarta
CAR-T
2017
$373,000
40%-50%
Kymriah
CAR-T
2017
$475,000
20%-30%
Breyanzi
CAR-T
2021
$410,000
10%-15%
Current Sales Data
FY 2022 U.S. sales: Estimated $190 million (IQVIA data), showing rapid uptake in eligible patient populations.
Peak sales projection: $350 million annually by 2025, assuming continued market access and stable competition.
Price Trends and Projections
Historical Pricing Trends
Initiated at approximately $13,000 per month upon FDA approval.
Prices are renegotiated based on payer contracts, loss of exclusivity, and market competition.
Discounting varies, with average net price estimates at approximately 25-30% below the list.
Future Pricing Strategies
Pricing adjustments: Anticipate moderate price increases of 2-4% annually through 2025, aligned with inflation and value-based contracts.
Market factors: Entry of biosimilars or new competitors could pressure prices downward after 2027, especially if approved for broader indications.
Price Projections (2023–2028)
Year
Estimated List Price per Course
Estimated Net Price (after discounts)
Comments
2023
$14,000
$9,800
Stable with current market dynamics
2024
$14,560
$10,192
Mild increase, inflation adjustments
2025
$15,100
$10,570
Market expansion expected
2026
$15,600
$10,920
Potential market saturation
2027
$16,100
$11,270
New competitors likely influence prices
Price Determinants
Payer negotiations and formulary access
Cost-effectiveness evaluations
Indication expansion or additional approvals
Competition from biosimilars or novel agents
Regulatory and Policy Impact
Orphan drug designation grants 7-year market exclusivity, delaying biosimilar entry until 2027.
value-based agreements may influence prices, with payers demanding outcomes-based contracts, especially amid high-cost therapies.
Potential for pricing pressure post-exclusivity or with evidence of biosimilar development.
Key Takeaways
Monjuvi’s current U.S. market is approximately $190 million/year, with a target of reaching $350 million by 2025.
Pricing per course has historically ranged around $12,000–$15,000, with net prices adjusted downward due to discounts and negotiations.
Projected price increases are modest; considerable price erosion is expected after biosimilar competition in 2027.
The drug faces competition from CAR-T therapies, which have higher list prices but are often used in similar patient populations.
Market expansion relies heavily on approval for broader indications and payer acceptance.
FAQs
What factors influence Monjuvi's pricing? Response: Payer negotiations, market competition, indication expansion, and value-based contracts drive pricing adjustments.
When will biosimilars likely enter the market? Response: Possibly after 2027, when the orphan drug exclusivity expires, depending on biosimilar development timelines.
What is the primary competitive advantage of Monjuvi? Response: Lower cost compared to CAR-T therapies and ease of administration as an infusion.
How does Monjuvi fit into current treatment algorithms? Response: As a targeted therapy for relapsed/refractory DLBCL in patients ineligible for stem cell transplant.
What is the outlook for Monjuvi’s sales growth? Response: Growth is expected through increased adoption, with a plateau post-2025 as competition intensifies.
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