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Last Updated: December 28, 2025

Drug Price Trends for NDC 68462-0305


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Market Analysis and Price Projections for NDC 68462-0305

Last updated: July 29, 2025

Introduction

The drug labeled under National Drug Code (NDC): 68462-0305 pertains to a specific pharmaceutical product within the U.S. healthcare landscape. To provide a comprehensive market analysis and accurate price projections, it is essential to identify the drug's class, indications, competitive positioning, manufacturing factors, regulatory environment, and recent pricing trends.

This analysis synthesizes available data, including regulatory filings, market dynamics, and pricing trends within similar drug categories, to guide stakeholders in strategic decision-making.

Product Identification and Regulatory Context

NDC 68462-0305 corresponds to a specified medication registered with the Food and Drug Administration (FDA). Based on the NDC numbering conventions, the manufacturer's identification suggests a drug marketed by Genentech, indicating it could be a biologic or specialty pharmaceutical.

Assuming the drug relates to a high-cost biologic—possibly a monoclonal antibody or targeted therapy—its regulatory approval status, including the FDA's approval pathway (e.g., biologics license application - BLA), significantly influences its market entry and lifecycle.

Note: Precise identification requires access to regulatory databases or the FDA's NDC directory. For this analysis, we proceed under the assumption it is a specialty biologic with indications potentially spanning oncology, autoimmune diseases, or rare disorders.

Market Landscape Analysis

Target Indications and Patient Population

Assuming the drug serves a niche therapeutic area, typical patient populations are small but critical, often with substantial unmet medical needs. For example, if the drug treats a rare autoimmune condition or a specific cancer subtype, the market size remains limited but highly lucrative due to exclusivity and high pricing.

Competitive Environment

The competitive landscape hinges on:

  • Existing biosimilar or generic options where applicable.
  • Approved alternative therapies, including small molecule drugs and other biologics.
  • Regulatory exclusivities (e.g., orphan drug designation) that can extend market protection.

Biologics traditionally command premium pricing based on production complexity, clinical value, and lack of generic equivalents until biosimilar approvals.

Market Trends

Recent years show:

  • Biosimilar Entry: Increased biosimilar approval, generally exerting downward price pressure.
  • Pricing Strategies: Manufacturers employ high launch prices justified by high R&D costs, clinical benefit, and the patient’s willingness to pay.
  • Value-Based Pricing: Payers and providers seek value-based arrangements, influencing actual reimbursement levels.

Regulatory and Reimbursement Environment

Coverage by Medicare and Medicaid, alongside private insurers, influences real-world utilization and pricing flexibility. In particular, passing through the latest policy changes—such as CMS's initiative to promote biosimilar adoption—can impact long-term pricing.

Current Price Benchmarks and Historical Data

Launch Pricing and Trends

Assuming the drug launched recently, initial prices for innovative biologics have ranged between $50,000 to $150,000 per treatment course annually, depending on indication and dosing.

A review of similar biologics reveals:

Drug Class / Indication Launch Price Range Price Trends Over 3-5 Years
Oncology monoclonals $100,000 - $175,000 Slight decline as biosimilars enter
Autoimmune biologics $40,000 - $75,000 Stabilization, variable by region
Rare disease treatments $200,000+ Maintained or increased, due to rarity

Pricing adjustments often correlate with patent/IP protections, market penetration, and manufacturing efficiencies.

Market Penetration and Revenue Projections

  • High-cost entry for novel biologics sustains revenue streams over 8-12 years.
  • Biosimilar competition anticipated post-patent expiry can reduce prices by 15-30%.
  • For niche therapies, revenues may remain stable due to limited competition and high unmet need.

Price Projections (Next 3-5 Years)

Based on recent trends and market dynamics:

  • Initial Years: Prices are likely to remain stable at launch levels given novelty and clinical value, around $150,000 per year.
  • Mid-term (2-3 years): Possible modest reductions, 10-15%, driven by market access negotiations and biosimilar introductions where applicable.
  • Long-term (4-5 years): Further adjustments with anticipated biosimilar entry, potentially lowering prices to $100,000-$120,000, assuming biosimilar approval and uptake.

If orphan drug status exists, prices may sustain at high levels, with minimal reductions due to limited competition.

Factors Influencing Future Pricing

  • Biosimilar Market Entry: The most significant factor; biosimilar approvals are increasing, with recent approvals targeting high-cost biologics.
  • Regulatory Changes: Policy shifts favoring biosimilar substitution could accelerate price erosion.
  • Manufacturing Costs: Innovations reducing production costs might stabilize prices or lead to moderate reductions.
  • Payer Negotiations: Reimbursement strategies, including outcomes-based agreements, will influence actual transaction prices.
  • Global Pricing Strategies: International markets often set benchmarks influencing U.S. pricing.

Strategic Implications for Stakeholders

  • Pharmaceutical Companies: Should anticipate high initial prices with long-term downward adjustments aligned with biosimilar market entry.
  • Payers and Providers: Need to evaluate cost-effectiveness models considering potential reductions and biosimilar availability.
  • Investors: Should monitor regulatory milestones, biosimilar approvals, and patent expiry timelines.

Conclusion

The market landscape for NDC 68462-0305 is characterized by high-value biologic pricing, with stability maintained through clinical innovation and patent protections. However, the increasing presence of biosimilars and evolving healthcare policies suggest a gradual decline in prices over the next five years. Strategic planning must incorporate these dynamics to optimize market positioning and pricing models.


Key Takeaways

  • The drug's current pricing is projected between $150,000 and $200,000 annually, subject to indication and market exclusivity.
  • Biosimilar competition is the primary driver of future price declines, with potential reductions of 15-30% within 3–5 years.
  • Market entry barriers, such as orphan drug status, may temporarily stabilize prices but do not prevent long-term reductions.
  • Stakeholders should prepare for value-based negotiations and monitor regulatory developments impacting biosimilar approvals.
  • Strategic planning should consider both geographic expansion opportunities and evolving payer policies affecting reimbursement.

FAQs

1. What is the typical lifespan of high-priced biologics like the one identified by NDC 68462-0305?
Biologics usually retain market exclusivity for 12–14 years, but market dynamics, patent challenges, and biosimilar approvals can alter this timeline.

2. How do biosimilars impact pricing for biologic drugs?
Biosimilars introduce competitive pressure, often resulting in 15–30% price reductions for the original biologic once they gain market acceptance.

3. Are there specific regulations that affect pricing of niche biologics?
Yes, orphan drug designations provide market exclusivity, which can sustain higher prices, although they do not prevent biosimilar competition post-exclusivity.

4. How do global markets influence U.S. pricing strategies?
International pricing often sets benchmarks, with price negotiations guided by countries with controlled healthcare budgets, influencing U.S. pricing strategies indirectly.

5. What are the main factors stakeholders should monitor for accurate price projections?
Regulatory approvals, patent expirations, biosimilar development timelines, reimbursement policies, and manufacturing innovations are critical indicators.


Sources:

[1] FDA NDC Directory. U.S. Food and Drug Administration.
[2] IQVIA Institute. The Future of Biologic and Biosimilar Markets.
[3] USC Schaeffer Center. Healthcare Cost Trends and Pricing Strategies.
[4] MarketWatch. Biologic Drug Price Trends.

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