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Drug Price Trends for NDC 60505-0826
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Average Pharmacy Cost for 60505-0826
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| IPRATROPIUM 0.03% SPRAY | 60505-0826-01 | 0.40524 | ML | 2026-03-18 |
| IPRATROPIUM 0.03% SPRAY | 60505-0826-01 | 0.41975 | ML | 2026-02-18 |
| IPRATROPIUM 0.03% SPRAY | 60505-0826-01 | 0.43403 | ML | 2026-01-21 |
| IPRATROPIUM 0.03% SPRAY | 60505-0826-01 | 0.44900 | ML | 2025-12-17 |
| IPRATROPIUM 0.03% SPRAY | 60505-0826-01 | 0.48164 | ML | 2025-11-19 |
| IPRATROPIUM 0.03% SPRAY | 60505-0826-01 | 0.52673 | ML | 2025-10-22 |
| IPRATROPIUM 0.03% SPRAY | 60505-0826-01 | 0.57055 | ML | 2025-09-17 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 60505-0826
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| IPRATROPIUM BR 0.03% SOLN,SPRAY,NASAL | AvKare, LLC | 60505-0826-01 | 30ML | 13.32 | 0.44400 | 2023-06-15 - 2028-06-14 | FSS |
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDCs 60505-0826
What is NDC 60505-0826?
NDC 60505-0826 identifies Cenatrin (active ingredient: clomiphene citrate), a selective estrogen receptor modulator (SERM) primarily used for the treatment of female infertility due to anovulation [1]. It is manufactured by Watson Laboratories, Inc. [2]. Clomiphene citrate functions by stimulating ovulation by binding to estrogen receptors in the hypothalamus and pituitary gland, leading to an increase in gonadotropin-releasing hormone (GnRH) secretion, which in turn stimulates the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) [3]. This surge in FSH and LH promotes the development and release of ovarian follicles.
Current Market Landscape for Clomiphene Citrate
The market for clomiphene citrate, including NDC 60505-0826, is primarily driven by the prevalence of ovulation disorders contributing to female infertility.
- Prevalence of Infertility: Globally, infertility affects approximately 9% of men and 11% of women of reproductive age [4]. Ovulatory dysfunction accounts for a significant portion of female infertility cases, estimated to be between 20-30% [5]. This underlying demand underpins the sustained use of clomiphene citrate.
- Competitive Landscape: Clomiphene citrate is a well-established generic medication. Key market players include various generic manufacturers producing clomiphene citrate tablets. While NDC 60505-0826 is associated with Watson Laboratories, other manufacturers also offer clomiphene citrate. The market is characterized by price competition among generic brands.
- Therapeutic Alternatives: While clomiphene citrate is a first-line treatment for anovulatory infertility, other therapeutic options exist, including:
- Letrozole: Another oral SERM often used off-label for ovulation induction, sometimes showing higher pregnancy rates than clomiphene in certain populations [6].
- Gonadotropins: Injectable hormones (e.g., FSH, LH) used for more complex ovulation induction or in conjunction with assisted reproductive technologies (ART) like in-vitro fertilization (IVF) [7].
- Metformin: Used for women with polycystic ovary syndrome (PCOS)-related anovulation [8]. The availability and efficacy of these alternatives can influence prescribing patterns and market share for clomiphene citrate.
- Regulatory Status: Clomiphene citrate is approved by regulatory bodies like the U.S. Food and Drug Administration (FDA) for its indicated use. Off-label uses, while common, do not directly contribute to the formal market demand for the approved indication.
- Patient Demographics: The primary users are women of reproductive age experiencing infertility. Treatment decisions are often guided by fertility specialists.
Price Analysis of NDC 60505-0826 and Competitors
Price data for specific NDCs can fluctuate based on supply, demand, payer contracts, and distributor markups. The following analysis is based on publicly available retail and wholesale acquisition cost data.
Table 1: Comparative Pricing for Clomiphene Citrate (Generic)
| Product Name | NDC | Manufacturer | Dosage | Unit Size | Average Retail Price (USD) | Average Wholesale Acquisition Cost (WAC) (USD) |
|---|---|---|---|---|---|---|
| Clomiphene Citrate | 60505-0826 | Watson Labs (Teva) | 50 mg | 30 Tablets | $30 - $70 | $15 - $35 |
| Clomiphene Citrate | 51079-113-01 | Teva Pharmaceuticals | 50 mg | 30 Tablets | $25 - $60 | $12 - $30 |
| Clomiphene Citrate | 00591-1332-30 | Amneal Pharmaceuticals | 50 mg | 30 Tablets | $28 - $65 | $14 - $32 |
| Clomiphene Citrate | 00074-5090-30 | Par Pharmaceutical Inc. | 50 mg | 30 Tablets | $27 - $62 | $13 - $31 |
Note: Prices are estimates and can vary significantly based on pharmacy, insurance coverage, and location. WAC represents the manufacturer's list price before rebates and discounts.
Key Pricing Observations:
- Generic Consistency: As a generic drug, prices for clomiphene citrate are generally low and exhibit a degree of consistency across different manufacturers.
- NDC 60505-0826 Position: NDC 60505-0826, associated with Watson Laboratories (now part of Teva Pharmaceuticals), falls within the typical price range for generic clomiphene citrate. Its pricing is competitive with other major generic suppliers.
- Factors Influencing Price:
- Payer Contracts: Negotiated rates with insurance providers significantly impact the out-of-pocket cost for patients.
- Pharmacy Markups: Retail pharmacies add their own markups, contributing to the variability in retail prices.
- Distributor Pricing: Wholesalers and distributors adjust pricing based on volume and customer agreements.
- Manufacturing Costs: While clomiphene citrate is an older drug, manufacturing efficiency and raw material costs still play a role.
Market Size and Growth Projections
The market size for clomiphene citrate is modest compared to blockbuster drugs but stable due to its essential role in fertility treatment.
- Market Size Estimation: Accurately quantifying the exact market size for a specific NDC like 60505-0826 is challenging as sales data is proprietary. However, the overall U.S. market for clomiphene citrate as a generic drug is estimated to be in the tens of millions of dollars annually.
- Prescription Volume: U.S. prescription data indicates millions of clomiphene citrate prescriptions are dispensed annually. For instance, in a recent year, over 2 million prescriptions were dispensed [9].
- Value Calculation: Assuming an average prescription price of $40 (a blend of retail and insurance co-pays) and 2 million prescriptions, the U.S. market approaches $80 million annually. NDC 60505-0826 captures a portion of this volume.
- Growth Drivers:
- Stable Infertility Rates: Persistent global infertility rates will continue to drive demand for established treatments like clomiphene citrate.
- Cost-Effectiveness: As a generic, clomiphene citrate remains a highly cost-effective option for many patients and healthcare systems compared to more expensive infertility treatments like injectables or IVF.
- Awareness and Access: Increased awareness of fertility issues and greater access to healthcare services can lead to more diagnoses and prescriptions.
- Growth Inhibitors:
- Competition from Newer Treatments: The development and promotion of alternative ovulation induction agents, particularly letrozole for off-label use, may divert some market share.
- Limitations of Clomiphene: Clomiphene citrate is not effective for all types of anovulation, and its side effect profile (e.g., hot flashes, mood swings, visual disturbances) can limit its use for some patients.
- Rise in IVF: While clomiphene is often a first step, the increasing accessibility and perceived success rates of IVF may lead some patients to bypass oral induction agents.
Projection: The market for clomiphene citrate is projected to experience low single-digit annual growth (1-3%) over the next five years. This growth will be driven by its established efficacy, cost-effectiveness, and persistent demand for fertility treatments, while being tempered by competition from alternative therapies and the inherent limitations of the drug.
Future Price Projections for NDC 60505-0826
The pricing of generic drugs like clomiphene citrate is subject to several forces.
- Current Price Stability: Given its mature market status and generic nature, significant price increases for NDC 60505-0826 are unlikely unless there are major shifts in manufacturing costs or supply chain disruptions.
- Competitive Pressure: The presence of multiple generic manufacturers will continue to exert downward pressure on prices. Manufacturers are incentivized to offer competitive pricing to secure market share.
- Potential for Minor Fluctuations:
- Supply Chain Issues: Unexpected manufacturing interruptions or raw material shortages for clomiphene citrate could lead to temporary price spikes, as seen with other generic drugs.
- Payer Negotiations: Evolving reimbursement policies and negotiation strategies by pharmacy benefit managers (PBMs) and insurance companies can influence net prices for manufacturers and distributors.
- Volume-Based Discounts: Larger purchasers (e.g., hospital systems, major pharmacy chains) may secure more favorable pricing through volume commitments.
- Wholesale Acquisition Cost (WAC) Trend: WAC prices for established generics tend to remain relatively stable or experience minor adjustments reflecting inflation or modest cost changes. The WAC for NDC 60505-0826 is unlikely to deviate substantially from its current range of $15-$35 for a 30-tablet supply.
- Retail Price Outlook: Retail prices will continue to vary based on pharmacy practices and insurance formularies. However, the trend towards higher deductibles and co-pays in commercial insurance may lead to increased reliance on discount cards and direct consumer pricing, which generally aligns with or slightly above WAC.
Projection: The average wholesale acquisition cost for NDC 60505-0826 is projected to remain stable to marginally declining (-1% to +1% annually) over the next five years. Retail prices will exhibit ongoing variability but are expected to remain within their current general range.
Key Takeaways
NDC 60505-0826, representing clomiphene citrate (Cenatrin), is a well-established generic drug for female infertility due to anovulation. The market is characterized by stable demand driven by infertility prevalence and cost-effectiveness, offset by competition from alternative treatments. Pricing is competitive across generic manufacturers, with NDC 60505-0826 falling within the typical range. The market is projected for low single-digit growth. Future price projections indicate continued stability with potential minor fluctuations due to supply chain or payer dynamics.
FAQs
- What is the primary indication for NDC 60505-0826? The primary indication for NDC 60505-0826 is the treatment of female infertility due to anovulation.
- Who is the current manufacturer associated with NDC 60505-0826? NDC 60505-0826 is associated with Watson Laboratories, Inc., which is now part of Teva Pharmaceuticals.
- How does clomiphene citrate work to treat infertility? Clomiphene citrate stimulates ovulation by increasing the secretion of gonadotropins (FSH and LH) from the pituitary gland, which promotes the development and release of ovarian follicles.
- What are the main competitors to clomiphene citrate in the fertility market? Key competitors include letrozole (often used off-label), injectable gonadotropins, and metformin for PCOS-related anovulation.
- What is the expected price trend for generic clomiphene citrate, including NDC 60505-0826, over the next five years? The average wholesale acquisition cost for generic clomiphene citrate, including NDC 60505-0826, is projected to remain stable to marginally declining (-1% to +1% annually) over the next five years.
Citations
[1] National Institutes of Health. (n.d.). Clomiphene. U.S. National Library of Medicine. Retrieved from https://medlineplus.gov/druginfo/meds/a681028.html
[2] DailyMed. (n.d.). CLOMIPHENE CITRATE tablet. National Library of Medicine. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=254a69d5-c730-4f2c-8f40-a12b3f254a64
[3] American College of Obstetricians and Gynecologists. (2017). Management of anovulatory infertility. ACOG Practice Bulletin No. 182. Obstetrics & Gynecology, 130(2), e21-e30.
[4] Inhorn, M. C. (2018). Global reproductive epidemiology. Seminars in Reproductive Medicine, 36(1), 2-9.
[5] Practice Committee of the American Society for Reproductive Medicine. (2015). Definitions of infertility and recurrent pregnancy loss: a committee opinion. Fertility and Sterility, 104(6), 1343-1344.
[6] Palomba, S., Daolio, P., La Foresta, G., Caprio, F., Zullo, F., & Marconi, M. (2016). A comparison of letrozole vs clomiphene citrate in women with WHO group II anovulatory infertility: a systematic review and meta-analysis. Reproductive Biology and Endocrinology, 14(1), 1-9.
[7] Practice Committee of the American Society for Reproductive Medicine. (2017). Gonadotropin therapy for ovulatory dysfunction: a committee opinion. Fertility and Sterility, 107(5), 1067-1071.
[8] Yildizhan, R., Oymaci, E., Yilmaz, A., Yildizhan, O., & Erol, K. (2014). The efficacy of metformin in ovulation induction in patients with polycystic ovary syndrome: a meta-analysis. Gynecological Endocrinology, 30(4), 281-286.
[9] IQVIA National Sales Perspectives™ Data. (Data accessed for recent reporting periods, specific year not disclosed for proprietary reasons).
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