These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Price type key:
Federal Supply Schedule (FSS): generally available to all Federal Govt agencies /
'BIG4' prices: VA, DoD, Public Health & Coast Guard only /
National Contracts (NC): Available to specific agencies
Market Analysis and Price Projections for NDC 55111-0519
Last updated: February 25, 2026
What is the drug identified by NDC 55111-0519?
The National Drug Code (NDC) 55111-0519 corresponds to Eliquis (apixaban), an anticoagulant used primarily for stroke prevention in atrial fibrillation, treatment of deep vein thrombosis (DVT), pulmonary embolism (PE), and reduction of thrombotic events post-hip or knee replacement.
Market Size and Adoption Trends
Current Market Overview
The global anticoagulant market was valued at approximately $10 billion in 2022.
Eliquis holds a leading position in the direct oral anticoagulant (DOAC) segment, with a market share exceeding 60% in the U.S.
Market Drivers
Increasing incidence of atrial fibrillation (AFib) and venous thromboembolism (VTE).
Growing preference for DOACs over warfarin due to favorable safety and convenience profiles.
Expanding indications, including prophylaxis in orthopedic surgeries and hospitalized patients.
Competitive Landscape
Player
Market Share (2022)
Key Products
Notable Features
Pfizer/Bristol-Myers
>60%
Eliquis
Established brand, broad indication coverage
Bayer
Around 20%
Xarelto
Strong global presence
Boehringer Ingelheim
~10%
Pradaxa
First-in-class oral anticoagulant
Others
<10%
Various generics
Emerging generic competition
Market Growth Expectations
Compound annual growth rate (CAGR) projected at 8-10% from 2023-2028, driven by increased indications and aging populations.
Price Trends and Projections
Current Pricing Dynamics
In the U.S., the average wholesale price (AWP) for a 60-dose pack of Eliquis ranges between $400-$500.
Insurance reimbursement, discounts, and pharmacy benefit manager (PBM) negotiations significantly influence actual patient costs.
Factors Affecting Price Trajectory
Patent exclusivity and looming patent expiry deadlines.
Entry of generics or biosimilars.
Market penetration in emerging economies.
Changes in clinical guidelines and formulary placements.
Patent and Regulatory Timeline
Patent expiration originally scheduled for around 2026. (Eliquis received a U.S. patent extension until 2029.)
Potential generic entry may lead to price reductions of 50% or more.
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