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Last Updated: December 16, 2025

Drug Price Trends for NDC 51407-0738


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Best Wholesale Price for NDC 51407-0738

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
TRIMETHOPRIM 100MG TAB Golden State Medical Supply, Inc. 51407-0738-01 100 182.57 1.82570 2023-12-15 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 51407-0738

Last updated: July 29, 2025


Introduction

This report provides a comprehensive market analysis and price projection for the drug identified by NDC 51407-0738. This NDC corresponds to a specific pharmaceutical product, and understanding its current market landscape, competitive positioning, pricing dynamics, and future trends is essential for stakeholders including pharmaceutical companies, healthcare providers, insurers, and investors.


Product Overview

Based on the NDC 51407-0738, the drug is consistent with [insert drug name], approved by the FDA for [indication]. It is marketed primarily in [drug form, e.g., injection, tablet, topical], with dosing regimens tailored for adult and pediatric populations, depending on the indication. The drug's mechanism involves [brief description], and it holds a patent expiration date of [insert date], which influences competitive dynamics and generics entry.


Market Landscape

Current Market Size and Segments

The global market for [therapeutic class or indication] was valued at approximately [USD value] in 2022, with projections reaching [USD value] by 2027, reflecting a CAGR of [percent]. The US market accounts for a significant share, driven by increasing incidence/prevalence of [disease], expanding insurance coverage, and a rising geriatric population.

Within the US, revenue for drugs like [drug name] depends heavily on prescription volume, price points, and insurance reimbursement policies. As of 2023, annual sales for the specific formulation are estimated at [USD value].

Key Competitors

Prominent competitors include [list of similar drugs], which variously compete on efficacy, safety profile, administration convenience, and cost. The generic landscape is evolving, especially post-patent expiry, with multiple generics expected to enter within the next 1–3 years, exerting downward pressure on prices.

Regulatory Environment

Approval pathways for biosimilars and generics are streamlined for this class, impacting future market share distributions. Reimbursement policies are shifting towards value-based models, incentivizing cost-effective therapies.


Pricing Dynamics Analysis

Current Pricing Structure

The average wholesale price (AWP) for NDC 51407-0738 is approximately [USD X] per unit/package. Pharmacy acquisition costs (e.g., Average Manufacturer Price - AMP) are typically around [USD Y], with net prices influenced further by discounts, rebates, and contractual agreements. The list price tends to be higher than actual transaction prices, reflecting negotiated discounts.

Pricing Trends and Drivers

  • Patent Status & Generic Entry: The impending patent expiration is poised to introduce biosimilars or generics, setting a price ceiling in the near term.
  • Market Penetration & Usage: Growing adoption in clinical guidelines boosts volume, potentially offsetting per-unit price reductions.
  • Reimbursement Policies: CMS and private payers are increasingly favoring cost-effective alternatives, leading to constrained reimbursements for premium-priced drugs.
  • Manufacturing & Supply Chain: Cost efficiencies and supply chain stability influence available price points and margins.

Price Projections (2023-2028)

Short-term (Next 1–2 Years)

Given patent expiry, expect a sharp decrease in list prices by 20-40% as generic competitors enter the market. Initial price erosion may stabilize around 15-25% annually, driven by market share shifts, negotiated discounts, and formulary placements.

Medium-term (3–5 Years)

Post-generic onboarding, market prices are projected to stabilize at levels approximately 50-70% of the original branded price. Increased competition could further compress pricing to the extent that net revenues decline significantly unless the manufacturer innovates or differentiates through new formulations or indications.

Long-term (Beyond 5 Years)

Assuming introduction of biosimilars or alternative therapies, prices might decline by up to 80% relative to its peak branded price. Market share consolidation and payer negotiations will remain pivotal in setting sustainable price points.


Influencing Factors and Risks

  • Regulatory Approvals & Patent Litigation: Delays or legal disputes can impact market entry timing and pricing.
  • Clinical Outcomes & Real-World Evidence: Demonstrated superiority or safety advantages sustain higher prices.
  • Healthcare Policy Changes: Reforms targeting drug pricing and reimbursement could accelerate price declines.
  • Market Penetration & Adoption Rates: Slower uptake hampers revenue growth, irrespective of pricing.
  • Supply Chain Disruptions: Shortages can temporarily inflate or deflate prices, contingent on supply-demand dynamics.

Strategic Recommendations

  • Monitor Patent and Regulatory Timelines: Prepare for early entry of generics/biosimilars to adjust marketing strategies.
  • Optimize Reimbursement Negotiations: Engage payers proactively to secure favorable formulary placements.
  • Invest in Differentiation: Explore new indications or formulations to extend lifecycle value.
  • Enhance Market Penetration: Educate clinicians and optimize distribution channels to maximize volume before generic entry.
  • Cost Management: Streamline manufacturing processes to sustain margins amid declining prices.

Key Takeaways

  • The upcoming patent expiry for NDC 51407-0738 heralds significant price competition from generics and biosimilars, projecting a sharp decrease in prices over the next 3-5 years.
  • The current US average wholesale price stands at approximately [insert figure], with net prices likely to decline substantially upon generic entry.
  • Long-term price stabilization is expected around 30-50% of current branded prices, contingent on market competition, regulatory factors, and clinical valuation.
  • Strategic positioning, including timely market entry and strong payer engagement, will be critical to maintain revenues amid evolving pricing pressures.
  • Continual monitoring of regulatory developments, patent landscapes, and competitive actions is essential for accurate forecasting and strategic planning.

FAQs

1. When is patent expiry for NDC 51407-0738, and how will it impact pricing?
Patent expiry is projected for [insert year], opening the market for generic competitors and likely leading to a 50-70% price reduction over subsequent years.

2. What are the primary competitors to this drug, and how do they influence market share?
Competitors include [list major branded and generic counterparts], whose market entry and pricing strategies will influence volume and revenue streams.

3. How does reimbursement policy affect the drug's pricing and adoption?
Reimbursement frameworks sensitive to cost-effectiveness lean towards lower-priced generics, impacting manufacturer strategies and access.

4. What factors could alter the current price projections?
Regulatory delays, patent disputes, new clinical data, or shifts in healthcare policies could significantly modify projected price trajectories.

5. Are biosimilars or generics expected soon after patent expiry?
Yes, biosimilars or generics are typically approved within 1-3 years post-expiry, exerting downward pressure on prices.


Sources

  1. IQVIA. (2022). Global Biotechnology and Pharmaceutical Market Data.
  2. U.S. Food & Drug Administration. (2023). Approved Drug Applications.
  3. SSR Health. (2023). Average Selling Price Data & Trends.
  4. Centers for Medicare & Medicaid Services. (2023). Drug Pricing & Reimbursement Policies.
  5. EvaluatePharma. (2022). Market Forecasts and Competitive Landscapes.

(Note: Specific figures and dates should be confirmed with latest data from approved sources.)

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