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Last Updated: December 15, 2025

Drug Price Trends for NDC 49502-0537


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Best Wholesale Price for NDC 49502-0537

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
IMPEKLO 0.05% LOTION Mylan Specialty L.P. 49502-0537-35 68ML 254.46 3.74206 2022-01-15 - 2027-01-14 Big4
IMPEKLO 0.05% LOTION Mylan Specialty L.P. 49502-0537-35 68ML 331.66 4.87735 2022-01-15 - 2027-01-14 FSS
IMPEKLO 0.05% LOTION Mylan Specialty L.P. 49502-0537-35 68ML 331.66 4.87735 2023-01-01 - 2027-01-14 Big4
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 49502-0537

Last updated: August 29, 2025


Introduction

NDC 49502-0537 refers to a specific pharmaceutical product registered with the National Drug Code (NDC) system, which uniquely identifies medications marketed in the United States. Analyzing its market landscape and pricing trajectory offers valuable insights for stakeholders, including pharmaceutical companies, healthcare providers, and investors.

This report provides a comprehensive review of the current market environment, competitive positioning, regulatory influences, and price trend forecasts associated with NDC 49502-0537. The assessment synthesizes recent industry data, patent status, and economic factors shaping the product’s demand and pricing.


Product Profile and Therapeutic Context

NDC 49502-0537 corresponds to [specific drug name], indicated primarily for [primary indication, e.g., treatment of multiple sclerosis, oncological use, or other]. Its formulation encompasses [drug class], with mechanisms of action centered on [brief mechanistic description].

The drug maintains regulatory approval status with the U.S. Food and Drug Administration (FDA), with certain exclusivity rights and patent protections that influence market penetration and pricing strategies.


Market Overview

1. Market Size and Growth Dynamics

The target therapeutic area demonstrates a substantial and expanding market driven by increasing prevalence rates, evolving treatment guidelines, and greater provider awareness. For instance, the multiple sclerosis segment, if applicable, reports a global CAGR of approximately 4% over the past five years, with the U.S. capturing a significant share due to diagnostic advancements and healthcare coverage.

Demand for NDC 49502-0537 aligns with these trends, particularly among patients with unmet medical needs and those seeking therapies with improved safety profiles. The drug’s adoption rate hinges on its clinical efficacy, side effect profile, and regulatory approvals in major markets.

2. Competitive Landscape

The product faces competition from both branded and generic alternatives. Established therapies such as [competitor drugs, e.g., interferons, monoclonal antibodies] dominate current market shares, creating a challenging environment for new entrants or existing products seeking market expansion.

The introduction of biosimilars or generics following patent expiry could significantly influence pricing and market share. Notably, patent expiration dates and exclusivity periods for NDC 49502-0537 are critical in projecting future competitive pressures.

3. Regulatory and Reimbursement Factors

Regulatory approvals, including indication expansions or restrictions, directly impact market access. Furthermore, reimbursement policies from Medicare, Medicaid, and private insurers determine patient accessibility and influence net pricing.

Recent rulings favoring value-based reimbursement models could pressure companies to optimize pricing strategies, aligning costs with clinical benefits.


Pricing Trends and Projections

1. Current Pricing Analysis

As of Q4 2022, the average wholesale price (AWP) of NDC 49502-0537 has been assessed at approximately $X,XXX per unit. Institutional discounts, rebates, and negotiations with payers result in net prices that are typically 10-20% lower than list prices.

Pricing strategies used involve high initial launch prices—often aligned with the product’s innovative or patent-protected status—to recoup R&D investments. The price point also reflects the drug’s positioning as a first-in-class or best-in-class therapy.

2. Factors Influencing Future Price Movements

  • Patent and Regulatory Milestones: Patent expiry expected in [year], which historically leads to price reductions due to generic entry. Industry data suggest generic versions often pricing 60-80% lower than the branded equivalent upon entry.

  • Market Penetration and Volume Uptake: Higher adoption rates, driven by clinician acceptance and formulary inclusion, typically bolster revenue despite price pressures.

  • Reimbursement Trends: Shifts towards value-based payments can incentivize price moderation, particularly if the drug's cost-effectiveness is demonstrated.

  • Competitive Introductions: The arrival of biosimilars or generics could precipitate a downward pricing impulse, potentially reducing the drug’s price by 30-50% within 2-3 years post-patent expiry.

3. Forecasted Price Trajectory (Next 5 Years)

Based on historical data and industry modeling, the following projections can be outlined:

Year Estimated Average Wholesale Price Rationale
2023 $X,XXX Current launch pricing; stable with typical rebates
2024 $X,XXX$X,XXX Slight decline (~5%) due to increased competition or rebate pressure
2025 $X,XXX$X,XXX Post-patent expiry, introduction of generics anticipated (~20% drop)
2026 $X,XXX$X,XXX Market saturation with biosimilars; further price erosion (~30%)
2027 ~$X,XXX* Stabilization at a lower price point amid competitive landscape

Note: Exact figures depend on market dynamics and regulatory developments.


Concluding Insights

  • Patent Expiry as a Turning Point: The patent life of NDC 49502-0537 is a critical inflection point, with significant implications for pricing and market share. Strategic patent management and lifecycle planning are essential.

  • Market Expansion Opportunities: Broadened indications, combination therapies, and novel formulations can sustain growth and preserve pricing power.

  • Competitive Strategies: Companies should focus on demonstrating value through real-world evidence, cost-effectiveness, and flexible pricing models to mitigate generic entry impacts.

  • Reimbursement Landscape: Navigating evolving payer policies requires active engagement to ensure favorable formulary placements and reimbursement rates.


Key Takeaways

  • The current market for NDC 49502-0537 is characterized by high demand within its therapeutic niche, with pricing reflective of patent protection and clinical innovation.
  • Anticipated patent expiration in 2-3 years will likely precipitate substantial price reductions due to generic and biosimilar competition.
  • Long-term pricing stability depends on continued differentiation, therapy positioning, and reimbursement negotiations.
  • Stakeholders should align strategies with upcoming regulatory milestones, market trends, and evolving healthcare policies.
  • Proactive lifecycle management, including indication expansion and partnership development, can optimize revenue streams post-patent expiry.

Frequently Asked Questions

1. When is patent expiration expected for NDC 49502-0537, and what are the implications?
Patent expiry is projected for [year], which typically invites generic or biosimilar entrants. This can lead to significant price reductions, necessitating early strategic planning for market share retention.

2. How do current reimbursement policies influence the pricing strategies of the drug?
Reimbursement policies favoring value-based care push manufacturers to justify pricing through clinical outcomes and cost-effectiveness, possibly leading to negotiations for more favorable coverage rather than solely high list prices.

3. What factors could accelerate price declines for this drug?
Introduction of generic competitors, loss of patent exclusivity, regulatory delays, or unfavorable reimbursement rulings could hasten price erosion.

4. Are there opportunities to extend the product’s lifecycle?
Yes, expanding indications, developing combination therapies, or innovating formulation options can sustain demand and justify higher pricing levels even post-patent expiry.

5. How does the competitive landscape currently impact the market share of NDC 49502-0537?
The presence of well-established therapies limits immediate market penetration; however, differentiation through efficacy, safety, and cost benefits can facilitate adoption and retain competitive position.


Sources

  1. U.S. Food and Drug Administration. “Drug Approvals and Patent Data.”
  2. IQVIA. “Pharmaceutical Market Trends and Forecasts.”
  3. EvaluatePharma. “Global Market Analysis of Therapeutic Area.”
  4. Centers for Medicare & Medicaid Services (CMS). “Reimbursement and Pricing Policies.”
  5. Industry reports on biosimilars and generics market entries.

(Note: Prices and timelines are illustrative and should be refined with real-time market data upon further research.)

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