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Last Updated: December 30, 2025

Drug Price Trends for NDC 49348-0690


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Best Wholesale Price for NDC 49348-0690

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC: 49348-0690

Last updated: August 3, 2025

Introduction

NDC (National Drug Code) 49348-0690 identifies a specific pharmaceutical product whose market landscape is complex and evolving. As a crucial element in the healthcare supply chain, understanding the current market dynamics and future pricing trajectory of this drug is vital for stakeholders including manufacturers, healthcare providers, payers, and investors. This analysis examines the drug’s market positioning, competitive landscape, regulatory environment, and projected pricing trends to inform strategic decision-making.

Product Profile and Therapeutic Area

While detailed specifics for NDC 49348-0690 require direct access to proprietary or FDA databases, the NDC typically indicates a brand or generic medication within a particular therapeutic category. Based on available data (assuming it belongs to a niche such as oncology, neurology, or infectious diseases), drugs in these categories often face high research and development costs, strict regulatory oversight, and dynamic competitive pressures.

If, for instance, ND C49348-0690 is a monoclonal antibody used in oncology, it likely targets a specific receptor or pathway, with commercialization driven by expanding indications and evolving treatment protocols. Alternatively, if in infectious disease, the price may reflect manufacturing complexities and resistance patterns.

Market Landscape

Demand Drivers

Demand for NDC 49348-0690 hinges on multiple factors:

  • Unmet Medical Need: The extent to which this drug addresses a gap in current treatment options influences prescribing volume. For example, treatments for rare or resistant conditions tend to sustain higher prices due to low competition and high unmet needs.
  • Epidemiology: Prevalence and incidence rates of the target condition directly impact sales volume. In a high-prevalence disease, the drug's market penetration will be significant.
  • Treatment Guidelines and Reimbursement Policies: Adoption depends on clinical guidelines, payer reimbursement levels, and formulary placements, all of which shape prescribing patterns.
  • Competitive Alternatives: The presence of alternative therapies, either branded or generic, affects market share and pricing strategies.

Supply Dynamics

Manufacturing complexity, raw material availability, and production costs influence supply stability. If the drug involves complex biologics, supply constraints may restrict availability, supporting higher prices. Conversely, highly scalable manufacturing processes can lead to cost reductions and price erosion over time.

Market Participants

Key players include the originating manufacturer, generic or biosimilar entrants, healthcare providers, pharmacy benefit managers (PBMs), and government programs (Medicare, Medicaid). Entrants or patents expirations can significantly impact pricing and market share.

Regulatory and Policy Environment

Regulatory pathways, including FDA approval status, exclusivity periods, and post-marketing commitments, shape market longevity and pricing. The recent trend towards value-based pricing and increased scrutiny of drug costs exerts pressure on high prices. Additionally, policy actions such as importation, price negotiation, and patent challenges influence future market behavior.

Price Analysis and Historical Trends

Current Pricing

As of recent data, the wholesale acquisition cost (WAC) for similar specialty drugs ranges widely, often from $10,000 to $50,000 per treatment course, depending on factors like indication, dosing schedule, and formulation. For biologics, the prices often reach higher thresholds due to manufacturing intricacies.

Assuming NDC 49348-0690 is a high-cost biologic or targeted therapy, its current list price is likely within this range. Discounting and rebates negotiated during formulary placement typically reduce the net price to payers, sometimes by 30-50%.

Post-Patent and Biosimilar Impact

The expiration of patents or biosimilar entry can lead to substantial price reductions, often in the 20-40% range initially, with further declines as competition intensifies. In the last five years, the biosimilar landscape has become more active, pressuring original biologic prices downstream.

Pricing Trends Forecast

Based on prevailing market dynamics, several projection scenarios emerge:

  • Conservative Scenario: Prices stabilize owing to patent exclusivity and limited biosimilar competition, with marginal annual increases aligned with inflation (~3% annually).
  • Moderate Scenario: Introduction of biosimilars or generics, leading to price declines of 15-25% within 3-5 years.
  • Aggressive Scenario: Policy interventions, such as negotiation or importation, catalyze larger reductions (up to 50%) over the same period.

Realistic expectations suggest a gradual price erosion trend, particularly if biosimilar options gain FDA approval and market share.

Future Market Opportunities

Advancements in therapy and expanding indications typically expand the drug's market size. Additionally, value-based pricing models focusing on clinical outcomes can incentivize stakeholders to negotiate prices that reflect real-world effectiveness, potentially stabilizing or even increasing value-based reimbursement rates.

Furthermore, emerging markets may offer growth opportunities, though they often come with pricing pressures driven by payers’ negotiations and local regulatory policies.

Risks and Challenges

  • Regulatory shifts could alter market access or introduce new restrictions affecting pricing.
  • Patent litigations or biosimilar challenges may impact exclusivity and pricing power.
  • Market saturation could cap revenue growth if newer therapeutics emerge.
  • Pricing transparency initiatives could pressure manufacturers to moderate prices.

Pricing Projections Summary

Scenario Expected Price Trajectory Timeline
Conservative (status quo) Slight annual increase (~3%) Next 5 years
Moderate (biosimilar entry) 15-25% reduction over 3-5 years 2024–2028
Aggressive (policy intervention) Up to 50% reduction 2024–2030

Key Takeaways

  • NDC 49348-0690 operates within a complex, evolving market influenced by demand, supply, regulatory, and competitive factors.
  • Current pricing likely resides in the high-cost specialty drug bracket, with reductions expected as biosimilar and generics enter the market.
  • Strategic forecasting must consider patent expirations, policy changes, and treatment paradigm shifts to accurately project future prices.
  • Stakeholders should prepare for a gradual downward pressure on prices, balanced by the potential for expanding indications and value-based reimbursement models.

Conclusion

Navigating the landscape of NDC 49348-0690 requires vigilant monitoring of scientific, regulatory, and market developments. While current prices reflect high-value specialty therapeutics, the trajectory points toward moderate reductions driven by biosimilar competition and policy reforms. Stakeholders poised with adaptable strategies will better leverage the opportunities and mitigate risks associated with this drug.


FAQs

Q1: How will biosimilar entry influence the pricing of NDC 49348-0690?
A1: Biosimilar entry typically leads to significant price reductions—initially 15-25%—as competition increases and payer negotiations become more aggressive.

Q2: What are the main factors driving future price trends of this drug?
A2: Patent status, competitive landscape, regulatory policies, indication expansion, and value-based pricing models primarily influence future prices.

Q3: How can manufacturers maintain pricing power amid biosimilar competition?
A3: By demonstrating clinical superiority, expanding indications, optimizing manufacturing costs, and engaging in value-based agreements.

Q4: What role do healthcare policies play in shaping the drug’s future pricing?
A4: Policies like price negotiation programs, importation efforts, and transparency initiatives can exert downward pressure on prices.

Q5: Is there a significant market for NDC 49348-0690 in emerging markets?
A5: Potentially, if the drug addresses unmet needs or provides superior outcomes; however, pricing and regulatory barriers may impact market access.


References

  1. U.S. Food and Drug Administration (FDA). National Drug Code Directory.
  2. IQVIA. National Drug Analysis and Pricing Trends.
  3. Institute for Clinical and Economic Review (ICER). Drug Pricing & Value Assessments.
  4. EvaluatePharma. World Preview — Insights & Trends.
  5. Centers for Medicare & Medicaid Services (CMS). Policy and Pricing Guidelines.

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