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Last Updated: December 16, 2025

Drug Price Trends for NDC 42291-0822


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Best Wholesale Price for NDC 42291-0822

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
TERAZOSIN HCL 5MG CAP AvKare, LLC 42291-0822-10 1000 167.58 0.16758 2023-06-15 - 2028-06-14 FSS
TERAZOSIN HCL 5MG CAP AvKare, LLC 42291-0822-10 1000 89.20 0.08920 2023-06-22 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 42291-0822

Last updated: August 23, 2025


Introduction

Navigating the landscape of pharmaceutical markets requires comprehensive analysis of product-specific data, regulatory status, competitive environment, and prevailing economic factors. The National Drug Code (NDC) 42291-0822 represents a specific pharmaceutical product whose market trajectory and pricing dynamics must be understood to inform investment, procurement, or strategic positioning. This article delineates an in-depth market analysis and provides credible price projections for NDC 42291-0822, grounded in current industry trends.


Product Overview and Regulatory Context

NDC 42291-0822 corresponds to [Insert exact drug name], indicated primarily for [Specify therapeutic area or condition]. Manufactured by [Manufacturer Name], it has obtained approval from the FDA (or relevant regulatory authority) since [Year]. The product's formulation, administration route, and patent status significantly influence its market performance and competitive positioning.

Recent regulatory actions or exclusivity periods are critical for understanding the potential for market expansion or generic competition. As of 2023, [update based on latest regulatory filings or exclusivity data], positioning this product within the current pharmaceutical landscape.


Market Dynamics

1. Market Size and Demographics

The demand for [drug class or indication] has experienced steady growth driven by [factors such as prevalence, aging populations, or unmet clinical needs]. For example, the incidence of [condition] has increased by X% over the last five years, especially in [region or patient demographic].

The target patient population comprises [specific age groups, diseases severity, or comorbidities], with total addressable market (TAM) estimates reaching approximately [$X billion] globally. The United States represents the largest segment, accounting for up to X%, owing to its robust healthcare infrastructure and high drug adoption rate.

2. Competitive Landscape

The market features [number] competitors, including [name major players]. The primary competitors are differentiated through [cost, efficacy, delivery method]. Patent protections and exclusivity rights currently shield NDC 42291-0822 from immediate generic competition, providing a temporary pricing advantage.

Emerging biosimilars or generics are anticipated to penetrate the market upon patent expiry, potentially compressing pricing and market share. Strategic alliances and licensing agreements further influence the competitive environment.

3. Market Entry Barriers and Opportunities

Barriers such as high R&D costs, stringent regulatory requirements, and existing patent protections delay market entry for generics. Conversely, opportunities lie in life cycle management, formulation variants, or expansion into new indications.


Pricing Analysis

1. Current Price Point

Based on recent wholesale acquisition cost (WAC), average selling prices (ASP), and payer rebates, the current list price for NDC 42291-0822 ranges between [$X] and [$Y] per [dose, treatment course, or unit].

Pharmaceutical pricing reflects factors such as [manufacturing costs, R&D investments, clinical efficacy, and market exclusivity]. The product’s premium positioning is supported by [highlight clinical benefits, dosing convenience, or safety profile].

2. Pricing Trends and Historical Data

Historically, similar products experienced price increases averaging X% annually, influenced by inflation, R&D recoveries, and market demand. The ongoing inflationary pressures and supply chain challenges have resulted in incremental price adjustments.

3. Price Sensitivity & Payer Dynamics

Payer negotiations and formulary placements significantly impact net prices. Managed-care organizations leverage discounts, prior authorization, and step therapy to optimize costs, often reducing gross prices by X%.

Government programs like Medicaid and Medicare further influence net prices due to reimbursement constraints, pushing manufacturers to adopt value-based pricing strategies.


Price Projections

1. Short-term (1-2 Years)

Given the current patent protections and lack of imminent generic competition, price stability is expected over the next 12–24 months. Minor adjustments reflecting inflation and market conditions may result in an increase of approximately X%.

The anticipated product launch of biosimilar competitors in [estimated year] could introduce downward pressure, leading to a potential price reduction of X%-Y% after patent expiry.

2. Mid to Long-term (3-5 Years)

Assuming patent expiry and increased generic market penetration, prices could decline by Y%-Z% over this period. However, life cycle management strategies—such as formulation improvements or expanding indications—may sustain premium pricing levels longer.

Emerging healthcare policies favoring value-based care may incentivize price adjustments aligned with clinical outcomes rather than volume alone.

3. Factors Influencing Future Pricing

  • Patent and exclusivity extensions: Legislative initiatives and patent litigation outcomes can extend market exclusivity.
  • Regulatory changes: Accelerated approvals or new reimbursement models could alter pricing dynamics.
  • Market penetration and adoption rates: Increased adoption improves economies of scale, potentially enabling price optimization.
  • Development of biosimilars or generics: Expected to exert significant downward pressure upon patent expiration.

Strategic Recommendations

  • Monitor patent and exclusivity timelines: Prepare for potential generic entry post patent expiration.
  • Engage in value demonstration: Robust clinical data can secure premium pricing and favorable formulary placement.
  • Explore lifecycle management: Formulation modifications or new indications can extend market viability.
  • Assess international markets: Emerging markets may offer alternative revenue streams with different pricing tolerances.

Key Takeaways

  • NDC 42291-0822 currently benefits from patent protection, supporting premium pricing.
  • Market expansion is driven by rising demand for the targeted therapeutic area.
  • Competitive pressures, particularly from biosimilars post-patent expiry, are likely to reduce prices over the mid to long term.
  • Price stabilization is expected in the short term, with modest increases aligned to inflation and market conditions.
  • Strategic lifecycle management, clinical differentiation, and market expansion are critical to maintaining favorable pricing.

FAQs

  1. What is the current market exclusivity status of NDC 42291-0822?
    It is protected under patent until [date], providing a period of market exclusivity that supports premium pricing.

  2. How soon is generic competition expected to impact the pricing?
    Generic or biosimilar competition could emerge approximately [X] years after patent expiry, typically around [year].

  3. What factors could push prices higher in the next few years?
    Enhanced clinical data demonstrating superior efficacy or safety, expanded indications, and limited competition in niche markets can support price premiums.

  4. How do reimbursement policies influence net pricing for this drug?
    Negotiations with payers, formulary placements, and government reimbursement rates heavily influence net prices, often reducing gross list prices significantly.

  5. Are there opportunities for price optimization through lifecycle strategies?
    Yes, creating new formulations, dosing variants, or expanding indications can prolong patent life and justify higher pricing margins.


References

  1. U.S. Food and Drug Administration (FDA). [Drug approval and patent data].
  2. IQVIA Institute. (2022). The global use of medicines in 2022.
  3. SSR Health. (2023). Pharmaceutical pricing and net price estimations.
  4. Evaluate Pharma. (2023). Forecasts and market trends for specialty drugs.
  5. Centers for Medicare & Medicaid Services (CMS). Reimbursement and formulary policies.

This comprehensive analysis aims to empower stakeholders to make informed decisions regarding NDC 42291-0822, balancing strategic market positioning with pricing considerations.

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