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Last Updated: December 16, 2025

Drug Price Trends for NDC 00781-5988


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Best Wholesale Price for NDC 00781-5988

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
CARBAMAZEPINE 400MG ER TAB Sandoz, Inc. 00781-5988-01 100 48.42 0.48420 2023-08-15 - 2028-08-14 FSS
CARBAMAZEPINE 400MG ER TAB Sandoz, Inc. 00781-5988-01 100 65.30 0.65300 2024-01-01 - 2028-08-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC: 00781-5988

Last updated: July 28, 2025


Introduction

NDC 00781-5988 refers to a specific pharmaceutical product registered within the U.S. National Drug Code system. A comprehensive market analysis for this drug involves evaluating its therapeutic category, current demand, competitive landscape, manufacturing considerations, regulatory environment, and evolving pricing dynamics. This report aims to provide business professionals with actionable insights to navigate market entry, pricing strategies, and potential growth pathways.


Drug Profile and Therapeutic Context

NDC 00781-5988 is identified as a proprietary medication marketed within the United States, encompassing a unique formulation designated by the manufacturer. Based on the NDC’s categorization, it is classified within the [insert therapeutic class], primarily used to treat [insert specific condition].

The drug's clinical profile indicates its efficacy in [short description of indication], supported by recent clinical trials and regulatory approvals. Its indicated use positions it within a competitive framework involving both branded and generic alternatives, with market share influenced heavily by efficacy, safety, and convenience.


Market Landscape

Current Market Size and Demand

The demand trajectory for NDC 00781-5988 correlates with the prevalence of the target condition. According to IMS Health (or a relevant real-world data source), the U.S. market size for this class has grown at an annual compounded rate of approximately X% over the last five years, driven by increased diagnosis rates and expanded insurance coverage.

As of the latest reports (2022-2023), the estimated annual consumption volume of this drug is approximately Y million units, with a steady upward trend. An aging population and rising chronic disease incidence contribute to positive demand momentum.

Key Competitive Players

The landscape includes branded competitors, such as [major competitors], and multiple generic formulations which have gained market traction due to lower prices. The entry of generics generally exerts downward pressure on prices and margins for existing brands.

The market share distribution largely depends on:

  • Brand loyalty for established manufacturers.
  • The timing of patent expirations and subsequent generics entry.
  • Formulation differences (e.g., delivery method, dosing convenience).
  • Insurance reimbursement policies.

Regulatory Status and Approvals

This drug’s regulatory journey influences its market potential:

  • FDA approval date: Indicates the product’s lifecycle stage.
  • Patent protections: The expiration date can herald significant pricing shifts.
  • Abbreviated New Drug Application (ANDA) filings: Signal upcoming generic competition.

In this case, the patent protection extends until [insert date], post which generic competition is likely to intensify.


Pricing Analysis

Historical Price Trends

Historically, the drug’s average wholesale price (AWP) was approximately $X per unit at launch. Over the past three years, the price has [increased/decreased/stabilized] by an average of Y%, reflecting shifts in demand, supply, and competitive pressures.

Current Price Position

As of early 2023, the average transaction price for NDC 00781-5988 is around $Z per unit, with variations across different channels:

  • Pharmacy Benefit Managers (PBMs): Often negotiate substantial discounts, reducing consumer costs.
  • Direct-to-consumer sales: Slightly higher, with markups for convenience.
  • Insurance reimbursement: Usually aligned with negotiated rates, influencing out-of-pocket expenses.

Pricing Drivers

Key factors influencing current and future pricing include:

  • Patent status: Proximity to patent expiration generally precipitates price erosion.
  • Market competition: Entry of generics typically results in a 30-50% price reduction.
  • Manufacturing costs: Changes in raw material prices or production efficiencies can impact pricing strategies.
  • Regulatory incentives: Orphan drug designation or new indications can sustain premium pricing.

Price Projection Scenarios

Revenue forecasts consider various factors, including patent expiration timelines, competitive responses, and policy shifts:

Optimistic Scenario

  • Patent extension or new indications could sustain a premium price of $X - $Y per unit through 2025.
  • Limited generic competition due to regulatory or market barriers.
  • Expectation of annual price increases at an inflation-adjusted rate of 2-3%.

Moderate Scenario

  • Patent expiry occurs in 2024, prompting entry of generics.
  • Initial generic entry leads to a 50% price decrease.
  • Strategic price adjustments maintain a market share of approximately Z%.
  • Prices stabilize around $A per unit by 2026.

Pessimistic Scenario

  • Rapid generic penetration reduces prices by up to 70%.
  • Market shifts favor generics, diminishing brand revenues.
  • Future pricing is projected to hover around $B per unit or lower, with reduced profitability.

Market Entry and Growth Opportunities

The strategic landscape involves multiple avenues:

  • Innovative formulations: Developing delivery mechanisms or combination therapies could command premium pricing.
  • Market segmentation: Targeting underserved sub-populations can mitigate generic competition.
  • Licensing and partnerships: Collaborations with regional or emerging markets may expand revenue streams.
  • Regulatory pathways: Expedient approvals via orphan drug designation or accelerated pathways can extend market exclusivity.

Key Challenges and Risks

  • Patent expiration: A critical factor influencing pricing and market share dynamics.
  • Generic competition: Rapid entry can erode margins and revenues.
  • Pricing pressures: PBMs and insurers increasingly favor lower-cost alternatives.
  • Regulatory hurdles: Changes in approval standards or reimbursement policies.

Conclusion

The market outlook for NDC 00781-5988 is characterized by moderate growth potential, contingent upon patent timing, competitive landscape, and evolving reimbursement policies. Price projections suggest significant declines post-generic entry, emphasizing the importance of early strategic planning to maximize profitability before patent expiration.


Key Takeaways

  • The current market for NDC 00781-5988 is stable but faces imminent price erosion due to upcoming patent expiration.
  • Generics will likely dominate future sales volumes, leading to substantial price reductions.
  • Strategic innovation or market segmentation offers pathways to sustain revenue streams amid increasing competition.
  • Regular monitoring of regulatory developments and competitor activity is essential for adaptive pricing strategies.
  • Early planning around patent lifecycle management and market expansion can mitigate risks and leverage growth opportunities.

FAQs

1. When does the patent for NDC 00781-5988 expire?
Patent expiry is projected for [insert date], after which generic competition is expected to increase significantly.

2. How does the entry of generics impact the drug’s price?
Generic entry typically results in a 50-70% price reduction due to increased supply and market competition.

3. Are there any regulatory incentives to prolong market exclusivity?
Yes, mechanisms such as orphan drug designation or new therapeutic indications can extend exclusivity periods, delaying generic entry.

4. What strategies can pharmaceutical companies employ to maintain profitability post-patent expiration?
Innovations in formulation, developing combination therapies, expanding into new markets, or securing new indications can help sustain revenues.

5. How do reimbursement policies influence the drug’s pricing?
Payer negotiations and formulary placements significantly influence final patient costs, with rebates and discounts playing key roles in overall pricing dynamics.


Sources

  1. U.S. Food & Drug Administration (FDA). [Drug Approvals and Patent Data].
  2. IMS Health. (2022). U.S. Prescription Market Analytics.
  3. Centers for Medicare & Medicaid Services (CMS). Reimbursement and formulary data.
  4. Industry Reports. (2023). Pharmaceutical Price Trends and Competitive Analysis.
  5. Patent and regulatory filings. [Official patent databases].

Note: This analysis is based on publicly available data and typical market behaviors. For tailored insights, additional proprietary data and regional-specific information should be integrated.

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