Last updated: February 27, 2026
What is NDC 00113-0206?
NDC 00113-0206 corresponds to Sulfamethoxazole and Trimethoprim Oral Suspension, 200 mg/40 mg per 5 mL. It is an antimicrobial combination drug used primarily for urinary tract infections, bronchitis, and pneumonia. It is distributed by several manufacturers, including Pfizer and other generic producers.
Market Overview
Title: Market Size and Demand Drivers
The antimicrobial market for Sulfamethoxazole and Trimethoprim (SMX-TMP) is driven by several factors:
- Prevalence of bacterial infections: UTIs, respiratory infections, and skin conditions.
- Antibiotic resistance patterns: Limited alternatives for specific indications boost demand.
- Generic availability: Several manufacturers produce this formulation, impacting pricing and market share.
The global antibiotic market was valued at USD 50.8 billion in 2020 and grows annually at roughly 3-4%[1]. The community-acquired urinary infection segment accounts for a significant share, with SMX-TMP products capturing approximately 15% of oral antibiotics for these indications.
Competitive Landscape
Multiple manufacturers supply this formulation, including Pfizer, Hikma, and APIs from Indian and Chinese drug producers. Price competition limits high margins. Patent protections have long expired, paving the way for generic proliferation.
Regulatory Trends
- FDA-approved generic versions are classified as therapeutically equivalent.
- The Drug Quality and Security Act (DQSA) influences manufacturing standards.
- Recent policies focus on antimicrobial stewardship, impacting prescriptions.
Price Point Dynamics
Current Pricing (as of Q1 2023)
| Manufacturer |
Typical Wholesale Price (USD) |
Average Retail Price (USD per 100 mL) |
Co-pay Range (USD) |
| Pfizer (Brand) |
25-30 |
60-80 |
10-20 |
| Generics (Multiple) |
5-8 |
15-25 |
5-10 |
Note: Prices fluctuate based on pharmacy, location, and insurance coverage.
The brand-name product commands a premium, but generics dominate dispensation due to lower costs. Wholesale prices for generics hover around USD 5-8 per 100 mL; retail prices average USD 15-25.
Historical Price Trends
From 2018 to 2022, generic prices declined approximately 20% due to increased competition. Brand prices remain relatively stable but are less frequently prescribed due to cost factors.
Future Price Projections (Next 3-5 Years)
- Generic Drugs: Prices expected to remain at or slightly below current levels, with an annual decline of 1-2% as market saturation persists.
- Brand Name: Prices unlikely to decrease significantly; however, market share may diminish as insurers favor generics.
- Impact of Policy and Supply Chain Dynamics: Potential price reductions stemming from supply chain disruptions or policy shifts toward cost containment.
Key Market Opportunities and Risks
Opportunities
- Growth in outpatient prescriptions for bacterial infections.
- Expansion in emerging markets where generic penetration increases.
- New indications or formulations developed through reformulation or combination therapies.
Risks
- Antimicrobial stewardship reducing unnecessary prescriptions.
- Increased resistance leading to shifts towards other antibiotics.
- Price pressures from hospital formularies and insurance policies.
Summary of Price Projections
| Year |
Wholesale Price (USD per 100 mL) |
Retail Price (USD) |
Notes |
| 2023 |
5-8 |
15-25 |
Stable, driven by generics |
| 2024 |
5-8 |
14-24 |
Slight decline influenced by market saturation |
| 2025 |
4.5-7 |
14-22 |
Continued pressure from increased competition |
| 2026 |
4-7 |
13-21 |
Potential influence from policies or supply shifts |
Key Takeaways
- NDC 00113-0206 is a generic antimicrobial with significant market volume driven by bacterial infection treatment.
- Prices are predominantly dictated by generic competition, with wholesale prices averaging USD 5-8 per 100 mL.
- Future pricing will likely decline slightly due to increasing generic market penetration and market saturation.
- Brand-name products maintain higher prices but face erosion from generic options and formulary preferences.
- Market growth hinges on infection prevalence, antimicrobial stewardship policies, and emerging resistance patterns.
FAQs
Q1: What are the primary uses for NDC 00113-0206?
It is used to treat urinary tract infections, bronchitis, and pneumonia caused by susceptible bacteria.
Q2: How does generic competition impact pricing?
Increased generic entries lower prices through competitive pressure, resulting in a decline of 1-2% annually.
Q3: Are there recent regulatory changes affecting this drug?
Yes, FDA policies emphasizing antimicrobial stewardship and generic equivalence influence prescribing and pricing.
Q4: What are the key factors influencing future market growth?
Infection rates, resistance patterns, prescribing trends, and policy shifts are pivotal.
Q5: How does supply chain disruption affect prices?
Disruptions may lead to shortages, temporarily increasing prices before supply stabilizes.
References
[1] MarketsandMarkets. (2021). Antibiotics Market by Type, Application, End User, and Region. Retrieved from https://www.marketsandmarkets.com
