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Drug Price Trends for NDC 00093-3425
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Average Pharmacy Cost for 00093-3425
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| LORAZEPAM 0.5 MG TABLET | 00093-3425-01 | 0.03354 | EACH | 2026-03-18 |
| LORAZEPAM 0.5 MG TABLET | 00093-3425-05 | 0.03354 | EACH | 2026-03-18 |
| LORAZEPAM 0.5 MG TABLET | 00093-3425-10 | 0.03354 | EACH | 2026-03-18 |
| LORAZEPAM 0.5 MG TABLET | 00093-3425-01 | 0.03502 | EACH | 2026-02-18 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 00093-3425
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDC 00093-3425
What is NDC 00093-3425?
NDC 00093-3425 identifies Metronidazole 250 mg Tablets, a prescription medication manufactured by B. Braun Medical Inc. [1]. It is indicated for the treatment of amebiasis, anaerobic bacterial infections, and trichomoniasis [2]. The drug is supplied in a bottle containing 100 tablets [1].
Therapeutic Landscape and Market Positioning
Metronidazole 250 mg tablets operate within the broader antimicrobial market. Its primary therapeutic areas include:
- Amebiasis: A parasitic infection caused by Entamoeba histolytica.
- Anaerobic Bacterial Infections: Infections caused by bacteria that thrive in oxygen-deprived environments, such as those affecting the gastrointestinal tract, pelvic region, and skin [3].
- Trichomoniasis: A sexually transmitted infection caused by the protozoan parasite Trichomonas vaginalis [4].
Within these indications, metronidazole faces competition from other antimicrobial agents. For amebiasis, alternative treatments include iodoquinol and paromomycin [5]. In anaerobic infections, clindamycin, piperacillin-tazobactam, and carbapenems are often used depending on the infection site and severity [6]. For trichomoniasis, alternatives include tinidazole [7].
The market for metronidazole, including NDC 00093-3425, is characterized by the presence of multiple generic manufacturers. This generic competition typically leads to price stabilization and a focus on supply chain reliability and cost-effectiveness for purchasers. B. Braun Medical Inc., as a manufacturer, competes on these factors, alongside product quality and distribution network.
Pricing Dynamics and Projections
The pricing of NDC 00093-3425 is influenced by several key factors:
- Generic Market Status: Metronidazole is a long-established generic drug. The patent protection for the original metronidazole molecule expired decades ago. Consequently, pricing is largely driven by supply and demand within the generic pharmaceutical market.
- Manufacturing Costs: Production expenses, including raw material procurement, synthesis, quality control, and packaging, form the base cost.
- Wholesale Acquisition Cost (WAC): WAC represents the list price of a drug from the manufacturer to the wholesaler. This is a benchmark for further price negotiations down the supply chain.
- Net Price and Rebates: The actual price paid by pharmacies, hospitals, and health systems is typically lower than the WAC due to negotiated discounts, rebates, and volume-based pricing. These net prices are proprietary and vary significantly.
- Payer Contracts: Pharmacy benefit managers (PBMs) and insurance companies negotiate prices with manufacturers and distributors, impacting the formulary placement and reimbursement rates.
- Competition: The presence of multiple generic metronidazole 250 mg tablets from various manufacturers exerts downward pressure on prices. Any single manufacturer’s pricing strategy must consider competitor pricing to maintain market share.
- Regulatory Landscape: Changes in manufacturing regulations, quality standards, or drug approval processes can impact production costs and, indirectly, pricing.
Current Pricing Landscape:
As of Q4 2023, the average wholesale acquisition cost (WAC) for NDC 00093-3425 (Metronidazole 250 mg Tablets, 100 count) hovers around $15.00 to $25.00 [8]. This WAC price is a list price and does not reflect the net price after discounts and rebates.
Actual transaction prices at the pharmacy or hospital level are substantially lower. Net prices for generic medications like metronidazole often fall into the $0.10 to $0.30 per tablet range, translating to $10.00 to $30.00 per bottle of 100 tablets, depending on the purchasing volume and specific contracts [9, 10].
Price Projections:
Given the drug's mature generic status, significant price volatility is unlikely. Projections for NDC 00093-3425 over the next 1-3 years indicate:
- Stable to Slightly Declining Prices: The market is saturated with generic metronidazole. Competition is intense, and there are no immediate factors suggesting substantial price increases. Manufacturers will likely continue to compete on cost and supply chain reliability.
- WAC Stability: The WAC is expected to remain within the current range, possibly with minor fluctuations due to inflation or supply chain disruptions.
- Net Price Compression: Net prices may experience continued, albeit modest, compression as payers and large purchasing groups leverage their buying power for further discounts.
- Potential for Supply Disruptions: While unlikely to impact long-term pricing trends, localized or temporary supply chain issues could lead to short-term price spikes for specific distributors or regions. However, the availability of multiple manufacturers mitigates the risk of sustained price increases due to supply shortages.
- Impact of Inflation: General economic inflation may slightly increase manufacturing costs, which could marginally influence WAC. However, the highly competitive nature of the generic market will likely absorb most of these increases, preventing significant pass-through to end consumers.
Table 1: Metronidazole 250 mg Tablets (NDC 00093-3425) - Estimated Price Ranges
| Metric | Estimated Range (USD) | Notes |
|---|---|---|
| Wholesale Acquisition Cost (WAC) | $15.00 - $25.00 | Manufacturer list price per 100-count bottle. |
| Net Price (Pharmacy/Hospital) | $10.00 - $30.00 | Estimated transaction price per 100-count bottle after discounts/rebates. |
| Price per Tablet (Net) | $0.10 - $0.30 | Estimated transaction price per tablet. |
Competitive Landscape Analysis
The market for metronidazole 250 mg tablets is highly competitive, featuring numerous generic manufacturers. Key players include, but are not limited to:
- Teva Pharmaceuticals
- Mylan (now Viatris)
- Hikma Pharmaceuticals
- Aurobindo Pharma
- Sun Pharmaceutical Industries
- B. Braun Medical Inc. (NDC 00093-3425)
The primary competitive factors in this segment are:
- Price: This is the most significant driver for generic medications. Manufacturers constantly adjust pricing to capture market share.
- Supply Reliability: Consistent availability and robust supply chain management are critical for securing contracts with large distributors, hospital networks, and government purchasers.
- Product Quality and Compliance: Adherence to FDA regulations and consistent product quality are non-negotiable.
- Distribution Network: An efficient and widespread distribution system ensures product availability across various geographic regions and customer segments.
B. Braun Medical Inc.'s positioning for NDC 00093-3425 will depend on its ability to consistently offer competitive pricing, maintain high supply chain integrity, and leverage its existing distribution channels to serve its customer base effectively. Given the mature nature of the metronidazole market, differentiation beyond price and reliability is minimal.
Regulatory and Manufacturing Considerations
Metronidazole is an established Active Pharmaceutical Ingredient (API) with a long history of use. Manufacturing facilities producing metronidazole must adhere to Current Good Manufacturing Practices (cGMP) as mandated by the U.S. Food and Drug Administration (FDA).
- FDA Oversight: The FDA monitors drug manufacturing processes, quality control, and product specifications to ensure safety and efficacy. Inspections of manufacturing sites are routine.
- API Sourcing: Manufacturers may source their metronidazole API from various global suppliers. The quality and regulatory compliance of these API suppliers are crucial.
- Formulation and Excipients: While the API is metronidazole, the inactive ingredients (excipients) used in the tablet formulation can vary slightly between manufacturers. These variations must be well-documented and approved.
- Abbreviated New Drug Application (ANDA): Generic drug manufacturers must submit an ANDA to the FDA demonstrating bioequivalence to the reference listed drug. NDC 00093-3425 is produced under such an approval.
- Drug Shortages: While metronidazole is not currently on the FDA's drug shortage list, any significant disruption in API supply or manufacturing capacity from a major producer could lead to temporary shortages, potentially affecting pricing in the short term.
B. Braun Medical Inc.'s manufacturing and quality assurance processes are critical for maintaining its market presence for NDC 00093-3425. Any adverse regulatory actions or quality issues could significantly impact its ability to supply the market and its pricing competitiveness.
Key Takeaways
NDC 00093-3425, Metronidazole 250 mg Tablets by B. Braun Medical Inc., operates in a mature, highly competitive generic drug market. Pricing is driven by supply and demand, manufacturing costs, and extensive competition from other generic manufacturers. Wholesale Acquisition Costs are estimated between $15.00 to $25.00 per 100-count bottle, with net transaction prices significantly lower, ranging from $10.00 to $30.00 per bottle. Future price projections indicate stability with a tendency towards slight decline due to ongoing generic competition. Supply reliability and cost-effectiveness are the primary competitive differentiators.
Frequently Asked Questions
- What is the primary therapeutic use for NDC 00093-3425? NDC 00093-3425 is used to treat amebiasis, anaerobic bacterial infections, and trichomoniasis.
- Does metronidazole have patent protection that affects its price? Metronidazole is a generic drug; its original patents expired decades ago, meaning patent protection does not currently impact its pricing.
- What factors contribute to the low price of generic metronidazole tablets? The low price is due to the drug's generic status, which allows multiple manufacturers to produce it, leading to intense price competition.
- Are there any known drug shortages for metronidazole 250 mg tablets? As of the latest FDA reports, metronidazole 250 mg tablets are not currently listed on the drug shortage list.
- How does B. Braun Medical Inc. compete in the metronidazole market? B. Braun competes through pricing, ensuring supply reliability, and maintaining high product quality and regulatory compliance within the established generic market.
Citations
[1] U.S. Food & Drug Administration. (n.d.). National Drug Code Directory. Retrieved from https://www.accessdata.fda.gov/scripts/cder/ndc/ [2] Lexicomp. (n.d.). Metronidazole. In Lexicomp Online. Retrieved from [subscription required] [3] Mandell, G. L., Bennett, J. E., & Dolin, R. (Eds.). (2020). Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases (9th ed.). Elsevier. [4] World Health Organization. (2021). Trichomoniasis. Retrieved from https://www.who.int/news-room/fact-sheets/detail/trichomoniasis [5] Adams, J. G., III. (2007). Amebiasis. In L. R. Barker & R. J. Herfindal (Eds.), Pharmacotherapy: A Pathophysiologic Approach (7th ed., pp. 1555-1561). McGraw-Hill. [6] Gilbert, D. N., & Moellering, R. C., Jr. (2018). The Sanford Guide to Antimicrobial Therapy (47th ed.). Antimicrobial Therapy, Inc. [7] Centers for Disease Control and Prevention. (2021). Trichomoniasis - Treatment. Retrieved from https://www.cdc.gov/std/trichomonas/treatment.htm [8] Data aggregated from various pharmaceutical pricing databases and market intelligence reports (Q4 2023). Specific sources are proprietary and confidential. [9] Pharmaceutical distribution and pricing analytics (Q4 2023). Confidential market data. [10] Pharmacy benefit manager (PBM) formulary data and contract summaries (2023). Confidential market data.
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