Drug Price Trends for PREDNISOLONE SOD PH

Average Pharmacy Cost for PREDNISOLONE SOD PH

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
PREDNISOLONE SOD PH 25 MG/5 ML	42799-0816-01	0.78891	ML	2024-12-18
PREDNISOLONE SOD PH 25 MG/5 ML	44523-0182-08	0.78891	ML	2024-12-18
PREDNISOLONE SOD PH 25 MG/5 ML	44523-0182-08	0.82255	ML	2024-11-20

Market Analysis and Price Projections for Prednisolone Sodium Phosphate

Introduction

Prednisolone sodium phosphate is a widely used glucocorticoid with anti-inflammatory, immunosuppressive, and other therapeutic properties. This article delves into the market analysis and price projections for this drug, highlighting key factors influencing its market dynamics.

Market Size and Growth

The market for prednisolone and its derivatives, such as prednisone, is substantial and growing. The prednisone market, which includes prednisolone sodium phosphate, is estimated to cross USD 9 billion by 2036, with a Compound Annual Growth Rate (CAGR) of around 5% during the forecast period of 2024-2036[4].

Key Drivers of Market Growth

Several factors are driving the growth of the prednisolone market:

Increasing Prevalence of Skin Diseases

Skin diseases, which can be caused by bacteria, viruses, fungi, or parasites, are a significant health issue globally. According to the World Health Organization, approximately 1.8 billion people worldwide suffer from skin disorders at any given time. This surge in skin diseases is a major driver for the increased demand for prednisolone and other glucocorticoids[4].

Growing Healthcare Investments

The healthcare sector is witnessing significant investments, particularly in hospitals. Hospitals are expected to generate the highest revenue share in the prednisone market, accounting for about 50% of the total revenue. This is due to the increasing number of patients with serious illnesses such as neurological, pulmonary, and cardiovascular diseases, who often require steroid treatments[4].

Regional Market Growth

The Asia Pacific region is anticipated to experience notable growth in the prednisone market. Factors contributing to this growth include the lack of physical activity and the rising prevalence of kidney disorders in this region. For instance, up to 434.3 million people in Asia are affected by chronic kidney disease (CKD), with China and India accounting for the majority of cases[4].

Price Trends for Prednisolone Sodium Phosphate

The prices of prednisolone sodium phosphate solutions vary based on concentration, volume, and vendor.

Current Pricing

As of 2024, the prices for different formulations of prednisolone sodium phosphate are as follows:

• Prednisolone 10 MG/5 ML Solution: Prices range from $1.96385 to $2.28195 per milliliter, depending on the vendor and the specific product code[2].
• Prednisolone 15 MG/5 ML Solution: Prices range from $0.10868 to $0.62670 per milliliter[2].
• Prednisolone Sodium Phosphate 25 MG/5 ML Solution: Prices are around $0.78891 per milliliter[2].

Price Projections

Given the growing demand and stable supply chain, prices for prednisolone sodium phosphate are expected to remain relatively stable or see a moderate increase. However, any significant changes in raw material costs, regulatory environments, or market competition could impact pricing.

Solubility and Bioavailability

The solubility and bioavailability of prednisolone sodium phosphate are crucial factors in its market acceptance and efficacy.

Solubility

Prednisolone sodium phosphate is highly soluble in water, which ensures good dissolution across a wide pH range (1 to 8). This high solubility is not considered a limiting factor for in vivo absorption[1][5].

Bioavailability

Oral prednisolone is approximately 70% bioavailable, with a peak plasma concentration (Tmax) reached within 1.0 to 2.6 hours after administration. This high bioavailability contributes to its effectiveness and market demand[3].

Market Challenges

While the market for prednisolone sodium phosphate is growing, there are several challenges to consider:

Regulatory Hurdles

Regulatory approvals and compliance can be complex and time-consuming. For instance, the CMDh referral procedure for Okrido, a product containing prednisolone sodium phosphate, highlighted the need for consensus among regulatory bodies[1].

Competition

The glucocorticoid market is competitive, with various formulations and brands available. This competition can influence pricing and market share.

Side Effects and Alternatives

Glucocorticoids, including prednisolone, can have significant side effects, which may lead to the development and preference for alternative treatments. This could impact market growth if safer alternatives become widely available.

Key Takeaways

• The prednisolone market, including prednisolone sodium phosphate, is expected to grow significantly due to increasing prevalence of skin diseases and other health issues.
• The Asia Pacific region is anticipated to see notable growth in the market.
• Prices for prednisolone sodium phosphate are expected to remain relatively stable, with potential moderate increases.
• High solubility and bioavailability of prednisolone sodium phosphate are key factors in its market success.
• Regulatory hurdles, competition, and potential side effects are challenges that need to be addressed.

FAQs

Q: What is the current market size of the prednisone market? A: The prednisone market size was over USD 6.32 billion in 2024 and is projected to reach USD 12.37 billion by 2037[4].

Q: What are the main drivers of the prednisolone market growth? A: The main drivers include the increasing prevalence of skin diseases, growing healthcare investments, and regional growth particularly in the Asia Pacific region[4].

Q: How soluble is prednisolone sodium phosphate? A: Prednisolone sodium phosphate is highly soluble in water, remaining in solution across the pH range of 1 to 8[1][5].

Q: What is the bioavailability of oral prednisolone? A: Oral prednisolone is approximately 70% bioavailable[3].

Q: What are the potential challenges for the prednisolone market? A: Regulatory hurdles, competition, and potential side effects are significant challenges for the market[1][4].

Sources

1. European Medicines Agency, "ANNEX II: Okrido Article 29 Referral," June 26, 2013.
2. DrugPatentWatch, "Drug prices and trends for prednisolone."
3. DrugBank, "Prednisolone: Uses, Interactions, Mechanism of Action."
4. Research Nester, "Prednisone Market Size & Share, Growth Forecasts 2036."
5. FIP, "Biowaiver monographs for immediate release solid oral dosage forms: Prednisolone."