Drug Price Trends for METRONIDAZOLE VAGINAL

Average Pharmacy Cost for METRONIDAZOLE VAGINAL

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
METRONIDAZOLE VAGINAL 0.75% GL	73473-0303-70	0.20818	GM	2025-04-23
METRONIDAZOLE VAGINAL 0.75% GL	00713-0575-71	0.20818	GM	2025-04-23
METRONIDAZOLE VAGINAL 0.75% GL	16714-0557-01	0.20818	GM	2025-04-23
METRONIDAZOLE VAGINAL 0.75% GL	45802-0139-70	0.20818	GM	2025-04-23

Market Analysis and Price Projections for Metronidazole Vaginal

Market Overview

The market for metronidazole, particularly in its vaginal formulation, is driven by several key factors, including the increasing incidence of bacterial and parasitic infections, advancements in healthcare, and the affordability and availability of the drug.

Market Size and Growth

The North America, Europe, and Asia-Pacific metronidazole market, which includes vaginal formulations, is projected to reach USD 390.59 million by 2031, growing at a significant CAGR from 2024 to 2031. This growth is largely attributed to the rising demand for effective treatments for bacterial vaginosis, amoebiasis, and other infections[1].

Form Type and Market Share

Metronidazole Vaginal Gel

Metronidazole vaginal gel is a prominent form of the drug, widely used for treating bacterial vaginosis and other vaginal infections. This formulation is part of the broader metronidazole market, where tablets and capsules dominate, but vaginal gels are also significant due to their specific application and efficacy.

• Cost and Availability: The cost for MetroGel-Vaginal, a common brand of metronidazole vaginal gel, is around $36 for a 70-gram supply, with generic versions available at lower prices, such as $32.16 for 70 grams[2][5].

Distribution Channels

The distribution of metronidazole vaginal gel is primarily through retail pharmacies, which hold the largest market share. This is due to the convenience and accessibility of retail pharmacies, making it easier for patients to obtain their prescription medications promptly.

• Retail Pharmacies: These pharmacies are the main distribution channel, driving the market growth due to their widespread presence and ease of access for consumers[1].

End Use

The human segment dominates the end-use market for metronidazole, including its vaginal formulations. This is driven by the increasing need for novel antibiotics to reduce disease recurrence and the advancement of healthcare solutions.

• Human Use: The human segment is expected to grow at a higher CAGR during the projected period, driven by factors such as the treatment of chronic diseases like bacterial vaginosis, amoebiasis, and other infections[1].

Cost-Effectiveness

Studies have shown that generic metronidazole is the most cost-effective treatment for bacterial vaginosis compared to branded products like MetroGel-Vaginal.

• Comparative Costs: A study comparing oral metronidazole and MetroGel-Vaginal found that the entire cost of treatment was significantly lower for generic metronidazole ($1.51) compared to MetroGel-Vaginal ($19.71)[3].

Pricing Projections

The pricing of metronidazole vaginal gel is expected to remain competitive, with generic versions offering significant cost savings.

• Current Pricing: The current price range for metronidazole vaginal gel is between $32.16 and $36.13 for a 70-gram supply, depending on the brand and pharmacy[2][5].
• Future Trends: With the increasing competition from generic versions and the growing demand for affordable healthcare solutions, prices are likely to remain stable or decrease slightly over the forecast period.

Patient Assistance and Discounts

Several programs and discount cards are available to help patients reduce the cost of metronidazole vaginal gel.

• Discount Cards: Programs like the Drugs.com Discount Card can save patients up to 80% on prescription medications, including metronidazole vaginal gel[2][5].
• Patient Assistance Programs: While specific patient assistance programs for MetroGel-Vaginal may not be available, healthcare providers may have information on other programs that can help reduce costs[2].

Clinical Efficacy and Safety

Metronidazole vaginal gel has been shown to be effective in treating bacterial vaginosis with minimal side effects.

• Clinical Studies: A study comparing metronidazole and MetroGel-Vaginal found successful treatment outcomes in 27 and 28 patients out of 30, respectively, with no significant complications reported[3].
• Pharmacokinetics: The pharmacokinetic profile of metronidazole vaginal gel, including its Cmax and AUC, has been found to be comparable to other marketed products, ensuring its efficacy and safety[4].

Geographical Market

The market for metronidazole vaginal gel is significant in regions such as North America, Europe, and Asia-Pacific, driven by the prevalence of bacterial and parasitic infections and the availability of healthcare infrastructure.

• Regional Growth: The Asia-Pacific region, particularly countries like India, has a significant need for metronidazole due to the high incidence of infections and government initiatives to improve healthcare accessibility and affordability[1].

Key Takeaways

• Market Growth: The metronidazole market, including vaginal formulations, is projected to reach USD 390.59 million by 2031.
• Cost-Effectiveness: Generic metronidazole is the most cost-effective treatment for bacterial vaginosis.
• Distribution: Retail pharmacies are the primary distribution channel.
• End Use: The human segment dominates the market.
• Pricing: Prices are competitive, with generic versions offering significant savings.
• Patient Assistance: Discount cards and patient assistance programs can help reduce costs.

FAQs

1. What is the projected market size for metronidazole in North America, Europe, and Asia-Pacific by 2031? The market is projected to reach USD 390.59 million by 2031[1].

2. Which form of metronidazole dominates the market? Metronidazole tablets or capsules dominate the market, but vaginal gels are also significant[1].

3. What is the cost of MetroGel-Vaginal? The cost for MetroGel-Vaginal is around $36 for a 70-gram supply, with generic versions available at lower prices[2][5].

4. What is the most cost-effective treatment for bacterial vaginosis? Generic metronidazole is the most cost-effective treatment for bacterial vaginosis[3].

5. Are there any patient assistance programs available for MetroGel-Vaginal? No specific patient assistance programs were found for MetroGel-Vaginal, but healthcare providers may have information on other programs[2].

Sources

1. Verified Market Research: North America, Europe And Asia-Pacific Metronidazole Market.
2. Drugs.com: MetroGel-Vaginal Prices, Coupons, Copay Cards & Patient Assistance.
3. PubMed: Oral metronidazole vs. Metrogel Vaginal for treating bacterial vaginosis.
4. FDA: 205223Orig1s000 - Metronidazole Gel: 10 Day Vaginal Irritation Study in Rabbits.
5. Drugs.com: Metronidazole topical Prices, Coupons, Copay Cards & Patient Assistance.