Drug prices and trends for METHADONE INTENSOL

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Drug Name	NDC	Price/Unit ($)	Unit	Date
METHADONE INTENSOL 10 MG/ML	00054-3553-44	0.52824	ML	2025-06-18
METHADONE INTENSOL 10 MG/ML	00054-3553-44	0.54473	ML	2025-05-21
METHADONE INTENSOL 10 MG/ML	00054-3553-44	0.54142	ML	2025-04-23
>Drug Name	>NDC	>Price/Unit ($)	>Unit	>Date

Last updated: January 2, 2025

Market Overview

The methadone market is poised for significant growth, driven by several key factors including the increasing prevalence of chronic pain, opioid dependency, and advancements in drug formulations.

Global Market Size: The methadone market was valued at over USD 172.86 million in 2024 and is projected to exceed USD 437.27 million by 2037, growing at a CAGR of 7.4% during the forecast period of 2025-2037[1].
Regional Growth: North America is expected to account for the largest revenue share, approximately 42% by 2037, due to the high incidence of drug addiction and chronic pain in the region[1].

Market Segmentation

By Mode of Administration

The market is segmented into oral solutions, tablets, intravenous injections, and others. The oral solution segment is anticipated to hold the largest market share, driven by the preference of the geriatric population for liquid methadone due to difficulties in swallowing tablets[1].
Oral Solutions: These are liquid methadone formulations prescribed for pain management and addiction treatment. They come in various strengths and are particularly favored by older patients[1].

By Application

Methadone is used in pain management, detoxification, and other applications.
Pain Management: The increasing prevalence of chronic pain, especially post-surgical pain, is a significant driver. For instance, around 20% of U.S. adults suffered from chronic diseases in 2019, with 4% experiencing severe chronic pain[1].
Detoxification: Methadone is widely used in opioid dependence treatment programs. Over 80 countries have established methadone maintenance therapy programs to combat rising overdose rates[4].

Market Dynamics

Drivers of Growth

Increasing Prevalence of Chronic Diseases: The growing number of patients suffering from chronic diseases, particularly among the geriatric population, is driving the demand for methadone[1][2][4].
Opioid Misuse: The rise in opioid dependency and the need for effective treatment options are significant drivers. In 2019, 70,630 deaths were caused by drug overdose in the United States alone[1][2].
Advancements in Drug Formulations: Innovations such as sustained-release tablets and injectable formulations are enhancing patient compliance and efficacy, further boosting market growth[4].

Challenges

Side Effects: Methadone is associated with several side effects, which can act as a restraint to market growth. However, advancements in formulations are aimed at reducing these side effects[2].

Regional Analysis

North America

This region is expected to dominate the market, driven by the high incidence of drug addiction and chronic pain. The U.S. Methadone Hydrochloride market is particularly strong due to supportive government initiatives and advancements in telemedicine platforms[1][4].

Asia-Pacific

The APAC region is anticipated to experience significant growth, driven by the large and growing geriatric population in countries like India and China. This demographic shift is expected to increase the demand for methadone in managing chronic diseases[1].

Europe

Europe is also a key market, with companies like Macfarlan Smith holding significant market shares due to their high-quality formulations and strong distribution networks[4].

Price Projections and Current Pricing

Current Pricing

The prices of methadone hydrochloride vary based on the form and dosage. For example, the cost of a 10 mg methadone HCL tablet can range from $0.17 to $0.18 per unit, while injectable formulations can range from $12.31 to $16.22 per ml[5].

Price Projections

Given the growing demand and advancements in drug formulations, prices are expected to remain stable or see a slight increase. However, the overall market value is projected to rise significantly. For instance, the global methadone market is expected to reach $184.8 million by 2030 from $126.6 million in 2023, growing at a CAGR of 5.5%[2].

Investment Analysis and Opportunities

The methadone market offers robust investment opportunities, particularly in expanding production facilities and developing new formulations. Companies like Tianjin Central Pharma have invested heavily in increasing production capacity, allocating $50 million for a new manufacturing plant in Asia[4].
Telemedicine and Digital Health: The expansion of telemedicine and e-prescription services is making it easier for patients to access methadone treatments, especially in underserved areas. This trend is expected to significantly boost market growth[4].

Future Outlook

The methadone market is poised for sustained growth, driven by increasing global awareness about opioid substitution therapies and advancements in drug formulations.
Sustained-Release Formulations: These are expected to revolutionize the market by ensuring prolonged therapeutic effects and reducing dosing frequency[4].
Injectable Formulations: These are gaining popularity in acute pain management, particularly in postoperative care settings[4].

Key Takeaways

The methadone market is growing rapidly due to the increasing prevalence of chronic pain and opioid dependency.
Oral solutions are expected to dominate the market due to their preference among the geriatric population.
North America and the Asia-Pacific region are key markets driven by demographic changes and increasing healthcare needs.
Advancements in drug formulations and telemedicine services are significant drivers of market growth.
The market is expected to reach significant values by 2030 and 2037, driven by a CAGR of around 5.5% to 7.4%.

FAQs

Q: What is the projected growth rate of the methadone market?

The methadone market is expected to grow at a CAGR of around 5.5% to 7.4% during the forecast period of 2025-2037[1][2].

Q: Which region is expected to dominate the methadone market?

North America is expected to account for the largest revenue share, driven by the high incidence of drug addiction and chronic pain in the region[1].

Q: What are the primary drivers of the methadone market?

The primary drivers include the increasing prevalence of chronic diseases, opioid misuse, and advancements in drug formulations[1][2][4].

Q: How is the geriatric population influencing the methadone market?

The growing geriatric population is driving the demand for methadone, particularly in the form of oral solutions, due to difficulties in swallowing tablets[1].

Q: What are the recent innovations in methadone formulations?

Recent innovations include sustained-release tablets and injectable formulations, which are designed to enhance patient compliance and efficacy[4].

Cited Sources:

Research Nester, "Methadone Market Size, Trends | Growth Analysis - 2037".
GlobeNewswire, "Methadone Market Set for Strong Growth Trajectory, Projected to Reach $184.8 Million by 2030".
GIIR, "Methadone Market: Current Analysis and Forecast (2022-2028)".
Global Growth Insights, "Methadone Hydrochloride Market Size and Trends Research [2025 ...]".
DrugPatentWatch, "Drug prices and trends for METHADONE HCL".

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