Drug Price Trends for KETOPROFEN ER

Average Pharmacy Cost for KETOPROFEN ER

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
KETOPROFEN ER 200 MG CAPSULE	00378-8200-01	6.61864	EACH	2025-02-19
KETOPROFEN ER 200 MG CAPSULE	00378-8200-01	6.61864	EACH	2025-01-22
KETOPROFEN ER 200 MG CAPSULE	00378-8200-01	6.61864	EACH	2024-12-18

Ketoprofen ER Market Analysis and Price Projections

Introduction to Ketoprofen ER

Ketoprofen ER (Extended Release) is a nonsteroidal anti-inflammatory drug (NSAID) known for its analgesic, antipyretic, and anti-inflammatory properties. It is commonly used for the management of the signs and symptoms of rheumatoid arthritis and osteoarthritis.

Market Dynamics

Growing Demand for Pain Management

The ketoprofen market is driven by the increasing prevalence of chronic diseases and an aging population, which are key factors in the rising demand for effective pain management solutions. The global market for ketoprofen is expected to witness significant growth due to these demographic changes[5].

Innovations in Drug Delivery

Advancements in drug delivery technologies, such as extended-release formulations and transdermal patches, are enhancing the effectiveness of ketoprofen. These innovations provide consistent pain relief over extended periods, improving patient outcomes and opening new revenue streams for pharmaceutical companies[5].

Personalized Medicine

The shift towards personalized medicine is transforming the way healthcare providers approach pain management. By leveraging genetic information and patient data, pharmaceutical companies are developing ketoprofen formulations that cater to specific patient needs, resulting in more effective and safer treatments[5].

Market Segmentation

By Type

The ketoprofen market is segmented into various types, including ketoprofen tablets, capsules, and gels. The extended-release capsules, such as ketoprofen ER, are designed to release the drug at a controlled rate, providing sustained pain relief over a longer period[3].

By Application

Ketoprofen ER is primarily used for pain management, particularly in the treatment of rheumatoid arthritis and osteoarthritis. Other applications include dysmenorrhea, gout, and general pain relief[3].

Pharmacokinetics and Clinical Pharmacology

Release Characteristics

Ketoprofen ER capsules are designed to resist dissolution in the low pH of gastric fluid but release the drug at a controlled rate in the higher pH environment of the small intestine. This results in a slower and more sustained release of the drug compared to immediate-release formulations[1].

Bioavailability and Half-Life

The systemic availability of ketoprofen ER capsules is approximately 90% when compared to IV administration. Steady-state concentrations are attained within 24 hours, with minimal accumulation of the drug after multiple doses. In elderly patients, the elimination half-life is prolonged by 54%, and total drug Cmax and AUC are higher compared to younger subjects[1].

Bioequivalence Studies

Bioequivalence studies have been conducted to compare different formulations of ketoprofen ER. For example, a study comparing a 150 mg extended-release tablet from LETI Laboratories to a reference product from Sanofi-Aventis showed that the test formulation was bioequivalent in terms of AUC and Cmax, falling within the 80% - 125% range[4].

Pricing and Cost Considerations

Current Pricing

The cost for ketoprofen 200 mg oral capsule, extended release, can range around $929 for a supply of 100 capsules, depending on the pharmacy and any applicable discounts or coupons[2].

Discount Programs and Patient Assistance

Patients can benefit from discount programs such as the Drugs.com Discount Card, which can save up to 80% or more off the cost of prescription medicines. These programs are not insurance plans but can significantly reduce the out-of-pocket costs for patients[2].

Market Projections

Growth Rate and Market Size

The ketoprofen market is anticipated to grow at a significant CAGR by 2031, driven by the increasing demand for pain management solutions and advancements in drug delivery technologies. The market size is expected to expand from its current value to a projected value of several million dollars by 2031[3][5].

Regional Analysis

The market is segmented into regions such as North America, Europe, Asia-Pacific, Middle East and Africa, and South & Central America. Each region is further sub-segmented by country, providing a detailed overview of the market trends and growth opportunities in each area[3].

Key Trends and Innovations

Sustainable Manufacturing Practices

The pharmaceutical industry is increasingly focusing on sustainable manufacturing practices, which is expected to influence the future of the ketoprofen market. Companies that adopt sustainable practices are likely to see positive impacts on their market position and profitability[5].

Strategic Partnerships and Mergers

Strategic partnerships between pharmaceutical companies and research institutions are fostering innovation in the ketoprofen market. These collaborations lead to the development of next-generation products and expand the range of available treatment options[5].

Regulatory Approvals and Compliance

Indications and Usage

Ketoprofen ER capsules are indicated for the management of the signs and symptoms of rheumatoid arthritis and osteoarthritis. They are not recommended for the treatment of acute pain due to their extended-release characteristics[1].

Safety and Side Effects

Common side effects of ketoprofen include stomach upset, dizziness, constipation, fluctuations in blood pressure, and blurred vision. Careful consideration of the potential benefits and risks is necessary before prescribing ketoprofen ER capsules[1][3].

Key Takeaways

• Growing Demand: The ketoprofen market is driven by the increasing prevalence of chronic diseases and an aging population.
• Innovative Drug Delivery: Extended-release formulations and other innovative delivery methods are enhancing the effectiveness of ketoprofen.
• Personalized Medicine: The shift towards personalized medicine is leading to more effective and safer treatments.
• Bioequivalence: Different formulations of ketoprofen ER have been shown to be bioequivalent, ensuring consistent therapeutic outcomes.
• Pricing and Discounts: Patients can benefit from discount programs to reduce the cost of ketoprofen ER capsules.
• Market Projections: The market is expected to grow significantly by 2031, driven by various trends and innovations.

FAQs

What is Ketoprofen ER used for?

Ketoprofen ER is used for the management of the signs and symptoms of rheumatoid arthritis and osteoarthritis.

How does Ketoprofen ER differ from immediate-release formulations?

Ketoprofen ER capsules are designed to release the drug at a controlled rate in the small intestine, providing sustained pain relief over a longer period compared to immediate-release formulations.

What are the common side effects of Ketoprofen ER?

Common side effects include stomach upset, dizziness, constipation, fluctuations in blood pressure, and blurred vision.

Can Ketoprofen ER be used for acute pain?

No, Ketoprofen ER is not recommended for the treatment of acute pain due to its extended-release characteristics.

How much does Ketoprofen ER cost?

The cost for ketoprofen 200 mg oral capsule, extended release, can range around $929 for a supply of 100 capsules, depending on the pharmacy and any applicable discounts.

What are the key trends driving the growth of the Ketoprofen market?

Key trends include the increasing demand for pain management solutions, advancements in drug delivery technologies, personalized medicine, sustainable manufacturing practices, and strategic partnerships and mergers.

Sources

1. Drugs.com: Ketoprofen ER Capsules: Package Insert / Prescribing Info.
2. Drugs.com: Ketoprofen Prices, Coupons, Copay Cards & Patient Assistance.
3. The Insight Partners: Ketoprofen Market Developments by 2031.
4. Scientific Research Publishing: Bioequivalence of 150 mg Extended-Release Ketoprofen.
5. Market Research Intellect: Pharmaceutical Grade Ketoprofen Market Size And Projection.