Drug Price Trends for GUAIFENESIN-PSE ER

Average Pharmacy Cost for GUAIFENESIN-PSE ER

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
GUAIFENESIN-PSE ER 600-60 MG	00536-1333-21	0.34760	EACH	2024-12-18
GUAIFENESIN-PSE ER 600-60 MG	55111-0798-36	0.34760	EACH	2024-12-18
GUAIFENESIN-PSE ER 600-60 MG	00536-1333-36	0.34760	EACH	2024-12-18
GUAIFENESIN-PSE ER 600-60 MG	55111-0798-18	0.34760	EACH	2024-12-18
GUAIFENESIN-PSE ER 600-60 MG	55111-0798-41	0.34760	EACH	2024-12-18

Market Analysis and Price Projections for Guaifenesin/Pseudoephedrine (SM GUAIFENESIN-PSE ER)

Market Overview

Guaifenesin, combined with pseudoephedrine, is a widely used medication for treating cough, nasal congestion, and other respiratory issues. The global market for this combination, particularly in its extended-release (ER) formulations like SM GUAIFENESIN-PSE ER, is driven by several key factors.

Global Market Size and Growth

The global guaifenesin market is projected to reach USD 95 million by 2027, growing at a Compound Annual Growth Rate (CAGR) of around 3.1% from 2022 to 2027[1][4].

Segmentation and Applications

Guaifenesin is available in various forms, including tablets, dissolving granules, syrup, and extended-release tablets. The extended-release formulation is particularly popular due to its convenience and efficacy in managing cough and nasal congestion over an extended period.

• Product Types: Tablets, granules, syrups, and others, with tablets leading the market share in recent years[3].
• Applications: Used as a mucolytic agent, cough suppressant, and in combination with other medications like dextromethorphan and decongestants[4].

Regional Analysis

North America

North America is the fastest-growing region in the global guaifenesin market, driven by developing medical infrastructure, growing cases of respiratory and cough-related complications, and rising health expenditure. The region accounted for a significant market share of 39.7% in 2023[3][4].

Asia Pacific

The Asia Pacific region is expected to experience the highest CAGR during the forecast period due to the rising prevalence of respiratory ailments and expanding pharmaceutical manufacturing capabilities. Countries like India and China are seeing increased demand due to rapid urbanization and higher pollution levels[3].

Drivers of the Market

Increasing Demand for Respiratory Health Products

The growing prevalence of respiratory conditions such as chronic obstructive pulmonary disease (COPD), asthma, and acute respiratory infections drives the demand for guaifenesin. According to the World Health Organization, COPD affected approximately 251 million individuals globally in 2022, highlighting the need for effective symptomatic treatments[3].

Pharmaceutical and Biotech Advancements

Innovative drug formulations and combinations of guaifenesin with other active ingredients are enhancing its market presence. Regulatory approvals for new formulations also contribute to market growth[4].

Geographical Growth

Emerging economies, particularly in India and Brazil, present significant growth opportunities due to increasing healthcare awareness and rising incidences of respiratory conditions. The Indian pharmaceutical sector is projected to grow at a CAGR of 10% during the forecast period, indicating a robust market for over-the-counter medications[3].

Challenges and Restraints

Availability of Substitutes

The global guaifenesin market faces challenges from the availability of substitute drugs, which can act as a restraint on market growth. The presence of alternative medications can pressure prices downward and affect market share[1][4].

Potential Side Effects

Guaifenesin can have side effects, which may deter some consumers and impact market growth. However, the benefits of the medication often outweigh these risks for many patients[1].

COVID-19 Impact

The COVID-19 pandemic has had a significant impact on the guaifenesin market. Initially, it caused disruptions in production and supply chains, affecting the availability of medications. However, the surge in demand for cough and cold medications during the pandemic led to growth opportunities in the market. The recovery phase saw increased production and demand, contributing to the market's growth[1][4].

Future Pricing Trends

Regulatory Changes

Negotiations and price controls, such as those implemented by the Medicare Drug Price Negotiation Program, could impact the pricing of prescription drugs, including guaifenesin/pseudoephedrine combinations[1].

Market Competition

The availability of substitutes and generic versions could pressure prices downward. Brand names like Mucinex D and Mucinex D Maximum Strength face competition from generic alternatives, which can affect pricing dynamics[2].

Demand and Supply Dynamics

Increased demand due to health crises could lead to temporary price fluctuations. However, current prices are relatively stable, with the cost for guaifenesin/pseudoephedrine (600 mg-60 mg) oral tablet, extended release, being around $11 for a supply of 18 tablets, depending on the pharmacy and use of discount cards[2].

Pricing and Cost Analysis

• Current Prices: The cost for guaifenesin/pseudoephedrine (600 mg-60 mg) oral tablet, extended release, is around $11 for a supply of 18 tablets[2].
• Discounts and Coupons: Consumers can use discount cards and copay programs to reduce the cost of the medication. For example, the Drugs.com discount card can save up to 80% or more off the cost of prescription medicines[2].

Distribution Channels

The market is segregated into retail pharmacies, hospital pharmacies, and online pharmacies. Hospital pharmacies hold the largest revenue share, indicating the significant role of healthcare institutions in the distribution of guaifenesin medications[3].

Key Takeaways

• The global guaifenesin market is projected to grow at a CAGR of around 3.1% from 2022 to 2027.
• North America is the fastest-growing region due to its developing medical infrastructure and rising health expenditure.
• The demand for guaifenesin is driven by its use in treating respiratory issues, including cough and nasal congestion.
• Regulatory changes and the availability of substitutes can impact market dynamics.
• Innovative drug formulations and growing demand in developing countries present significant growth opportunities.

Frequently Asked Questions (FAQs)

Q: What is the projected market size of the global guaifenesin market by 2027?

A: The global guaifenesin market is forecasted to reach USD 95 million by 2027[1].

Q: What are the main drivers of the guaifenesin market?

A: The main drivers include increasing demand for respiratory health products, pharmaceutical and biotech advancements, and geographical growth, particularly in North America[1][3][4].

Q: How has the COVID-19 pandemic impacted the guaifenesin market?

A: The pandemic created a surge in demand for cough and cold medications, leading to growth opportunities in the market. However, it also caused initial disruptions in production and supply chains[1][4].

Q: What are the challenges faced by the guaifenesin market?

A: The market faces challenges from the availability of substitutes, potential side effects, and stringent regulations against certain cough suppressants[1][4].

Q: What are the future pricing trends for guaifenesin/pseudoephedrine combinations?

A: Future pricing trends may be influenced by regulatory changes, market competition, and demand and supply dynamics. Current prices are around $11 for a supply of 18 tablets, but these could fluctuate based on these factors[2][5].

Highlight: Impact of COVID-19 on the Pharmaceutical Sector

"The COVID-19 pandemic has accelerated the growth of the pharmaceutical sector, including the demand for cough and cold medications. This trend is expected to continue post-pandemic, contributing to the growth of the guaifenesin market"[1].

Cited Sources

1. IndustryARC, "Guaifenesin Market Size Report, 2022-2027"[1].
2. Drugs.com, "Guaifenesin/pseudoephedrine Prices, Coupons, Copay Cards & Patient Assistance"[2].
3. Future Market Insights, "Global Expectorant Drugs Market Growth Projection 2024-2034"[3].
4. Allied Market Research, "Guaifenesin Market Size, Trends | Industry Report 2021 - 2030"[4].
5. CMS, "Medicare Drug Price Negotiation Program - CMS"[5].