Drug Price Trends for FLUORIDE

Average Pharmacy Cost for FLUORIDE

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
FLUORIDE 0.5 MG TABLET CHEW	59088-0105-73	0.06704	EACH	2024-12-18
FLUORIDE 1 MG TABLET CHEWABLE	75826-0165-20	0.06394	EACH	2024-12-18
FLUORIDE 0.25 MG TABLET CHEW	59088-0104-73	0.06748	EACH	2024-12-18
FLUORIDE 1 MG TABLET CHEWABLE	59088-0106-73	0.06394	EACH	2024-12-18
FLUORIDE 0.5 MG TABLET CHEW	75826-0164-20	0.06704	EACH	2024-12-18

Market Analysis and Price Projections for Fluoride

Introduction to Fluoride

Fluoride, a member of the minerals and electrolytes drug class, is widely used for the prevention of dental caries and in various industrial applications. The market for fluoride compounds is diverse, encompassing pharmaceuticals, dental care, water treatment, and industrial uses.

Market Segments of Fluoride

Pharmaceutical and Dental Care

In the pharmaceutical and dental care sectors, fluoride is a crucial component in products aimed at preventing dental caries and maintaining oral hygiene.

• Sodium Fluoride Market: The global sodium fluoride market, valued at USD 699.77 million in 2023, is projected to reach USD 1,155.49 million by 2032, growing at a CAGR of 5.73% during the forecast period (2024-2032). This growth is driven by increasing demand for fluoride compounds in dental care and pharmaceuticals, as well as rising awareness about oral hygiene[3].

• Fluoride Prices in Pharmaceuticals: The cost for fluoride oral tablets and solutions varies. For example, a supply of 120 chewable fluoride tablets (0.5 mg each) can cost around $13.91 to $14.68, depending on the pharmacy and any available discounts[2].

Industrial Applications

Fluoride compounds, such as calcium fluoride and anhydrous hydrogen fluoride, have significant industrial applications.

• Calcium Fluoride Market: The calcium fluoride market was valued at over USD 1.6 billion in 2024 and is expected to cross USD 4.3 billion by 2037, growing at a CAGR of more than 7.9% during the forecast period. This growth is driven by extensive applications in metallurgy, optics, and the production of hydrofluoric acid. Calcium fluoride is used as a flux in steelmaking and in the construction industry, contributing to its market expansion[1].

• Anhydrous Hydrogen Fluoride Market: The global anhydrous hydrogen fluoride market, estimated at USD 3.33 billion in 2024, is expected to grow at a CAGR of 6.0% from 2025 to 2030, reaching USD 4.70 billion by 2030. This growth is driven by the increasing demand for fluorinated products in sectors such as pharmaceuticals, agrochemicals, and electronics. Additionally, the shift towards sustainable energy solutions and eco-friendly refrigerants is boosting the market[4].

Growth Drivers

Increasing Demand in Various Industries

• The demand for fluoride compounds is increasing across multiple industries, including pharmaceuticals, dental care, and industrial sectors. For instance, the use of sodium fluoride in dental care products and calcium fluoride in metallurgy and construction materials is driving market growth[1][3].

Technological Advancements

• Research advancements, such as the use of calcium fluoride crystallization for wastewater treatment and resource recovery, are expanding the potential applications of fluoride compounds. For example, a study published by the National Center for Biotechnology Information highlighted the effectiveness of a calcium fluoride crystallization process in treating wastewater from the semiconductor industry[1].

Regulatory and Environmental Factors

• Stricter environmental regulations are driving the adoption of more eco-friendly alternatives, such as anhydrous hydrogen fluoride in the production of refrigerants with lower global warming potential. This trend supports environmental initiatives and positions AHF as a more attractive option for industries seeking sustainable practices[4].

Challenges

Market Volatility and Supply Chain Issues

• The market for fluoride compounds can be volatile due to factors such as stock shortages and fluctuations in raw material prices. These variables can affect the pricing and availability of fluoride products, making it challenging for consumers and manufacturers to predict costs and supply chains[2].

Regulatory Changes

• Changes in regulatory policies and legislation can impact the demand and pricing of fluoride compounds. For example, new policies or legislation related to environmental sustainability or public health can influence market dynamics and growth projections[5].

Regional Market Analysis

North America and APAC

• The calcium fluoride market is expected to expand significantly in North America, followed by the Asia-Pacific (APAC) region. Growing investments in infrastructural development in these regions are creating consistent revenue streams for the sector[1].

• The sodium fluoride market is also bifurcated into regions, with Asia-Pacific being the largest market and North America being the fastest-growing market[3].

Price Projections

Pharmaceutical Sector

• In the pharmaceutical sector, the prices of fluoride products are relatively stable but can vary based on the pharmacy and any available discounts. For example, the cost for a supply of 120 chewable fluoride tablets (0.5 mg each) is expected to remain in the range of $13.91 to $14.68[2].

Industrial Sector

• The prices of industrial fluoride compounds, such as calcium fluoride and anhydrous hydrogen fluoride, are influenced by market demand and supply chain factors. Given the projected growth in these markets, prices may stabilize or increase slightly over the forecast period, driven by increasing demand and potential supply constraints[1][4].

Key Takeaways

• The fluoride market is diverse, with significant growth projected in both pharmaceutical and industrial sectors.
• Increasing demand in various industries, technological advancements, and regulatory factors are driving market growth.
• Regional markets, particularly North America and APAC, are expected to see substantial expansion.
• Price stability in the pharmaceutical sector is anticipated, while industrial prices may be influenced by market dynamics and supply chain factors.

FAQs

What are the primary applications of fluoride compounds?

Fluoride compounds are used in pharmaceuticals for dental care, in industries such as metallurgy and optics, and in the production of hydrofluoric acid and other fluorinated products.

How is the calcium fluoride market expected to grow?

The calcium fluoride market is projected to grow at a CAGR of more than 7.9% from 2025 to 2037, reaching USD 4.3 billion by 2037.

What drives the demand for sodium fluoride?

The demand for sodium fluoride is driven by increasing awareness of oral hygiene and the importance of fluoride in dental health maintenance, as well as its use in pharmaceuticals and water treatment.

How does anhydrous hydrogen fluoride contribute to sustainable practices?

Anhydrous hydrogen fluoride is used in the production of refrigerants with lower global warming potential, supporting environmental initiatives and sustainable practices.

What are the potential challenges in the fluoride market?

The market can face challenges such as stock shortages, fluctuations in raw material prices, and changes in regulatory policies, which can affect pricing and availability.

Sources

1. Research Nester: Calcium Fluoride Market Size & Share | Growth Forecasts 2037
2. Drugs.com: Fluoride Prices, Coupons, Copay Cards & Patient Assistance
3. Straits Research: Sodium Fluoride Market Size, Growth & Share | Forecast-2032
4. Grand View Research: Anhydrous Hydrogen Fluoride Market | Industry Report, 2030
5. PubMed: National trends in prescription drug expenditures and projections for 2024