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Last Updated: February 10, 2025

Drug Price Trends for DOTTI


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Drug Price Trends for DOTTI

Average Pharmacy Cost for DOTTI

These are average pharmacy acquisition costs (net of discounts) from a US national survey
Drug Name NDC Price/Unit ($) Unit Date
DOTTI 0.025 MG PATCH 65162-0989-08 5.92120 EACH 2025-01-22
DOTTI 0.0375 MG PATCH 65162-0992-08 6.32083 EACH 2025-01-22
DOTTI 0.05 MG PATCH 65162-0993-04 5.92804 EACH 2025-01-22
DOTTI 0.0375 MG PATCH 65162-0992-04 6.32083 EACH 2025-01-22
DOTTI 0.1 MG PATCH 65162-0997-08 6.19621 EACH 2025-01-22
>Drug Name >NDC >Price/Unit ($) >Unit >Date

Market Analysis and Price Projections for Dotti

Introduction to Dotti

Dotti, an estradiol patch, is a widely used medication for managing menopause symptoms such as hot flashes and vaginal dryness. It belongs to the estrogens drug class and is available in various strengths and forms.

Current Market Trends

Rising Costs of Menopause Medications

Over the last decade, the list prices for menopause medications, including Dotti, have increased significantly. There has been a 58% rise in list prices for these medications, making them less affordable for many patients[1].

Insurance Coverage and Restrictions

Insurance coverage for menopause medications is uneven, with some drugs facing tough restrictions like prior authorization and step therapy. This variability in coverage can significantly impact the out-of-pocket costs for patients. For instance, while some medications remain affordable with insurance, others can cost patients around $100 out of pocket per prescription[1].

Pricing of Dotti

Current Pricing

The cost of Dotti varies based on the dosage and the pharmacy. For example, a 30-day supply of Dotti transdermal film (0.025 mg/24 hours, twice weekly) can range from $40.71 to $49.90, depending on the dosage and the pharmacy[5].

Dosage Quantity Per Unit Price
0.025 mg/24 hrs 8 films $5.09 $40.71
0.0375 mg/24 hrs 8 films $4.74 $37.88
0.05 mg/24 hrs 8 films $6.23 $49.86
0.075 mg/24 hrs 8 films $6.24 $49.90
0.1 mg/24 hrs 8 films $5.27 $42.17

Impact of Generic Options

The introduction of new generic options has led to a slight drop in list prices for menopause medications since September 2020. This trend is expected to continue, potentially stabilizing or reducing the costs of medications like Dotti[1].

Future Price Projections

Regulatory Changes

The Inflation Reduction Act of 2022 includes provisions that could impact the pricing and affordability of prescription drugs, including those used for menopause. Key provisions include capping Medicare Part D out-of-pocket drug spending to $2,000 annually starting in 2025 and requiring pharmaceutical manufacturers to pay rebates to Medicare if their prices rise faster than inflation. These changes are expected to reduce aggregate drug costs and plateau out-of-pocket spending in the next decade[2].

Market Forecast

While the overall trend in retail prescription drug spending is expected to moderate in the next decade, out-of-pocket spending is projected to decline. By 2030, total out-of-pocket spending on retail prescription drugs is expected to be $48.1 billion, which is 18.5% lower than previously projected. This decline could benefit patients using medications like Dotti[2].

Utilization and Coverage

Increased Utilization

Legislative changes, such as California Assembly Bill 2467, aim to increase coverage for menopause medications. If enacted, such bills could lead to increased utilization of drugs like Dotti and ospemifene, as more patients would have access to these treatments without significant financial barriers[3].

Insurance Coverage Variability

Despite these efforts, insurance coverage remains variable. Some menopause medications have better coverage than others, leaving patients at the mercy of their insurance plans. This variability can affect the affordability and accessibility of Dotti for many women[1].

Consumer and Market Insights

Patient Burden

The rising costs of menopause medications, including Dotti, have significant implications for patients. On average, women taking these medications spend $14.33 out of pocket per prescription, though this number can be much higher for medications with poor coverage[1].

Market Dynamics

The market for menopause medications is influenced by the availability of generic options, regulatory changes, and insurance coverage policies. As new generic options become available, they can drive down the prices of brand-name medications, making them more affordable for patients.

Key Takeaways

  • Price Increases: List prices for menopause medications, including Dotti, have risen by 58% over the last decade.
  • Insurance Variability: Insurance coverage for menopause medications is uneven, leading to significant out-of-pocket costs for some patients.
  • Generic Options: The introduction of generic options has led to a slight drop in list prices since 2020.
  • Regulatory Impact: The Inflation Reduction Act is expected to reduce aggregate drug costs and plateau out-of-pocket spending.
  • Utilization and Coverage: Legislative changes could increase the utilization of menopause medications by improving coverage.

FAQs

What is Dotti used for?

Dotti is used to manage menopause symptoms such as hot flashes and vaginal dryness. It is an estradiol patch that helps maintain hormone levels.

How much does Dotti cost?

The cost of Dotti varies based on the dosage and pharmacy, ranging from $37.88 to $49.90 for an 8-film supply.

Is Dotti covered by insurance?

Insurance coverage for Dotti can be variable. Some insurance plans cover it well, while others may have restrictions or higher out-of-pocket costs.

How have regulatory changes affected Dotti pricing?

Regulatory changes, such as the Inflation Reduction Act, are expected to reduce aggregate drug costs and plateau out-of-pocket spending, potentially making Dotti more affordable.

What is the impact of generic options on Dotti pricing?

The introduction of new generic options has led to a slight drop in list prices for menopause medications, including Dotti, since September 2020.

Sources

  1. GoodRx, "Menopause Medication Costs Have Surged 58% in the Last Decade", October 22, 2024.
  2. Health System Tracker, "What are the recent and forecasted trends in prescription drug spending?", September 15, 2023.
  3. California Health Benefits Review Program, "Analysis of California Assembly Bill 2467 Menopause", April 16, 2024.
  4. Atrium24, "Dotti".
  5. Drugs.com, "Dotti Prices, Coupons, Copay Cards & Patient Assistance".

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