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Last Updated: January 21, 2025

Drug Price Trends for DESOGESTR-ETH ESTRAD ETH ESTRA


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Drug Price Trends for DESOGESTR-ETH ESTRAD ETH ESTRA

Average Pharmacy Cost for DESOGESTR-ETH ESTRAD ETH ESTRA

These are average pharmacy acquisition costs (net of discounts) from a US national survey
Drug Name NDC Price/Unit ($) Unit Date
DESOGESTR-ETH ESTRAD ETH ESTRA 00378-7296-53 0.16805 EACH 2024-12-18
DESOGESTR-ETH ESTRAD ETH ESTRA 00378-7296-53 0.15631 EACH 2024-11-20
DESOGESTR-ETH ESTRAD ETH ESTRA 00378-7296-53 0.20807 EACH 2024-10-23
DESOGESTR-ETH ESTRAD ETH ESTRA 00378-7296-53 0.19599 EACH 2024-09-18
DESOGESTR-ETH ESTRAD ETH ESTRA 00378-7296-53 0.19983 EACH 2024-08-21
DESOGESTR-ETH ESTRAD ETH ESTRA 00378-7296-53 0.15764 EACH 2024-07-17
>Drug Name >NDC >Price/Unit ($) >Unit >Date

Market Analysis and Price Projections for Desogestrel and Ethinyl Estradiol

Introduction

Desogestrel and ethinyl estradiol, a combination oral contraceptive, is widely used for birth control, as well as for treating conditions such as abnormal uterine bleeding and endometriosis. This analysis will delve into the market dynamics, pricing, and future projections for this medication.

Market Overview

The global market for desogestrel and ethinyl estradiol tablets is robust and growing, driven by increasing demand for effective contraceptive methods and treatments for gynecological conditions.

Key Players

Major pharmaceutical companies such as Cipla, Bayer, and Merck are prominent players in the global desogestrel and ethinyl estradiol tablets market. These companies have a significant market share and are involved in various strategies including new product launches, partnerships, and mergers or acquisitions to maintain their market position[3].

Market Segmentation

The market is segmented by region, type, and application. Regions include North America, Europe, Asia Pacific, and Latin America, each with varying market sizes and growth rates. The product types include different dosages and formulations, such as biphasic and monophasic tablets. Applications include birth control, abnormal uterine bleeding, and endometriosis[3].

Pricing and Cost Analysis

The cost of desogestrel and ethinyl estradiol tablets can vary based on the pharmacy, location, and the specific formulation.

Current Pricing

  • The cost for a supply of 84 biphasic oral tablets can range from approximately $36.38 to $56.47, depending on the dosage and pharmacy[2].
  • For example, a 0.15 mg-0.03 mg desogestrel and ethinyl estradiol oral tablet can cost around $36.38 for 84 tablets, while a different formulation might cost around $56.47 for the same quantity[2].

Discount Programs and Patient Assistance

Several discount programs, coupons, and copay cards are available to reduce the cost of this medication. However, there are no specific patient assistance programs (PAPs) directly associated with desogestrel and ethinyl estradiol. Patients can use general discount cards accepted at most U.S. pharmacies to save up to 80% on their prescriptions[2].

Market Trends and Projections

The global desogestrel and ethinyl estradiol tablets market is expected to grow significantly over the forecast period of 2023-2029.

Regional Growth

  • North America, Europe, and the Asia Pacific are expected to be key regions driving market growth. The Asia Pacific region, in particular, is anticipated to show high growth rates due to increasing awareness and demand for contraceptive methods[3].

Sales and Revenue

  • The market is projected to see an increase in sales and revenue, driven by the growing need for effective contraceptive solutions and treatments for gynecological conditions. The global sales and revenue are expected to rise steadily over the forecast period[3].

Pharmacokinetics and Clinical Significance

Understanding the pharmacokinetics of desogestrel and ethinyl estradiol is crucial for its effective use.

Absorption and Bioavailability

  • Desogestrel is rapidly absorbed and converted into its active metabolite, etonogestrel, with a relative bioavailability of approximately 100%. Ethinyl estradiol is also rapidly absorbed, with a relative bioavailability of around 93% for the combination tablet[1][4].

Distribution and Metabolism

  • Etonogestrel is 99% protein-bound, primarily to sex hormone-binding globulin (SHBG), while ethinyl estradiol is approximately 98.3% bound, mainly to plasma albumin. Ethinyl estradiol induces SHBG synthesis, which can affect serum levels of free testosterone[1][4].

Special Populations

The pharmacokinetics of desogestrel and ethinyl estradiol can vary in special populations.

Hepatic and Renal Insufficiency

  • There are no formal studies on the effect of hepatic or renal insufficiency on the disposition of desogestrel and ethinyl estradiol. Therefore, caution is advised when prescribing this medication to patients with these conditions[4].

Conclusion

The market for desogestrel and ethinyl estradiol tablets is dynamic and growing, driven by increasing demand and the presence of major pharmaceutical players. Here are some key takeaways:

  • Market Growth: The global market is expected to grow significantly over the forecast period of 2023-2029, driven by regions such as the Asia Pacific.
  • Pricing: The cost of the medication varies, with discounts and patient assistance programs available to reduce costs.
  • Pharmacokinetics: The medication is rapidly absorbed and has high bioavailability, with significant protein binding.
  • Special Populations: Caution is advised when prescribing to patients with hepatic or renal insufficiency due to lack of formal studies.

Key Takeaways

  • Increasing Demand: Growing need for effective contraceptive methods and treatments for gynecological conditions.
  • Major Players: Companies like Cipla, Bayer, and Merck are key players in the market.
  • Regional Growth: Asia Pacific region expected to show high growth rates.
  • Pricing Variability: Costs vary based on pharmacy and formulation.
  • Pharmacokinetics: Rapid absorption and high bioavailability of both desogestrel and ethinyl estradiol.
  • Special Populations: Caution advised for patients with hepatic or renal insufficiency.

FAQs

Q: What are the common uses of desogestrel and ethinyl estradiol tablets? A: Desogestrel and ethinyl estradiol tablets are commonly used for birth control, abnormal uterine bleeding, and endometriosis.

Q: Which companies are major players in the desogestrel and ethinyl estradiol market? A: Major players include Cipla, Bayer, and Merck.

Q: How much do desogestrel and ethinyl estradiol tablets typically cost? A: The cost can range from approximately $36.38 to $56.47 for a supply of 84 tablets, depending on the dosage and pharmacy.

Q: Are there any discount programs available for desogestrel and ethinyl estradiol? A: Yes, various discount programs, coupons, and copay cards are available to reduce the cost of the medication.

Q: How are desogestrel and ethinyl estradiol absorbed and metabolized in the body? A: Desogestrel is rapidly absorbed and converted into etonogestrel, while ethinyl estradiol is also rapidly absorbed. Both are highly protein-bound and have significant metabolic pathways[1][4].

Sources

  1. DailyMed: Desogestrel and Ethinyl Estradiol Tablets, USP and Ethinyl Estradiol Tablets, USP[1].
  2. Drugs.com: Desogestrel/ethinyl estradiol Prices, Coupons, Copay Cards & Patient Assistance[2].
  3. OpenPR: Global Desogestrel and Ethinyl Estradiol Tablets Market[3].
  4. DailyMed: VIORELE- desogestrel and ethinyl estradiol and ethinyl estradiol tablets, USP[4].

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