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Drug Price Trends for CODEINE-GUAIFEN
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Average Pharmacy Cost for CODEINE-GUAIFEN
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| CODEINE-GUAIFEN 10-100 MG/5 ML | 58657-0500-16 | 0.03283 | ML | 2024-12-18 |
| CODEINE-GUAIFEN 10-100 MG/5 ML | 69367-0272-16 | 0.03283 | ML | 2024-12-18 |
| CODEINE-GUAIFEN 10-100 MG/5 ML | 70752-0180-06 | 0.05334 | ML | 2024-12-18 |
| CODEINE-GUAIFEN 10-100 MG/5 ML | 69367-0272-04 | 0.05334 | ML | 2024-12-18 |
| CODEINE-GUAIFEN 10-100 MG/5 ML | 70752-0180-12 | 0.03283 | ML | 2024-12-18 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Market Analysis and Price Projections for Codeine-Guaifenesin
Introduction
Codeine-guaifenesin is a combination medication commonly used to treat cough and cold symptoms. The market for this drug has undergone significant changes in recent years, driven by regulatory actions, safety concerns, and market dynamics.
Regulatory Impact
The U.S. Food and Drug Administration (FDA) has played a crucial role in shaping the market for codeine-guaifenesin. In April 2017, the FDA issued a safety communication announcing a contraindication against the use of codeine in children aged 0 to 11 years. This was followed by another communication in January 2018, extending the contraindication to children and adolescents aged 0 to 17 years for both codeine and hydrocodone cough and cold medications[1][4].
These regulatory actions led to a significant decline in prescriptions. Between 2014 and 2019, prescriptions for codeine cough and cold medications dropped by 90.1%, and those for hydrocodone cough and cold medications decreased by 75.7%[1].
Market Size and Growth
Despite the decline in prescriptions due to regulatory restrictions, the overall demand for cough and cold medications remains robust. The global guaifenesin market, which includes guaifenesin-codeine combinations, is forecasted to grow at a Compound Annual Growth Rate (CAGR) of around 3.1% from 2022 to 2027, reaching a market size of USD 95 million by 2027[3].
Price Dynamics
The cost of codeine-guaifenesin can vary depending on the pharmacy and the use of discount cards or coupons. Here are some current price points:
- The average cost for a 118 mL bottle of codeine-guaifenesin oral syrup is around $13 to $15, depending on the pharmacy[5][2].
- Using discount cards or coupons can reduce the cost significantly. For example, the WebMDRx coupon can lower the price to around $9 to $19, depending on the pharmacy[2].
Regional Market Analysis
North America is the fastest-growing region in the global guaifenesin market, driven by developing medical infrastructure, increasing cases of respiratory and cough-related complications, and rising health expenditure. This region accounted for the largest pharmaceutical sales in 2020, with 49% of global sales[3].
Drivers of Market Growth
Several factors are driving the growth of the guaifenesin market, including:
- Increasing Number of Cough Cases: The rise in whooping cough or pertussis cases is boosting the demand for guaifenesin-based medications[3].
- Advancements in Medical and Pharmaceutical Sectors: Innovative drug technologies and the development of new pharmaceutical medications are contributing to market growth[3].
- COVID-19 Impact: The pandemic led to increased demand for cough and cold medications, particularly during the recovery phase, which has driven growth opportunities in the guaifenesin market[3].
Challenges
Despite the growth drivers, the market faces several challenges:
- Availability of Substitutes: The presence of alternative medications can impact the demand for guaifenesin-codeine combinations[3].
- Potential Side Effects: Safety concerns, such as respiratory depression in children, have led to regulatory restrictions and may affect consumer confidence[1][4].
Price Projections
Given the current market trends and regulatory environment, here are some price projections:
- Short-Term: Prices are likely to remain stable or experience slight fluctuations due to the availability of discount cards and coupons. However, the overall cost may not decrease significantly due to the fixed production costs and regulatory compliance expenses.
- Long-Term: As the market continues to grow, driven by increasing demand for cough and cold medications, prices might see a slight increase. However, this will be balanced by the competitive nature of the pharmaceutical market and the availability of generic alternatives.
Key Takeaways
- Regulatory actions have significantly reduced prescriptions for codeine-guaifenesin in children and adolescents.
- The global guaifenesin market is expected to grow, driven by increasing demand for cough and cold medications.
- Prices for codeine-guaifenesin are relatively stable, with opportunities for savings through discount cards and coupons.
- North America is a key region driving market growth due to its robust healthcare infrastructure and high demand for pharmaceuticals.
Frequently Asked Questions (FAQs)
Q: What led to the decline in prescriptions for codeine-guaifenesin? A: The decline was primarily due to FDA safety communications in 2017 and 2018, which restricted the use of codeine in children and adolescents due to safety concerns[1][4].
Q: How is the global guaifenesin market expected to grow? A: The global guaifenesin market is forecasted to grow at a CAGR of around 3.1% from 2022 to 2027, reaching a market size of USD 95 million by 2027[3].
Q: What are the current prices for codeine-guaifenesin? A: The average cost for a 118 mL bottle of codeine-guaifenesin oral syrup is around $13 to $15, with potential savings through discount cards and coupons[5][2].
Q: Which region is driving the growth of the guaifenesin market? A: North America is the fastest-growing region, driven by developing medical infrastructure and increasing cases of respiratory and cough-related complications[3].
Q: What challenges does the guaifenesin market face? A: The market faces challenges such as the availability of substitutes and potential side effects, which can impact demand and consumer confidence[3].
Cited Sources:
- JAMA Network Open: "Prescriptions for Codeine or Hydrocodone Cough and Cold Medications Declined Substantially After US Food and Drug Administration Safety Communications."
- WebMDRx: "Codeine Guaifenesin Prices, Coupons & Savings Tips."
- IndustryARC: "Guaifenesin Market Size Report, 2022-2027."
- FDA: "FDA restricts use of prescription codeine pain and cough medicines and tramadol pain medicines."
- Drugs.com: "Codeine/guaifenesin Prices, Coupons, Copay Cards & Patient Assistance."
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