Last Updated: August 9, 2026

CLINICAL TRIALS PROFILE FOR TROSPIUM CHLORIDE; XANOMELINE TARTRATE


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All Clinical Trials for trospium chloride; xanomeline tartrate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT02831231 ↗ Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium Completed Karuna Pharmaceuticals Phase 1 2016-09-07 This study is intended to determine whether the addition of trospium chloride to xanomeline tartrate will ameliorate the peripheral cholinergic side effects that have been previously experienced with xanomeline tartrate when administered alone.
NCT02831231 ↗ Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium Completed Karuna Therapeutics Phase 1 2016-09-07 This study is intended to determine whether the addition of trospium chloride to xanomeline tartrate will ameliorate the peripheral cholinergic side effects that have been previously experienced with xanomeline tartrate when administered alone.
NCT06937229 ↗ A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3) NOT_YET_RECRUITING Bristol-Myers Squibb PHASE3 2025-11-21 The purpose of this study is to evaluate the long-term efficacy and safety of combined formulation of xanomeline tartrate/trospium chloride in an immediate release (IR) capsule (KarXT) and xanomeline enteric capsules (KarX-EC) in participants with agitation associated with Alzheimer's Disease who completed the parent studies CN012-0023 or CN012-0024.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for trospium chloride; xanomeline tartrate

Condition Name

Condition Name for trospium chloride; xanomeline tartrate
Intervention Trials
Agitation 1
Alzheimer Disease 1
Cognitive Impairment 1
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Condition MeSH

Condition MeSH for trospium chloride; xanomeline tartrate
Intervention Trials
Schizophrenia 2
Psychotic Disorders 1
Cognitive Dysfunction 1
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Clinical Trial Locations for trospium chloride; xanomeline tartrate

Trials by Country

Trials by Country for trospium chloride; xanomeline tartrate
Location Trials
United States 19
India 6
Czechia 5
Brazil 5
Japan 5
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Trials by US State

Trials by US State for trospium chloride; xanomeline tartrate
Location Trials
Ohio 2
Arizona 1
Washington 1
Vermont 1
Utah 1
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Clinical Trial Progress for trospium chloride; xanomeline tartrate

Clinical Trial Phase

Clinical Trial Phase for trospium chloride; xanomeline tartrate
Clinical Trial Phase Trials
PHASE3 2
Phase 1 1
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Clinical Trial Status

Clinical Trial Status for trospium chloride; xanomeline tartrate
Clinical Trial Phase Trials
NOT_YET_RECRUITING 2
Completed 1
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Clinical Trial Sponsors for trospium chloride; xanomeline tartrate

Sponsor Name

Sponsor Name for trospium chloride; xanomeline tartrate
Sponsor Trials
Bristol-Myers Squibb 2
Karuna Pharmaceuticals 1
Karuna Therapeutics 1
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Sponsor Type

Sponsor Type for trospium chloride; xanomeline tartrate
Sponsor Trials
Industry 4
OTHER 2
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