Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium
Completed
Karuna Pharmaceuticals
Phase 1
2016-09-07
This study is intended to determine whether the addition of trospium chloride to xanomeline
tartrate will ameliorate the peripheral cholinergic side effects that have been previously
experienced with xanomeline tartrate when administered alone.
Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium
Completed
Karuna Therapeutics
Phase 1
2016-09-07
This study is intended to determine whether the addition of trospium chloride to xanomeline
tartrate will ameliorate the peripheral cholinergic side effects that have been previously
experienced with xanomeline tartrate when administered alone.
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
NOT_YET_RECRUITING
Bristol-Myers Squibb
PHASE3
2025-11-21
The purpose of this study is to evaluate the long-term efficacy and safety of combined formulation of xanomeline tartrate/trospium chloride in an immediate release (IR) capsule (KarXT) and xanomeline enteric capsules (KarX-EC) in participants with agitation associated with Alzheimer's Disease who completed the parent studies CN012-0023 or CN012-0024.
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