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Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
Express Scripts
Julphar
UBS
Argus Health
Accenture
Citi
Healthtrust
Merck

Generated: July 22, 2018

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CLINICAL TRIALS PROFILE FOR TRIMETHOPRIM HYDROCHLORIDE

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Clinical Trials for trimethoprim hydrochloride

Trial ID Title Status Sponsor Phase Summary
NCT00000640 A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS Completed Glaxo Wellcome Phase 3 To evaluate the effectiveness of two oral treatments for mild to moderate Pneumocystis carinii pneumonia (PCP): dapsone/trimethoprim or clindamycin/primaquine as compared to a standard treatment program of sulfamethoxazole/trimethoprim (SMX/TMP) to assess the tolerance of these two alternative treatments as compared to the standard treatment of SMX/TMP. Per 09/09/92 amendment, to assess the efficacy and tolerance of these two alternative treatments in patients who are intolerant to SMX/TMP. The type of treatment being studied has the advantages of wide applicability throughout the world (including developing countries) and low cost. An oral treatment is more accessible to patients than drugs given by injection or by inhalation.
NCT00000640 A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS Completed Jacobus Pharmaceutical Phase 3 To evaluate the effectiveness of two oral treatments for mild to moderate Pneumocystis carinii pneumonia (PCP): dapsone/trimethoprim or clindamycin/primaquine as compared to a standard treatment program of sulfamethoxazole/trimethoprim (SMX/TMP) to assess the tolerance of these two alternative treatments as compared to the standard treatment of SMX/TMP. Per 09/09/92 amendment, to assess the efficacy and tolerance of these two alternative treatments in patients who are intolerant to SMX/TMP. The type of treatment being studied has the advantages of wide applicability throughout the world (including developing countries) and low cost. An oral treatment is more accessible to patients than drugs given by injection or by inhalation.
NCT00000640 A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 3 To evaluate the effectiveness of two oral treatments for mild to moderate Pneumocystis carinii pneumonia (PCP): dapsone/trimethoprim or clindamycin/primaquine as compared to a standard treatment program of sulfamethoxazole/trimethoprim (SMX/TMP) to assess the tolerance of these two alternative treatments as compared to the standard treatment of SMX/TMP. Per 09/09/92 amendment, to assess the efficacy and tolerance of these two alternative treatments in patients who are intolerant to SMX/TMP. The type of treatment being studied has the advantages of wide applicability throughout the world (including developing countries) and low cost. An oral treatment is more accessible to patients than drugs given by injection or by inhalation.
NCT00000655 A Randomized, Double-Blind Study of 566C80 Versus Septra (Sulfamethoxazole/Trimethoprim) for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients Completed Glaxo Wellcome Phase 2 To evaluate the effectiveness of atovaquone (566C80) compared to a standard antipneumocystis agent, (SMX/TMP), for the treatment of mild to moderate Pneumocystis carinii pneumonia (PCP) in AIDS patients. To compare the safety of short-term (21 days) treatment with 566C80 and SMX/TMP in AIDS patients with an acute episode of PCP. Standard therapies for acute treatment of PCP involve either SMX/TMP or pentamidine isetionate. Although both treatments are equally effective, side effects prevent completion of therapy in 11-55 percent of patients.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for trimethoprim hydrochloride

Condition Name

Condition Name for trimethoprim hydrochloride
Intervention Trials
HIV Infections 36
Pneumonia, Pneumocystis Carinii 27
Urinary Tract Infection 8
Malaria 6
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Condition MeSH

Condition MeSH for trimethoprim hydrochloride
Intervention Trials
HIV Infections 38
Pneumonia 35
Pneumonia, Pneumocystis 29
Infection 27
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Clinical Trial Locations for trimethoprim hydrochloride

Trials by Country

Trials by Country for trimethoprim hydrochloride
Location Trials
United States 385
Canada 12
Ukraine 8
Netherlands 8
Uganda 6
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Trials by US State

Trials by US State for trimethoprim hydrochloride
Location Trials
California 30
New York 25
Illinois 23
Texas 19
Ohio 19
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Clinical Trial Progress for trimethoprim hydrochloride

Clinical Trial Phase

Clinical Trial Phase for trimethoprim hydrochloride
Clinical Trial Phase Trials
Phase 4 22
Phase 3 37
Phase 2/Phase 3 4
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Clinical Trial Status

Clinical Trial Status for trimethoprim hydrochloride
Clinical Trial Phase Trials
Completed 85
Recruiting 23
Terminated 10
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Clinical Trial Sponsors for trimethoprim hydrochloride

Sponsor Name

Sponsor Name for trimethoprim hydrochloride
Sponsor Trials
National Institute of Allergy and Infectious Diseases (NIAID) 28
Glaxo Wellcome 8
M.D. Anderson Cancer Center 8
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Sponsor Type

Sponsor Type for trimethoprim hydrochloride
Sponsor Trials
Other 149
NIH 50
Industry 45
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Serving hundreds of leading biopharmaceutical companies globally:

UBS
Moodys
Dow
Cantor Fitzgerald
AstraZeneca
Chubb
Cerilliant
Covington
QuintilesIMS

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