Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe
Completed
Elan Pharmaceuticals
Phase 3
2002-06-01
This study is being conducted to compare the impact of somnolence (sleepiness) on cognition
(awareness) as well as the safety and effectiveness of tizanidine hydrochloride capsules
versus Zanaflex® (tizanidine hydrochloride tablets) taken while in the fed state (just after
a meal) and in the fasted state (before a meal) in patients with moderate to severe
spasticity.
Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity
Completed
Allergan
Phase 4
2002-01-01
The study seeks to compare the effectiveness of three preparations of BOTOX-A® in treating
muscle tightness and spasms in the feet and ankles of people with stroke.
Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity
Completed
The University of Texas Health Science Center, Houston
Phase 4
2002-01-01
The study seeks to compare the effectiveness of three preparations of BOTOX-A® in treating
muscle tightness and spasms in the feet and ankles of people with stroke.
Hypothesis A single subanesthetic dose of propofol will result in improved pain and quality
of life for the next 30 days in persons with chronic daily headache (CDH)
Specific objectives To measure the effect of a single infusion of propofol at 40 mcg / kg /
minute over 60 mins on headache-related quality of life (measured by the Headache Disability
Index) and on headache severity (measured by the Headache Index) in subjects with chronic
daily headache over 30 days45-47
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