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Last Updated: May 2, 2024

CLINICAL TRIALS PROFILE FOR SULFAPYRIDINE

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All Clinical Trials for sulfapyridine

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT05580861 ↗	Sulfasalazine in AML Treated by Intensive Chemotherapy: Elderly Patients-first Line Treatment	Not yet recruiting	Assistance Publique - Hôpitaux de Paris	Phase 1/Phase 2	2022-10-01	Acute myeloid leukemia (AML) is a heterogeneous clonal myeloid neoplasm where abnormal proliferation and impaired differentiation of hematopoietic stem and myeloid progenitor cells impedes normal hematopoiesis. Sulfasalazine (SSZ) is a broadly available, well tolerated anti-inflammatory medicine approved for the treatment of ulcerative colitis and rheumatoid arthritis. Intact SSZ, but not its metabolites 5-aminosalicylic acid and sulfapyridine, competitively inhibits xCT.21 SSZ is thus an ideal candidate for drug repurposing in AML.The purpose of this phase I study is to evaluate the safety and feasibility of such strategy, provide preliminary signals of efficacy, and identify potential biomarkers
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for sulfapyridine

Condition Name

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Condition Name for sulfapyridine
Intervention	Trials
Acute Myeloid Leukemia	1
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Condition MeSH

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Condition MeSH for sulfapyridine
Intervention	Trials
Leukemia, Myeloid	1
Leukemia	1
Leukemia, Myeloid, Acute	1
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Clinical Trial Progress for sulfapyridine

Clinical Trial Phase

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Clinical Trial Phase for sulfapyridine
Clinical Trial Phase	Trials
Phase 1/Phase 2	1
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Clinical Trial Status

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Clinical Trial Status for sulfapyridine
Clinical Trial Phase	Trials
Not yet recruiting	1
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Clinical Trial Sponsors for sulfapyridine

Sponsor Name

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Sponsor Name for sulfapyridine
Sponsor	Trials
Assistance Publique - Hôpitaux de Paris	1
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Sponsor Type

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Sponsor Type for sulfapyridine
Sponsor	Trials
Other	1
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