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Last Updated: May 15, 2024

CLINICAL TRIALS PROFILE FOR SPARSENTAN

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All Clinical Trials for sparsentan

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT01613118 ↗	Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis	Active, not recruiting	Retrophin, Inc.	Phase 2	2014-03-01	This study will investigate whether RE-021 (Sparsentan), a selective dual-acting receptor antagonist with affinity for endothelin (A type) and angiotensin II receptors (Type 1), is safe and effective in treating patients with focal segmental glomerulosclerosis (FSGS).
NCT01613118 ↗	Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis	Active, not recruiting	Travere Therapeutics, Inc.	Phase 2	2014-03-01	This study will investigate whether RE-021 (Sparsentan), a selective dual-acting receptor antagonist with affinity for endothelin (A type) and angiotensin II receptors (Type 1), is safe and effective in treating patients with focal segmental glomerulosclerosis (FSGS).
NCT03493685 ↗	Study of Sparsentan in Patients With Primary Focal Segmental Glomerulosclerosis (FSGS)	Active, not recruiting	Retrophin, Inc.	Phase 3	2018-03-29	To determine the long-term nephroprotective potential of treatment with sparsentan as compared to an angiotensin receptor blocker in patients with primary and genetic focal segmental glomerulosclerosis (FSGS).
NCT03493685 ↗	Study of Sparsentan in Patients With Primary Focal Segmental Glomerulosclerosis (FSGS)	Active, not recruiting	Travere Therapeutics, Inc.	Phase 3	2018-03-29	To determine the long-term nephroprotective potential of treatment with sparsentan as compared to an angiotensin receptor blocker in patients with primary and genetic focal segmental glomerulosclerosis (FSGS).
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for sparsentan

Condition Name

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Condition Name for sparsentan
Intervention	Trials
Immunoglobulin A Nephropathy	4
Focal Segmental Glomerulosclerosis	3
Kidney Diseases	2
ANCA Associated Vasculitis	1
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Condition MeSH

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Condition MeSH for sparsentan
Intervention	Trials
Glomerulonephritis, IGA	4
Kidney Diseases	3
Glomerulosclerosis, Focal Segmental	3
Vasculitis	2
[disabled in preview]	0
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Clinical Trial Locations for sparsentan

Trials by Country

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Trials by Country for sparsentan
Location	Trials
United States	82
United Kingdom	23
Australia	10
Germany	9
Spain	8
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Trials by US State

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Trials by US State for sparsentan
Location	Trials
Florida	4
New York	4
Colorado	4
Washington	3
New Jersey	3
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Clinical Trial Progress for sparsentan

Clinical Trial Phase

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Clinical Trial Phase for sparsentan
Clinical Trial Phase	Trials
Phase 3	2
Phase 2	5
Phase 1	1
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Clinical Trial Status

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Clinical Trial Status for sparsentan
Clinical Trial Phase	Trials
Recruiting	3
Active, not recruiting	3
Completed	1
[disabled in preview]	1
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Clinical Trial Sponsors for sparsentan

Sponsor Name

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Sponsor Name for sparsentan
Sponsor	Trials
Travere Therapeutics, Inc.	8
Retrophin, Inc.	3
University of Leicester	1
[disabled in preview]	1
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Sponsor Type

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Sponsor Type for sparsentan
Sponsor	Trials
Industry	11
Other	2
[disabled in preview]	0
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