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Last Updated: March 29, 2024

CLINICAL TRIALS PROFILE FOR SACUBITRIL; VALSARTAN


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All Clinical Trials for sacubitril; valsartan

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01920711 ↗ Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction Completed Novartis Pharmaceuticals Phase 3 2014-07-18 The purpose of this study was to evaluate the effect of LCZ696 compared to valsartan in the reduction of cardiovascular death and heart failure(HF) hospitalizations in patients with HF with preserved ejection fraction.
NCT02554890 ↗ Comparison of Sacubitril/Valsartan Versus Enalapril on Effect on NT-proBNP in Patients Stabilized From an Acute Heart Failure Episode. Completed Novartis Pharmaceuticals Phase 4 2016-04-29 The purpose of this study was to assess the effect of in-hospital initiation of sacubitril/valsartan (LCZ696) vs. enalapril on time averaged proportional change in NT-proBNP in patients who have been stabilized following hospitalization for acute decompensated heart failure (ADHF) and reduced ejection fraction (left ventricular ejection fraction (LVEF) ≤ 40%).
NCT02636283 ↗ Use of Entresto Sacubitril/Valsartan for the Treatment of Peripheral Arterial Disease Terminated American Heart Association Phase 2 2017-12-31 This study proposes the use of Entresto (sacubitril/valsartan) to test the effects on pain free walking duration on patients with peripheral arterial disease, a condition caused by decreased blood flow to the muscles in the legs.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for sacubitril; valsartan

Condition Name

Condition Name for sacubitril; valsartan
Intervention Trials
Heart Failure 30
Hypertension 8
Heart Failure With Preserved Ejection Fraction 7
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Condition MeSH

Condition MeSH for sacubitril; valsartan
Intervention Trials
Heart Failure 57
Hypertension 7
Myocardial Infarction 6
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Clinical Trial Locations for sacubitril; valsartan

Trials by Country

Trials by Country for sacubitril; valsartan
Location Trials
United States 249
Spain 45
Italy 42
Japan 36
United Kingdom 35
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Trials by US State

Trials by US State for sacubitril; valsartan
Location Trials
Massachusetts 10
California 10
Virginia 9
Tennessee 9
Pennsylvania 9
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Clinical Trial Progress for sacubitril; valsartan

Clinical Trial Phase

Clinical Trial Phase for sacubitril; valsartan
Clinical Trial Phase Trials
Phase 4 39
Phase 3 15
Phase 2/Phase 3 2
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Clinical Trial Status

Clinical Trial Status for sacubitril; valsartan
Clinical Trial Phase Trials
Recruiting 35
Completed 21
Not yet recruiting 18
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Clinical Trial Sponsors for sacubitril; valsartan

Sponsor Name

Sponsor Name for sacubitril; valsartan
Sponsor Trials
Novartis Pharmaceuticals 20
Brigham and Women's Hospital 4
The Heartbeat Trust 3
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Sponsor Type

Sponsor Type for sacubitril; valsartan
Sponsor Trials
Other 117
Industry 27
NIH 4
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