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Last Updated: March 29, 2024

CLINICAL TRIALS PROFILE FOR MEGESTROL ACETATE


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All Clinical Trials for megestrol acetate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000737 ↗ A Phase I/II Study to Evaluate Single Agent and Combination Therapy With Megestrol Acetate and Dronabinol for the Treatment of HIV-Wasting Syndrome Completed Bristol-Myers Squibb Phase 1 1969-12-31 To obtain data on the safety of administering megestrol acetate and dronabinol as single agents or in combination to patients with human immunodeficiency virus (HIV)-wasting syndrome. To obtain preliminary data on the efficacy of single agent and combination therapy with megestrol acetate and dronabinol with regard to weight gain, appetite increase and quality of life in this patient population. To obtain steady-state pharmacokinetics data when megestrol acetate and dronabinol are administered as single agents and in combination. HIV-wasting syndrome, which is characterized by severely debilitating anorexia and weight loss, is of particular concern because it can exacerbate the primary illness and is associated with a poor prognosis. Attempts at maintaining body mass through the use of megestrol acetate and dronabinol, two anti-cachectic drugs, may prolong survival.
NCT00000737 ↗ A Phase I/II Study to Evaluate Single Agent and Combination Therapy With Megestrol Acetate and Dronabinol for the Treatment of HIV-Wasting Syndrome Completed Roxane Laboratories Phase 1 1969-12-31 To obtain data on the safety of administering megestrol acetate and dronabinol as single agents or in combination to patients with human immunodeficiency virus (HIV)-wasting syndrome. To obtain preliminary data on the efficacy of single agent and combination therapy with megestrol acetate and dronabinol with regard to weight gain, appetite increase and quality of life in this patient population. To obtain steady-state pharmacokinetics data when megestrol acetate and dronabinol are administered as single agents and in combination. HIV-wasting syndrome, which is characterized by severely debilitating anorexia and weight loss, is of particular concern because it can exacerbate the primary illness and is associated with a poor prognosis. Attempts at maintaining body mass through the use of megestrol acetate and dronabinol, two anti-cachectic drugs, may prolong survival.
NCT00000737 ↗ A Phase I/II Study to Evaluate Single Agent and Combination Therapy With Megestrol Acetate and Dronabinol for the Treatment of HIV-Wasting Syndrome Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 1 1969-12-31 To obtain data on the safety of administering megestrol acetate and dronabinol as single agents or in combination to patients with human immunodeficiency virus (HIV)-wasting syndrome. To obtain preliminary data on the efficacy of single agent and combination therapy with megestrol acetate and dronabinol with regard to weight gain, appetite increase and quality of life in this patient population. To obtain steady-state pharmacokinetics data when megestrol acetate and dronabinol are administered as single agents and in combination. HIV-wasting syndrome, which is characterized by severely debilitating anorexia and weight loss, is of particular concern because it can exacerbate the primary illness and is associated with a poor prognosis. Attempts at maintaining body mass through the use of megestrol acetate and dronabinol, two anti-cachectic drugs, may prolong survival.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for megestrol acetate

Condition Name

Condition Name for megestrol acetate
Intervention Trials
Anorexia 15
Cachexia 13
HIV Infections 9
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Condition MeSH

Condition MeSH for megestrol acetate
Intervention Trials
Cachexia 19
Wasting Syndrome 18
Endometrial Neoplasms 16
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Clinical Trial Locations for megestrol acetate

Trials by Country

Trials by Country for megestrol acetate
Location Trials
United States 221
Canada 15
China 14
South Africa 5
United Kingdom 3
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Trials by US State

Trials by US State for megestrol acetate
Location Trials
California 16
North Carolina 14
Illinois 12
Florida 11
Pennsylvania 11
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Clinical Trial Progress for megestrol acetate

Clinical Trial Phase

Clinical Trial Phase for megestrol acetate
Clinical Trial Phase Trials
Phase 4 6
Phase 3 15
Phase 2/Phase 3 11
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Clinical Trial Status

Clinical Trial Status for megestrol acetate
Clinical Trial Phase Trials
Completed 33
Recruiting 16
Terminated 7
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Clinical Trial Sponsors for megestrol acetate

Sponsor Name

Sponsor Name for megestrol acetate
Sponsor Trials
National Cancer Institute (NCI) 17
Fudan University 7
Xiaojun Chen 4
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Sponsor Type

Sponsor Type for megestrol acetate
Sponsor Trials
Other 82
Industry 25
NIH 21
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