CLINICAL TRIALS PROFILE FOR LOMUSTINE

All Clinical Trials for lomustine

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00002569 ↗	Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma	Completed	Eastern Cooperative Oncology Group	Phase 3	1994-07-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without chemotherapy in treating patients who have anaplastic oligodendroglioma.
NCT00002569 ↗	Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma	Completed	National Cancer Institute (NCI)	Phase 3	1994-07-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without chemotherapy in treating patients who have anaplastic oligodendroglioma.
NCT00002569 ↗	Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma	Completed	NCIC Clinical Trials Group	Phase 3	1994-07-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without chemotherapy in treating patients who have anaplastic oligodendroglioma.
NCT00002569 ↗	Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma	Completed	North Central Cancer Treatment Group	Phase 3	1994-07-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without chemotherapy in treating patients who have anaplastic oligodendroglioma.
NCT00002569 ↗	Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma	Completed	Southwest Oncology Group	Phase 3	1994-07-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without chemotherapy in treating patients who have anaplastic oligodendroglioma.
NCT00002569 ↗	Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma	Completed	Radiation Therapy Oncology Group	Phase 3	1994-07-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without chemotherapy in treating patients who have anaplastic oligodendroglioma.
NCT00002806 ↗	Chemotherapy Followed by Radiation Therapy in Treating Adults With Supratentorial Glioma	Completed	National Cancer Institute (NCI)	Phase 2	1996-07-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining radiation therapy with chemotherapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of procarbazine, lomustine, and vincristine followed by radiation therapy in treating adults who have supratentorial glioma.

Clinical Trial Conditions for lomustine

Condition Name

Condition Name for lomustine
Intervention	Trials
Glioblastoma	26
Brain and Central Nervous System Tumors	18
Glioblastoma Multiforme	15
Recurrent Glioblastoma	8

Condition MeSH

Condition MeSH for lomustine
Intervention	Trials
Glioblastoma	57
Nervous System Neoplasms	24
Central Nervous System Neoplasms	24
Glioma	12

Clinical Trial Locations for lomustine

Trials by Country

Trials by Country for lomustine
Location	Trials
United States	652
Canada	82
Australia	36
United Kingdom	30
Italy	29

Trials by US State

Trials by US State for lomustine
Location	Trials
California	29
New York	29
Ohio	27
Texas	26
Illinois	25

Clinical Trial Progress for lomustine

Clinical Trial Phase

Clinical Trial Phase for lomustine
Clinical Trial Phase	Trials
PHASE3	2
PHASE2	3
PHASE1	1

Clinical Trial Status

Clinical Trial Status for lomustine
Clinical Trial Phase	Trials
Completed	43
Not yet recruiting	18
Recruiting	15

Clinical Trial Sponsors for lomustine

Sponsor Name

Sponsor Name for lomustine
Sponsor	Trials
National Cancer Institute (NCI)	27
European Organisation for Research and Treatment of Cancer - EORTC	10
Children's Oncology Group	7

Sponsor Type

Sponsor Type for lomustine
Sponsor	Trials
Other	132
Industry	49
NIH	28