Hormonal Ablation, Imatinib Mesylate and Docetaxel for Patients With Prostate Cancer
Completed
Novartis Pharmaceuticals
Phase 2
2003-06-01
Primary Objective:
1. To evaluate the pathological complete response rate to neoadjuvant hormonal ablation,
Imatinib and Docetaxel (HID) in high-risk localized prostate cancer.
Secondary Objectives:
1. To describe the time to prostate specific antigen (PSA)-progression after neoadjuvant
HID and radical prostatectomy in high-risk localized prostate cancer.
2. To correlate pathological response with modulation of the Platelet-Derived Growth Factor
Receptor (PDGFR) pathway.
Hormonal Ablation, Imatinib Mesylate and Docetaxel for Patients With Prostate Cancer
Completed
M.D. Anderson Cancer Center
Phase 2
2003-06-01
Primary Objective:
1. To evaluate the pathological complete response rate to neoadjuvant hormonal ablation,
Imatinib and Docetaxel (HID) in high-risk localized prostate cancer.
Secondary Objectives:
1. To describe the time to prostate specific antigen (PSA)-progression after neoadjuvant
HID and radical prostatectomy in high-risk localized prostate cancer.
2. To correlate pathological response with modulation of the Platelet-Derived Growth Factor
Receptor (PDGFR) pathway.
Safety, Efficacy, and Pharmacokinetic Behavior of Leuprolide Mesylate in Subjects With Advanced Prostate Carcinoma
Completed
QPS-Qualitix
Phase 3
2014-08-01
The study will evaluate if Leuprolide Mesylate is safe and effective in the treatment of
subjects with advanced prostate carcinoma, when administered as two injections six months
apart.
Safety, Efficacy, and Pharmacokinetic Behavior of Leuprolide Mesylate in Subjects With Advanced Prostate Carcinoma
Completed
Foresee Pharmaceuticals Co., Ltd.
Phase 3
2014-08-01
The study will evaluate if Leuprolide Mesylate is safe and effective in the treatment of
subjects with advanced prostate carcinoma, when administered as two injections six months
apart.
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