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Fuji
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Boehringer Ingelheim
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Generated: July 17, 2018

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CLINICAL TRIALS PROFILE FOR IOTHALAMATE SODIUM

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Clinical Trials for iothalamate sodium

Trial ID Title Status Sponsor Phase Summary
NCT00270829 Renal Effects of Intrarenal Nesiritide Terminated University of Maryland Phase 4 The impact of nesiritide in CHF is unclear, but it is possible that systemic vasodilation leads to adverse consequences even if the direct renal effects are positive. Therefore, this study will look at the effects of direct intrarenal administration of nesiritide on GFR and RPF.
NCT01836809 Nesiritide and Renal Function After the Total Artificial Heart Terminated Virginia Commonwealth University Phase 4 The prevalence of renal dysfunction after implantation of the artificial heart is high. The infusion of exogenous B-type natriuretic peptide (BNP) after implantation of the total artificial heart (TAH) improves renal function in a sustained manner. The renal protective and hormone-modulating effects of nesiritide may be enhanced with ventriculectomy compared to heart failure surgery that leaves the native myocardium intact. The goal of this project is to determine the renal protective effects of nesiritide after implantation of a mechanical device.
NCT01970176 Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2) Recruiting Mayo Clinic Phase 1/Phase 2 To determine the effect of 12 weeks of chronic PDEV inhibition with Tadalafil versus placebo on basal cardiorenal and humoral function and on the integrated cardiorenal and humoral response to acute sodium loading in subjects with preclinical systolic dysfunction (PSD) and renal (kidney) dysfunction.
NCT02058095 Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3) Recruiting Mayo Clinic Phase 1/Phase 2 To determine the effect of 12 weeks of chronic PDEV inhibition with Tadalafil versus placebo on basal cardiorenal and humoral function and on the integrated cardiorenal and humoral response to acute sodium loading in subjects with preclinical Diastolic dysfunction (PDD) and renal (kidney) dysfunction
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for iothalamate sodium

Condition Name

Condition Name for iothalamate sodium
Intervention Trials
Cardiomyopathy 2
Renal Impairment 2
Renal Disfunction 1
Heart Failure, Congestive 1
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Condition MeSH

Condition MeSH for iothalamate sodium
Intervention Trials
Heart Failure 3
Renal Insufficiency 3
Cardiomyopathies 2
Cardio-Renal Syndrome 2
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Clinical Trial Locations for iothalamate sodium

Trials by Country

Trials by Country for iothalamate sodium
Location Trials
United States 5
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Trials by US State

Trials by US State for iothalamate sodium
Location Trials
Minnesota 3
Virginia 1
Maryland 1
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Clinical Trial Progress for iothalamate sodium

Clinical Trial Phase

Clinical Trial Phase for iothalamate sodium
Clinical Trial Phase Trials
Phase 4 2
Phase 1/Phase 2 2
Phase 1 1
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Clinical Trial Status

Clinical Trial Status for iothalamate sodium
Clinical Trial Phase Trials
Recruiting 2
Terminated 2
Enrolling by invitation 1
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Clinical Trial Sponsors for iothalamate sodium

Sponsor Name

Sponsor Name for iothalamate sodium
Sponsor Trials
Mayo Clinic 3
University of Maryland 1
National Institutes of Health (NIH) 1
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Sponsor Type

Sponsor Type for iothalamate sodium
Sponsor Trials
Other 5
NIH 2
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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Harvard Business School
Express Scripts
McKinsey
Dow
US Army
Fish and Richardson
Cerilliant
McKesson

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