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Generated: August 19, 2018

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CLINICAL TRIALS PROFILE FOR HYDROCHLOROTHIAZIDE; TRIAMTERENE

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Clinical Trials for hydrochlorothiazide; triamterene

Trial ID Title Status Sponsor Phase Summary
NCT00000525 Diuretics, Hypertension, and Arrhythmias Clinical Trial Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 To determine whether hypertensive patients with ECG abnormalities and receiving hydrochlorothiazide diuretics were at increased risk of sudden death.
NCT00000525 Diuretics, Hypertension, and Arrhythmias Clinical Trial Completed University of California, San Francisco Phase 3 To determine whether hypertensive patients with ECG abnormalities and receiving hydrochlorothiazide diuretics were at increased risk of sudden death.
NCT00007592 Hypertension Screening and Treatment Program Completed VA Office of Research and Development N/A Hypertension is one of the most common medical problems in the United States and in the VA health care system. It has been well-documented that hypertension can be effectively treated. However, there remain important unresolved clinical questions in the area of antihypertensive treatment. For example, how much is mortality affected by visit compliance, blood pressure control and type of antihypertensive agent? Or, are some regimens associated with more morbidity than others? Or, are there inexpensive regimens that are as effective as more expensive regimens? The amount of data that is available from this demonstration project (currently 6,100 patients) will help address these questions. The answers to these questions should result in better care for veterans with hypertension.
NCT01661777 Refractory Eustachian Tube Dysfunction: Are the Symptoms Related to Endolymphatic Hydrops Withdrawn Vanderbilt University N/A The purpose of this study is to evaluate the benefit of treatment of refractory Eustachian tube dysfunction with standard treatment for endolymphatic hydrops. Eustachian tube dysfunction is a common diagnosis made in otolaryngology related to abnormal pressure equalization of the middle ear space related to a swollen, inflamed, or occluded Eustachian tube. The symptoms of this include perceived hearing loss, a feeling of fullness in the affected ear/ears, ear pain, ear popping, and occasionally imbalance. These symptoms overlap with a more rare and difficult to diagnose condition known as endolymphatic hydrops, or an overproduction to fluid in the inner ear. The treatment for these two conditions are distinct and traditionally, patients are treated for Eustachian tube dysfunction first as it is much more common and there are several treatments, namely nasal steroids, antihistamines, and pressure equalization tubes. For patients who do not improve with these treatments, they are often treated with diuretics and a low salt diet to treat for supposed endolymphatic hydrops. There has never been a study to investigate the utility of these treatments in patients with refractory Eustachian tube dysfunction. There is also reason to believe that chronic ETD with effusion can lead to both inner and middle ear dysfunction. Thus, this study aims to determine the benefit of standard endolymphatic hydrops treatment on patient with refractory Eustachian tube dysfunction symptoms in a prospective fashion. Hypothesis: Patients with refractory Eustachian tube dysfunction (patients with no or minimal symptom improvement despite nasal steroid and antihistamine treatment followed by myringotomy tube placement) have an element of endolymphatic hydrops and these patient's symptoms will improve with a low sodium diet and diuretic.
NCT02217852 Treatment of Hypertension in Tibetan Adult Population Unknown status West China Hospital Phase 4 Several surveys had revealed that Tibetan adults had high prevalence of hypertension. However, there was no research studying the antihypertensive effect of the known drugs in Tibetan. The main arms of our study were to determine if the efficacy of lowing blood pressure and protecting target organ damage differs between nitrendipine and Hydrochlorothiazide in mild hypertension in Tibetan, and to determine if the efficacy of lowing blood pressure and protecting target organ damage differs between captopril plus Hydrochlorothiazide and Beijing hypotensive No.0 in moderate and severe Tibetan hypertension.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for hydrochlorothiazide; triamterene

Condition Name

Condition Name for hydrochlorothiazide; triamterene
Intervention Trials
Hypertension 3
Cardiovascular Diseases 1
Heart Diseases 1
Heart Arrest 1
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Condition MeSH

Condition MeSH for hydrochlorothiazide; triamterene
Intervention Trials
Hypertension 3
Cardiovascular Diseases 1
Edema 1
Heart Diseases 1
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Clinical Trial Locations for hydrochlorothiazide; triamterene

Trials by Country

Trials by Country for hydrochlorothiazide; triamterene
Location Trials
United States 11
Puerto Rico 1
China 1
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Trials by US State

Trials by US State for hydrochlorothiazide; triamterene
Location Trials
Tennessee 2
District of Columbia 1
California 1
Virginia 1
Pennsylvania 1
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Clinical Trial Progress for hydrochlorothiazide; triamterene

Clinical Trial Phase

Clinical Trial Phase for hydrochlorothiazide; triamterene
Clinical Trial Phase Trials
Phase 4 1
Phase 3 1
N/A 2
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Clinical Trial Status

Clinical Trial Status for hydrochlorothiazide; triamterene
Clinical Trial Phase Trials
Completed 2
Unknown status 1
Withdrawn 1
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Clinical Trial Sponsors for hydrochlorothiazide; triamterene

Sponsor Name

Sponsor Name for hydrochlorothiazide; triamterene
Sponsor Trials
National Heart, Lung, and Blood Institute (NHLBI) 1
West China Hospital 1
Vanderbilt University 1
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Sponsor Type

Sponsor Type for hydrochlorothiazide; triamterene
Sponsor Trials
Other 3
NIH 1
U.S. Fed 1
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Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
Teva
US Army
Daiichi Sankyo
Cipla
Deloitte
Healthtrust
Federal Trade Commission
Fish and Richardson

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