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Last Updated: March 29, 2024

CLINICAL TRIALS PROFILE FOR ERYTHROMYCIN ETHYLSUCCINATE


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All Clinical Trials for erythromycin ethylsuccinate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01323582 ↗ Comparison of Two Macrolides, Azithromycin and Erythromycin, for Symptomatic Treatment of Gastroparesis Terminated Metabolic Solutions Inc. Phase 2 2009-02-01 Erythromycin is effectively used in the treatment of Gastroparesis (GP) patients. In susceptible patients however, it has been associated with sudden cardiac death due to prolongation of QT intervals and subsequent cardiac risks through its interaction some other drugs. Azithromycin (AZI) is a macrolide antibiotic but does not have the mentioned druf interactions , has fewer gastrointestinal side effects, and fewer risks of QT prolongation and cardiac arrhythmias. Consequently, AZI avoids drawbacks of dosing with erythromycin and may be preferred as a prokinetic agent in patients on other concomitant medications. We hope to demonstrate the effectiveness of Azithromycin (AZI) as compared to Erythromycin in the treatment of Gastroparesis (GP), and later, form the framework for larger randomized-controlled parallel studies to investigate use of AZI for treatment of GP. Our novel hypothesis is to determine whether AZI can be used to treat GP.
NCT01323582 ↗ Comparison of Two Macrolides, Azithromycin and Erythromycin, for Symptomatic Treatment of Gastroparesis Terminated University of Florida Phase 2 2009-02-01 Erythromycin is effectively used in the treatment of Gastroparesis (GP) patients. In susceptible patients however, it has been associated with sudden cardiac death due to prolongation of QT intervals and subsequent cardiac risks through its interaction some other drugs. Azithromycin (AZI) is a macrolide antibiotic but does not have the mentioned druf interactions , has fewer gastrointestinal side effects, and fewer risks of QT prolongation and cardiac arrhythmias. Consequently, AZI avoids drawbacks of dosing with erythromycin and may be preferred as a prokinetic agent in patients on other concomitant medications. We hope to demonstrate the effectiveness of Azithromycin (AZI) as compared to Erythromycin in the treatment of Gastroparesis (GP), and later, form the framework for larger randomized-controlled parallel studies to investigate use of AZI for treatment of GP. Our novel hypothesis is to determine whether AZI can be used to treat GP.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for erythromycin ethylsuccinate

Condition Name

Condition Name for erythromycin ethylsuccinate
Intervention Trials
Gastroparesis 1
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Condition MeSH

Condition MeSH for erythromycin ethylsuccinate
Intervention Trials
Gastroparesis 1
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Clinical Trial Locations for erythromycin ethylsuccinate

Trials by Country

Trials by Country for erythromycin ethylsuccinate
Location Trials
United States 1
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Trials by US State

Trials by US State for erythromycin ethylsuccinate
Location Trials
Florida 1
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Clinical Trial Progress for erythromycin ethylsuccinate

Clinical Trial Phase

Clinical Trial Phase for erythromycin ethylsuccinate
Clinical Trial Phase Trials
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for erythromycin ethylsuccinate
Clinical Trial Phase Trials
Terminated 1
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Clinical Trial Sponsors for erythromycin ethylsuccinate

Sponsor Name

Sponsor Name for erythromycin ethylsuccinate
Sponsor Trials
University of Florida 1
Metabolic Solutions Inc. 1
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Sponsor Type

Sponsor Type for erythromycin ethylsuccinate
Sponsor Trials
Other 1
Industry 1
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