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Generated: July 24, 2019

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CLINICAL TRIALS PROFILE FOR DEFERASIROX

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Clinical Trials for deferasirox

Trial ID Title Status Sponsor Phase Summary
NCT00061750 Safety & Efficacy of ICL670 vs. Deferoxamine in Beta-thalassemia Patients With Iron Overload Due to Blood Transfusions Completed Novartis Pharmaceuticals Phase 3 The purpose of this study is to deterimine if the new orally active iron chelator, ICL670, is as effective and as safe as deferoxamine in preventing accumulation of iron in the body while a patient is undergoing repeated blood transfusions.
NCT00061763 Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias Completed Novartis Pharmaceuticals Phase 2 The purpose of this study is to determine the effects of the oral iron chelator Deferasirox on liver iron content after one year of treatment in patients with iron overload from repeated blood transfusions. Beta-thalassemia patients unable to be treated with deferoxamine or patients with rare chronic anemias such as Myelodysplastic Syndrome, Fanconi's Syndrome, Blackfan-Diamond Syndrome, and Pure Red Blood Cell Anemia are eligible for this study. Liver iron content will be measured by liver biopsy at the beginning of the study and after one year of treatment. However, those patients living in the San Francisco/Oakland area may have a SQUID in place of the liver biopsy if the biopsy is not medically possible for them. The SQUID is a non-invasive magnetic means to measure liver iron content.
NCT00067080 Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood Transfusions Completed Novartis Pharmaceuticals Phase 2 The purpose of this study is to determine if the new orally active iron chelator, ICL670, is as safe as deferoxamine in preventing accumulation of iron in the body while a patient is undergoing repeated blood transfusions.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for deferasirox

Condition Name

Condition Name for deferasirox
Intervention Trials
Iron Overload 15
Myelodysplastic Syndromes 12
Beta-Thalassemia 7
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Condition MeSH

Condition MeSH for deferasirox
Intervention Trials
Iron Overload 49
Thalassemia 32
Preleukemia 24
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Clinical Trial Locations for deferasirox

Trials by Country

Trials by Country for deferasirox
Location Trials
United States 204
Italy 60
Canada 21
China 19
United Kingdom 17
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Trials by US State

Trials by US State for deferasirox
Location Trials
California 22
New York 17
Illinois 15
Pennsylvania 14
Texas 12
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Clinical Trial Progress for deferasirox

Clinical Trial Phase

Clinical Trial Phase for deferasirox
Clinical Trial Phase Trials
Phase 4 20
Phase 3 10
Phase 2/Phase 3 2
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Clinical Trial Status

Clinical Trial Status for deferasirox
Clinical Trial Phase Trials
Completed 52
Recruiting 11
Unknown status 6
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Clinical Trial Sponsors for deferasirox

Sponsor Name

Sponsor Name for deferasirox
Sponsor Trials
Novartis Pharmaceuticals 48
Novartis 10
Soroka University Medical Center 2
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Sponsor Type

Sponsor Type for deferasirox
Sponsor Trials
Other 70
Industry 63
NIH 3
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Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
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