The purpose of this study is to determine if the mydriatic effect of intracameral lidocaine
1% is as effective as topical cyclopentolate 1% and phenylephrine 10% for achieving effective
mydriasis during phacoemulsification surgery.
The purpose of this study is to determine whether tropicamide + phenylephrine cyclopentolate
+ applied for once waiting 30 minutes to retinoscopy (new scheme) is not inferior to apply
cyclopentolate alone and wait 45 minutes to retinoscopy (traditional scheme)
Comparison of Epinephrine and Phenylephrine/Ketorolac With Regards to Pupil Size
Terminated
Milton S. Hershey Medical Center
Phase 4
2016-09-01
The objective of this study is to compare the maintenance of intraoperative mydriasis during
cataract surgery between two drugs: epinephrine, which has routinely been used for decades,
and Omidria, a newly FDA approved combination drug of phenylephrine and ketorolac. Patients
undergoing cataract surgery that are enrolled in the trial will randomly receive one of the
drugs in one eye, and the other eye will receive the drug during the subsequent cataract
surgery.
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