Last Updated: June 25, 2026

CLINICAL TRIALS PROFILE FOR APRACLONIDINE HYDROCHLORIDE

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All Clinical Trials for apraclonidine hydrochloride

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00567411 ↗	Comparison of the Alpha-2 Agonists for Prevention of Intraocular Pressure Elevation After Selective Laser Trabeculoplasty	Unknown status	Walter Reed Army Medical Center	N/A	2006-08-01	The purpose of the study is to compare the safety and efficacy of two drops used to lower eye pressure when given prior to a glaucoma laser procedure.
NCT05045248 ↗	Efficacy of Apraclonidine Eye Drops in the Treatment of Ptosis Secondary to Myasthenia Gravis	Completed	American University of Beirut Medical Center	Phase 2	2020-06-01	This study is aimed at assessing the efficacy of Apraclonidine eye drops in the treatment of ptosis secondary to myasthenia gravis.
NCT05167760 ↗	Efficacy of Topical Apraclonidine for the Treatment of Ocular Synkinesis	Not yet recruiting	University of Alabama at Birmingham	Phase 4	2022-02-01	The purpose of this study is to determine efficacy of apraclonidine for patients with ocular synkinesis, who are seen in the UAB Facial Nerve Clinic.
NCT06444529 ↗	A Double-Masked Comparison of FID 123320 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness	COMPLETED	Alcon Research	PHASE3	2024-08-21	The purpose of this study is to assess the safety and efficacy of Apraclonidine Hydrochloride Ophthalmic Solution 0.125% when compared to Vehicle, in relieving redness of the eye due to minor eye irritations. This study will be conducted in the United States.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for apraclonidine hydrochloride

Condition Name

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Condition Name for apraclonidine hydrochloride
Intervention	Trials
Ocular Redness	1
Synkinesis	1
Facial Nerve Palsy	1
Glaucoma	1
[disabled in preview]	1
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Condition MeSH

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Condition MeSH for apraclonidine hydrochloride
Intervention	Trials
Glaucoma	1
Facial Paralysis	1
Facial Nerve Diseases	1
Bell Palsy	1
[disabled in preview]	1
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Clinical Trial Locations for apraclonidine hydrochloride

Trials by Country

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Trials by Country for apraclonidine hydrochloride
Location	Trials
United States	6
Lebanon	1
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Trials by US State

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Trials by US State for apraclonidine hydrochloride
Location	Trials
Alabama	1
District of Columbia	1
Virginia	1
Pennsylvania	1
North Carolina	1
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Clinical Trial Progress for apraclonidine hydrochloride

Clinical Trial Phase

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Clinical Trial Phase for apraclonidine hydrochloride
Clinical Trial Phase	Trials
PHASE3	1
Phase 4	1
Phase 2	1
[disabled in preview]	1
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Clinical Trial Status

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Clinical Trial Status for apraclonidine hydrochloride
Clinical Trial Phase	Trials
COMPLETED	2
Unknown status	1
Not yet recruiting	1
[disabled in preview]	0
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Clinical Trial Sponsors for apraclonidine hydrochloride

Sponsor Name

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Sponsor Name for apraclonidine hydrochloride
Sponsor	Trials
Walter Reed Army Medical Center	1
American University of Beirut Medical Center	1
University of Alabama at Birmingham	1
[disabled in preview]	1
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Sponsor Type

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Sponsor Type for apraclonidine hydrochloride
Sponsor	Trials
Other	2
U.S. Fed	1
INDUSTRY	1
[disabled in preview]	0
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