Venlafaxine With or Without Zolpidem in Treating Hot Flashes and Associated Sleep Disorders in Women With Breast Cancer OR at High Risk for Developing Breast Cancer
Massachusetts General Hospital
RATIONALE: Venlafaxine may be effective in relieving hot flashes caused by hormone therapy.
Giving venlafaxine with zolpidem (a sleeping pill) may improve sleep and quality of life in
women who are receiving hormone therapy for treatment or prevention of breast cancer.
PURPOSE: This randomized clinical trial is studying giving venlafaxine together with zolpidem
to see how well it works compared to venlafaxine alone in relieving hot flashes and
associated sleep disorders in women who are receiving hormone therapy to treat or prevent
Residual Effects of Zolpidem Tartrate Extended Release and Eszopiclone Vs Placebo
Investigation of Psychomotor and Cognitive Residual Effects of Single Oral Doses of Zolpidem
Tartrate Extended Release 12.5 mg and Eszopiclone 3 mg Compared to Placebo in Healthy Young
Volunteers, Using Flurazepam 30 mg as an External Comparator
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