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Generated: September 17, 2019

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CLINICAL TRIALS PROFILE FOR ZOFRAN

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Clinical Trials for Zofran

Trial ID Title Status Sponsor Phase Summary
NCT00000443 Ondansetron Treatment for Alcoholism Completed National Institute on Alcohol Abuse and Alcoholism (NIAAA) Phase 2 The purpose of this study is to: a) evaluate the effectiveness of ondansetron (Zofran) in the treatment of alcohol dependent patients; b) investigate whether early versus late onset alcoholism predicts treatment outcome; and c) determine whether the early and late onset groups respond differently to treatment. Individuals will be "typed" into early onset and late onset alcoholism groups. Individuals will be randomly assigned to a 12-week outpatient treatment program.
NCT00006205 Alcohol Dependency Study: Combining Medication Treatment for Alcoholism Unknown status National Institute on Alcohol Abuse and Alcoholism (NIAAA) Phase 2 The purpose of this study is to learn whether ondansetron and topiramate either alone or in combination is safe and effective in the treatment of alcohol dependence. This 13 week out-patient clinical trial is randomized, double-blind, and placebo-controlled. There are post-study follow up visits 1, 2 and 3 months after the end of the study. Participants will receive ondansetron and topiramate either alone or in combination or a placebo coupled with psychotherapy.
NCT00006205 Alcohol Dependency Study: Combining Medication Treatment for Alcoholism Unknown status Bankole Johnson Phase 2 The purpose of this study is to learn whether ondansetron and topiramate either alone or in combination is safe and effective in the treatment of alcohol dependence. This 13 week out-patient clinical trial is randomized, double-blind, and placebo-controlled. There are post-study follow up visits 1, 2 and 3 months after the end of the study. Participants will receive ondansetron and topiramate either alone or in combination or a placebo coupled with psychotherapy.
NCT00027079 Combined Pharmacotherapies for Alcoholism (Naltrexone/Ondansetron) Completed National Institute on Alcohol Abuse and Alcoholism (NIAAA) Phase 2 This study will compare the effectiveness of ondansetron (Zofran) and naltrexone (ReVia) both alone and in combination in treating Early Onset Alcoholics versus Late Onset Alcoholics. All subjects will received standardized Cognitive Behavioral Therapy. Followup assessments will be completed at 1, 3, 6, and 9 months after treatment.
NCT00050167 Evaluation of Differing Taxanes/Taxane Combinations on the Outcome of Patients With Operable Breast Cancer Completed Roche Pharma AG Phase 1 Primary Objectives: - Determine the impact of each regimen on the disease free and overall survival of patients with operable breast cancer. - Determine the ability of docetaxel/capecitabine to downstage primary breast cancer when administered in the neoadjuvant setting when compared with weekly paclitaxel. - Determine the ability of each regimen to enhance breast conservation therapy when administered in the neoadjuvant setting. (See protocol text for additional objectives and details).
>Trial ID >Title >Status >Phase >Summary

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Clinical Trial Conditions for Zofran

Condition Name

Condition Name for Zofran
Intervention Trials
Healthy 15
Nausea 9
Alcoholism 6
Postoperative Nausea and Vomiting 5
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Condition MeSH

Condition MeSH for Zofran
Intervention Trials
Vomiting 23
Nausea 22
Postoperative Nausea and Vomiting 14
Alcoholism 7
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Clinical Trial Locations for Zofran

Trials by Country

Trials by Country for Zofran
Location Trials
United States 82
Canada 19
Germany 10
India 9
Italy 4
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Trials by US State

Trials by US State for Zofran
Location Trials
Texas 22
New York 7
Virginia 5
Pennsylvania 4
California 4
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Clinical Trial Progress for Zofran

Clinical Trial Phase

Clinical Trial Phase for Zofran
Clinical Trial Phase Trials
Phase 4 18
Phase 3 11
Phase 2/Phase 3 2
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Clinical Trial Status

Clinical Trial Status for Zofran
Clinical Trial Phase Trials
Completed 51
Recruiting 15
Active, not recruiting 8
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Clinical Trial Sponsors for Zofran

Sponsor Name

Sponsor Name for Zofran
Sponsor Trials
M.D. Anderson Cancer Center 10
National Institute on Alcohol Abuse and Alcoholism (NIAAA) 7
Par Pharmaceutical, Inc. 7
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Sponsor Type

Sponsor Type for Zofran
Sponsor Trials
Other 82
Industry 50
NIH 11
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