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Last Updated: January 19, 2022

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CLINICAL TRIALS PROFILE FOR ZIAGEN

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All Clinical Trials for Ziagen

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00004585 ↗ A Study of the Safety and Effectiveness of Combination Anti-HIV Therapy in HIV-Infected Adults Completed Glaxo Wellcome Phase 4 1999-10-01 The purpose of this study is to see if a certain combination of anti-HIV drugs is safe and effective in HIV-infected patients. The drug combination includes a tablet containing lamivudine and zidovudine (called Combivir) plus abacavir plus efavirenz.
NCT00004981 ↗ Safety and Effectiveness of Three Anti-HIV Drugs Combined in One Pill (Trizivir) Unknown status Glaxo Wellcome Phase 3 1969-12-31 The purpose of this study is to look at the safety and effectiveness of a pill called Trizivir that is a combination of three anti-HIV drugs (zidovudine, lamivudine, and abacavir). Zidovudine and lamivudine are often given combined in one pill (Combivir). In this study, Trizivir will be compared to Combivir plus abacavir.
NCT00005017 ↗ Effectiveness and Safety of Epivir/Ziagen/Zerit (3TC/ABC/d4T) Versus Epivir/Ziagen/Sustiva (3TC/ABC/EFV) Versus Epivir/Ziagen/Agenerase/Norvir (3TC/ABC/APV/RTV) in HIV Patients Who Have Never Received Treatment Unknown status Glaxo Wellcome Phase 4 1969-12-31 The purpose of this study is to see how effective and safe it is to give 1 of the 3 following treatments to patients who may not have received anti-HIV treatment: 1) lamivudine (3TC)/abacavir (ABC)/stavudine (d4T); 2) 3TC/ABC/efavirenz (EFV); or 3) 3TC/ABC/amprenavir (APV)/ritonavir (RTV).
NCT00038506 ↗ Study Of Investigational Regimen Combining FDA Approved HIV Drugs In HIV Subjects Experiencing Early Virologic Failure Completed ViiV Healthcare Phase 4 2002-03-01 This study is a 48-week study to evaluate the efficacy and safety of an investigational regimen combining FDA approved HIV drugs in antiretroviral-experienced subjects failing on their first highly active antiretroviral therapy regimen.
NCT00085943 ↗ KALETRA Or LEXIVA With Ritonavir Combined With EPIVIR And Abacavir In Naive Subjects Over 48 Weeks Completed GlaxoSmithKline Phase 3 2004-05-01 This study will compare the ability of fosamprenavir 700 mg with ritonavir 100 mg twice a day or lopinavir 400 mg with ritonavir 100 mg twice a day both combined with a fixed dose combination tablet of abacavir 600 mg and lamivudine 300 mg once a day to suppress virus levels of HIV to less than 400 copies/mL of blood. In addition we will study the safety and tolerability of these compounds over the 48 week study period in patients naive to anti-HIV therapy.
NCT00102960 ↗ Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at Birth Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 3 2005-07-01 The purpose of this study is to compare the effects of anti-HIV drug courses of different lengths in infants who became HIV infected at birth.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Ziagen

Condition Name

Condition Name for Ziagen
Intervention Trials
HIV Infections 7
HIV 3
HIV Infection 2
Cardiovascular Disease 1
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Condition MeSH

Condition MeSH for Ziagen
Intervention Trials
HIV Infections 10
Infections 4
Infection 4
Communicable Diseases 3
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Clinical Trial Locations for Ziagen

Trials by Country

Trials by Country for Ziagen
Location Trials
United States 60
Germany 4
Canada 3
Italy 3
India 2
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Trials by US State

Trials by US State for Ziagen
Location Trials
New York 5
California 5
Florida 4
Texas 4
District of Columbia 3
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Clinical Trial Progress for Ziagen

Clinical Trial Phase

Clinical Trial Phase for Ziagen
Clinical Trial Phase Trials
Phase 4 6
Phase 3 4
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Ziagen
Clinical Trial Phase Trials
Completed 11
Unknown status 2
Recruiting 1
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Clinical Trial Sponsors for Ziagen

Sponsor Name

Sponsor Name for Ziagen
Sponsor Trials
Glaxo Wellcome 3
GlaxoSmithKline 3
ViiV Healthcare 2
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Sponsor Type

Sponsor Type for Ziagen
Sponsor Trials
Other 12
Industry 9
NIH 4
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Serving leading biopharmaceutical companies globally:

Baxter
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Harvard Business School
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AstraZeneca

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