Tofacitinib (Xeljanz) Special Investigation for Rheumatoid Arthritis
Active, not recruiting
The objective of this Surveillance is to verify the following subject matters concerning
Tofacitinib (Xeljanz) under general practice.
1) Occurrence of adverse reactions, factors that may potentially affect safety and efficacy
2） Long-term safety (particularly, malignant tumors and serious infections) and efficacy
Occurrences of malignant tumors and serious infections will be compared with a control
An Open-Label Pilot Study To Evaluate The Efficacy Of Tofacitinib In Moderate To Severe Alopecia Areata, Totalis And Universalis
Active, not recruiting
Locks of Love
This is an open-label pilot study of tofacitinib taken daily for 6 months in the treatment
of moderate to severe AA, and alopecia totalis or universalis, followed by 6 months
follow-up off drug to assess the incidence and timing of recurrence of disease or
documentation of delayed response to treatment. There will be the option of increasing the
treatment duration up to an additional 6 months beyond the initially scheduled 6 months of
treatment, if clinically indicated, and at the discretion of the investigator.
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