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Generated: February 19, 2019

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CLINICAL TRIALS PROFILE FOR XELJANZ

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Clinical Trials for Xeljanz

Trial ID Title Status Sponsor Phase Summary
NCT01932372 Tofacitinib (Xeljanz) Special Investigation for Rheumatoid Arthritis Active, not recruiting Pfizer N/A The objective of this Surveillance is to verify the following subject matters concerning Tofacitinib (Xeljanz) under general practice. 1) Occurrence of adverse reactions, factors that may potentially affect safety and efficacy 2) Long-term safety (particularly, malignant tumors and serious infections) and efficacy Occurrences of malignant tumors and serious infections will be compared with a control group.
NCT02157012 Evaluation of the Condition of Rheumatoid Arthritis After Treatment Recruiting Showa Inan General Hospital Phase 4 To examine the safety and effectiveness after Xeljanz treatment in rheumatoid arthritis patients
NCT02157012 Evaluation of the Condition of Rheumatoid Arthritis After Treatment Recruiting Shinshu University Phase 4 To examine the safety and effectiveness after Xeljanz treatment in rheumatoid arthritis patients
NCT02299297 An Open-Label Pilot Study To Evaluate The Efficacy Of Tofacitinib In Moderate To Severe Alopecia Areata, Totalis And Universalis Active, not recruiting Locks of Love Phase 2 This is an open-label pilot study of tofacitinib taken daily for 6 months in the treatment of moderate to severe AA, and alopecia totalis or universalis, followed by 6 months follow-up off drug to assess the incidence and timing of recurrence of disease or documentation of delayed response to treatment. There will be the option of increasing the treatment duration up to an additional 6 months beyond the initially scheduled 6 months of treatment, if clinically indicated, and at the discretion of the investigator.
NCT02299297 An Open-Label Pilot Study To Evaluate The Efficacy Of Tofacitinib In Moderate To Severe Alopecia Areata, Totalis And Universalis Active, not recruiting Julian M. Mackay-Wiggan Phase 2 This is an open-label pilot study of tofacitinib taken daily for 6 months in the treatment of moderate to severe AA, and alopecia totalis or universalis, followed by 6 months follow-up off drug to assess the incidence and timing of recurrence of disease or documentation of delayed response to treatment. There will be the option of increasing the treatment duration up to an additional 6 months beyond the initially scheduled 6 months of treatment, if clinically indicated, and at the discretion of the investigator.
NCT02996500 Safety and Efficacy of Pf-06650833 In Subjects With Rheumatoid Arthritis, With An Inadequate Response To Methotrexate Recruiting Pfizer Phase 2 This is a Phase 2, multicenter, randomized, double blind, double dummy, placebo and active-controlled, parallel group study to assess the efficacy and safety of PF 06650833 at Week 12 in subjects with moderate-severe, active, RA who have had an inadequate response to MTX. PF-06650833 or matching placebo tablets will be administered orally QD under fasting conditions, and tofacitinib or matching tofacitinib placebo tablets will be administered orally BID for 12 weeks in a blinded fashion.
NCT03000439 A Safety, Efficacy And Pharmacokinetics Study Of Tofacitinib In Pediatric Patients With sJIA Not yet recruiting Pfizer Phase 3 A randomized withdrawal study in which responders to open-label treatment with tofacitinib will be randomized in a 1:1 ratio to tofacitinib or placebo in a double-blind phase. In the double-blind phase "time to sJIA flare" will be evaluated as primary endpoint and subjects will be discontinued once they experience sJIA flare. Once 31 flares are reported the study will be completed.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Xeljanz

Condition Name

Condition Name for Xeljanz
Intervention Trials
Rheumatoid Arthritis 3
Alopecia Areata 2
Arthritis Juvenile Idiopathic 1
Systemic Sclerosis 1
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Condition MeSH

Condition MeSH for Xeljanz
Intervention Trials
Arthritis 4
Arthritis, Rheumatoid 3
Alopecia Areata 2
Alopecia 2
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Clinical Trial Locations for Xeljanz

Trials by Country

Trials by Country for Xeljanz
Location Trials
United States 6
Japan 1
Thailand 1
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Trials by US State

Trials by US State for Xeljanz
Location Trials
Pennsylvania 2
Oregon 1
Texas 1
Florida 1
New York 1
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Clinical Trial Progress for Xeljanz

Clinical Trial Phase

Clinical Trial Phase for Xeljanz
Clinical Trial Phase Trials
Phase 4 2
Phase 3 1
Phase 2 2
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Clinical Trial Status

Clinical Trial Status for Xeljanz
Clinical Trial Phase Trials
Not yet recruiting 4
Active, not recruiting 2
Recruiting 2
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Clinical Trial Sponsors for Xeljanz

Sponsor Name

Sponsor Name for Xeljanz
Sponsor Trials
Pfizer 5
Showa Inan General Hospital 1
Institute of Dermatology, Thailand 1
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Sponsor Type

Sponsor Type for Xeljanz
Sponsor Trials
Other 7
Industry 5
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Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
Boehringer Ingelheim
Fish and Richardson
Queensland Health
US Department of Justice
Fuji
Chubb
Daiichi Sankyo
AstraZeneca

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