Voltaren being a Non-steroidal anti-inflammatory drug (NSAID) drug may be used as a single
drug therapy in otitis externa being both therapeutic and analgesic thus reducing
consumption of oral analgesia.
Effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) on RAdiographic Damage in Ankylosing Spondylitis
Charite University, Berlin, Germany
This is a randomised, controlled, multi-centre clinical trial on AS patients. Experimental
intervention: continuous (daily) treatment with diclofenac cholestyramine 150 mg (Voltaren
Resinate), divided into 75mg Voltaren twice dailyControl intervention: treatment on-demand
(as needed) with diclofenac-cholestyramine 75 to 150 mg (Voltaren Resinate). The treatment
strategy of the control intervention (on-demand) reflects current clinical practice in AS.
Duration of intervention per patient: 2 years Follow-up per patient: safety assessment 3
months after termination of the trial.
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