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Last Updated: May 30, 2023

CLINICAL TRIALS PROFILE FOR VITRASE

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All Clinical Trials for Vitrase

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00198419 ↗	Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase)	Completed	Bausch & Lomb Incorporated	Phase 1	2004-03-01	The objective of this study was to rule out a greater than 10% incidence of hypersensitivity to Vitrase following a single intradermal injection of 3 USP units Vitrase. Less than or equal to 10% hypersensitivity response was considered acceptable.
NCT00198458 ↗	Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase)	Completed	Bausch & Lomb Incorporated	Phase 1	2004-07-01	The objective of this study was to rule out a greater than 10% incidence of hypersensitivity to Vitrase following a single intradermal injection of 3 USP units Vitrase. Less than or equal to a 10% hypersensitivity response was considered acceptable.
NCT00198471 ↗	Assessment of Intravitreous Injections of Vitrase for Inducing Posterior Vitreous Detachment	Completed	Bausch & Lomb Incorporated	Phase 2	2005-07-01	The purpose of this study is to assess the efficacy of intravitreous injections of Vitrase to induce posterior vitreous detachment(PVD) in subjects with moderate to severe non-proliferative diabetic retinopathy.
NCT00198484 ↗	Evaluation of Vitrase as a Spreading Agent	Completed	Bausch & Lomb Incorporated	Phase 3	2004-10-01	The purpose of this study is to determine whether Vitrase (hyaluronidase for injection) is effective as a spreading agent for other injected drugs prior to ocular surgery
NCT00198497 ↗	Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage	Completed	Bausch & Lomb Incorporated	Phase 3	1999-06-01	The purpose of this study is to determine if intravitreal injection of Vitrase (ovine hyaluronidase) clears vitreous hemorrhage
NCT00198510 ↗	Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage	Completed	Bausch & Lomb Incorporated	Phase 3	1998-11-01	The purpose of this study is to determine if intravitreal injection of Vitrase (ovine hyaluronidase) clears vitreous hemorrhage
NCT00198549 ↗	Evaluation of Vitrase as an Adjuvant to Increase Absorption and Dispersion of Other Injected Anesthetics	Completed	Bausch & Lomb Incorporated	Phase 4	2004-09-01	The purpose of this study is to evaluate Vitrase as an adjuvant to increase absorption and dispersion of other injected anesthetics
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for Vitrase

Condition Name

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Condition Name for Vitrase
Intervention	Trials
Diabetic Retinopathy	3
Drug Hypersensitivity	2
Pain	2
Vitreous Hemorrhage	2
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Condition MeSH

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Condition MeSH for Vitrase
Intervention	Trials
Diabetic Retinopathy	3
Vitreous Hemorrhage	2
Drug Hypersensitivity	2
Hemorrhage	2
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Clinical Trial Locations for Vitrase

Trials by Country

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Trials by Country for Vitrase
Location	Trials
United States	46
Canada	5
United Kingdom	5
Brazil	5
Australia	4
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Trials by US State

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Trials by US State for Vitrase
Location	Trials
California	5
New York	3
Texas	3
Connecticut	2
Ohio	2
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Clinical Trial Progress for Vitrase

Clinical Trial Phase

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Clinical Trial Phase for Vitrase
Clinical Trial Phase	Trials
Phase 4	1
Phase 3	3
Phase 2	1
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Clinical Trial Status

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Clinical Trial Status for Vitrase
Clinical Trial Phase	Trials
Completed	7
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Clinical Trial Sponsors for Vitrase

Sponsor Name

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Sponsor Name for Vitrase
Sponsor	Trials
Bausch & Lomb Incorporated	7
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Sponsor Type

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Sponsor Type for Vitrase
Sponsor	Trials
Industry	7
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