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Last Updated: January 22, 2020

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CLINICAL TRIALS PROFILE FOR UPADACITINIB

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All Clinical Trials for Upadacitinib

Trial ID Title Status Sponsor Phase Start Date Summary
NCT03006068 A Study to Evaluate the Long-Term Safety and Efficacy of ABT-494 in Subjects With Ulcerative Colitis (UC) Enrolling by invitation AbbVie Phase 3 2017-01-31 This study is designed to evaluate the long-term safety and efficacy of ABT-494 in participants with ulcerative colitis (UC) who have not responded at the end of the induction period in Study M14-234 (Substudies 1 and 2), who have had loss of response during the maintenance period of Study M14-234 (Substudy 3), or who have successfully completed Study M14-234.
NCT03086343 A Phase 3 Study to Compare ABT-494 to Abatacept in Subjects With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response or Intolerance to Biologic DMARDs Not yet recruiting AbbVie Phase 3 2017-05-15 The comparison of safety and efficacy of ABT-494 versus abatacept in participants with rheumatoid arthritis on a stable background conventional synthetic Disease Modifying Anti-Rheumatic Drug (csDMARD) who have an inadequate response or intolerance to biologic DMARDs.
NCT03104374 A Study Comparing ABT-494 to Placebo in Participants With Active Psoriatic Arthritis Who Have a History of Inadequate Response to at Least One Biologic Disease Modifying Anti-Rheumatic Drug Enrolling by invitation AbbVie Phase 3 2017-04-17 This is a Phase 3 multicenter study that includes two periods. Period 1 is designed to compare the safety, tolerability, and efficacy of ABT-494 Dose A once daily (QD) and Dose B QD versus placebo in participants with moderately to severely active Psoriatic Arthritis (PsA) who have an inadequate response to Biological Disease Modifying Anti-Rheumatic Drug (bDMARDs). Period 2 evaluates the safety, tolerability and efficacy of ABT-494 Dose A QD and Dose B QD in subjects with PsA who have completed Period 1.
NCT03104400 A Study Comparing ABT-494 to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug Enrolling by invitation AbbVie Phase 3 2017-04-28 This is a Phase 3 multicenter study that includes two periods. Period 1 is designed to compare the safety, tolerability, and efficacy of ABT-494 Dose A once daily (QD) and Dose B QD versus placebo and versus adalimumab every other week (eow) in participants with moderately to severely active Psoriatic Arthritis (PsA) and have an inadequate response to non-biologic DMARDs (DMARD-IR). Period 1 is also designed to compare the efficacy of ABT-494 Dose A QD and Dose B QD versus placebo for the prevention of structural progression. Period 2 evaluates the safety, tolerability and efficacy of ABT-494 Dose A QD and Dose B QD in participants with PsA who have completed Period 1.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Upadacitinib

Condition Name

Condition Name for Upadacitinib
Intervention Trials
Atopic Dermatitis 7
Crohn's Disease 3
Psoriatic Arthritis 2
Ulcerative Colitis (UC) 2
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Condition MeSH

Condition MeSH for Upadacitinib
Intervention Trials
Dermatitis 7
Eczema 7
Dermatitis, Atopic 7
Arthritis 6
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Clinical Trial Locations for Upadacitinib

Trials by Country

Trials by Country for Upadacitinib
Location Trials
United States 311
Japan 70
Canada 39
Hungary 28
Italy 27
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Trials by US State

Trials by US State for Upadacitinib
Location Trials
California 16
Florida 15
Texas 15
Ohio 14
Washington 13
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Clinical Trial Progress for Upadacitinib

Clinical Trial Phase

Clinical Trial Phase for Upadacitinib
Clinical Trial Phase Trials
Phase 3 17
Phase 2 4
Phase 1 2
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Clinical Trial Status

Clinical Trial Status for Upadacitinib
Clinical Trial Phase Trials
Not yet recruiting 11
Recruiting 8
Enrolling by invitation 4
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Clinical Trial Sponsors for Upadacitinib

Sponsor Name

Sponsor Name for Upadacitinib
Sponsor Trials
AbbVie 23
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Sponsor Type

Sponsor Type for Upadacitinib
Sponsor Trials
Industry 23
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