Nutritional Therapy of the Deficits of Oxidation Mitochondrial of the Fatty Acids
Completed
Assistance Publique - Hôpitaux de Paris
N/A
2006-06-01
Usual dietary therapies of mitochondrial fatty acid oxidation disorders (FAO) are based on 3
strategies:
- limitation of lipid intake in the diet;
- supplementation of the diet with medium-chain triglycerides (MCT) for patients affected
with disorders of long-chain FAO;
- some specific supplementations (for example, L-carnitine).
These strategies are often ineffective. The aim of the present study is to evaluate new
therapeutic ways based on the underlying energetic defect observed in these disorders. The
long-term goal is to develop efficient therapies of these disorders.
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